Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Pauline Meij"'
Autor:
Judith R Kroep, Sjoerd H van der Burg, Marten Visser, Linda de Bruin, Pauline Meij, Inge Roozen, Els M E Verdegaal, Caroline E van der Minne, Marij J P Welters, Saskia J Santegoets, Nikki M Loof, Sanne Boekestijn, Pita M de Kok, Inge M Westra
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 11 (2023)
Background The presence of T cells and suppressive myeloid cells in epithelial ovarian cancer (EOC) correlate with good and bad clinical outcome, respectively. This suggests that EOC may be sensitive to adoptive cell therapy with autologous tumor-inf
Externí odkaz:
https://doaj.org/article/23ac6018768843a28d87a7fb513a2cca
Autor:
Jan Pieter R. Koopman, Emma L. Houlder, Jacqueline J. Janse, Miriam Casacuberta-Partal, Olivia A.C. Lamers, Jeroen C. Sijtsma, Claudia de Dood, Stan T. Hilt, Arifa Ozir-Fazalalikhan, Vincent P. Kuiper, Geert V.T. Roozen, Laura M. de Bes-Roeleveld, Yvonne C.M. Kruize, Linda J. Wammes, Hermelijn H. Smits, Lisette van Lieshout, Govert J. van Dam, Inge M. van Amerongen-Westra, Pauline Meij, Paul L.A.M. Corstjens, Simon P. Jochems, Angela van Diepen, Maria Yazdanbakhsh, Cornelis H. Hokke, Meta Roestenberg
Publikováno v:
EBioMedicine, Vol 97, Iss , Pp 104832- (2023)
Summary: Background: A controlled human infection model for schistosomiasis (CHI-S) can speed up vaccine development and provides insight into early immune responses following schistosome exposure. Recently, we established CHI-S model using single-se
Externí odkaz:
https://doaj.org/article/47a3e655db044c188dcbfa221310dd96
Autor:
Laura Garcia-Perez, Marja van Eggermond, Lieke van Roon, Sandra A. Vloemans, Martijn Cordes, Axel Schambach, Michael Rothe, Dagmar Berghuis, Chantal Lagresle-Peyrou, Marina Cavazzana, Fang Zhang, Adrian J. Thrasher, Daniela Salvatori, Pauline Meij, Anna Villa, Jacques J.M. Van Dongen, Jaap-Jan Zwaginga, Mirjam van der Burg, H. Bobby Gaspar, Arjan Lankester, Frank J.T. Staal, Karin Pike-Overzet
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss , Pp 666-682 (2020)
Recombinase-activating gene-1 (RAG1)-deficient severe combined immunodeficiency (SCID) patients lack B and T lymphocytes due to the inability to rearrange immunoglobulin and T cell receptor genes. Gene therapy is an alternative for those RAG1-SCID pa
Externí odkaz:
https://doaj.org/article/054d2c31c1974fd68ef81093f23e0c9c
Autor:
Peter van Balen, Inge Jedema, Marleen M. van Loenen, Renate de Boer, H. M. van Egmond, Renate S. Hagedoorn, Conny Hoogstaten, Sabrina A. J. Veld, Lois Hageman, P. A. G. van Liempt, Jaap-Jan Zwaginga, Pauline Meij, H. Veelken, J. H. F. Falkenburg, Mirjam H. M. Heemskerk
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Graft-vs.-leukemia (GVL) reactivity after HLA-matched allogeneic stem cell transplantation (alloSCT) is mainly mediated by donor T cells recognizing minor histocompatibility antigens (MiHA). If MiHA are targeted that are exclusively expressed on hema
Externí odkaz:
https://doaj.org/article/f6e5e712427544debad871b0b6113093
Autor:
Saskia Santegoets, Sjoerd H van der Burg, Noel de Miranda, Els Verdegaal, Monique K van der Kooij, Marten Visser, Caroline van der Minne, Linda de Bruin, Pauline Meij, Anton Terwisscha van Scheltinga, Marij J Welters, Inge Roozen, Gerrit Jan Liefers, Ellen Kapiteijn
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Background Adoptive cell therapy (ACT) with tumor-reactive T cells has shown consistent clinical efficacy. We evaluated the response to ACT in combination with interferon alpha (IFNa) preconditioning in patients with stage IV metastatic melanoma, mos
Externí odkaz:
https://doaj.org/article/8a791317a23f42e9bd1f266c841518cc
Autor:
Laura Garcia-Perez, Anita Ordas, Kirsten Canté-Barrett, Pauline Meij, Karin Pike-Overzet, Arjan Lankester, Frank J. T. Staal
Publikováno v:
Pharmaceutics, Vol 12, Iss 6, p 549 (2020)
Recent clinical trials using patient’s own corrected hematopoietic stem cells (HSCs), such as for primary immunodeficiencies (Adenosine deaminase (ADA) deficiency, X-linked Severe Combined Immunodeficiency (SCID), X-linked chronic granulomatous dis
Externí odkaz:
https://doaj.org/article/f7384b59646643259df56c913fa8ae80
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 3, Iss C (2016)
In the last decade, many clinical trials with gene- and cell-based therapies were performed and increasing interest in the development was established by (national) authorities, academic developers, and commercial companies. However, until now only e
Externí odkaz:
https://doaj.org/article/c4f6147ecbf54c85918a6255368623f1
Autor:
Marleen M. van Loenen, Renate de Boer, Ellis van Liempt, Pauline Meij, Inge Jedema, J.H. Frederik Falkenburg, Mirjam H.M. Heemskerk
Publikováno v:
Haematologica, Vol 99, Iss 4 (2014)
A sequential, two-step procedure in which T-cell-depleted allogeneic stem cell transplantation is followed by treatment with donor lymphocyte infusion at 6 months can significantly reduce the risk and severity of graft-versus-host disease, with postp
Externí odkaz:
https://doaj.org/article/86df220acf5a404a932d8bd65b4e0ba5
Autor:
Pauline Meij, Inge Jedema, Menno A.W.G. van der Hoorn, Rian Bongaerts, Linda Cox, Amon R. Wafelman, Erik W.A. Marijt, Roel Willemze, J.H. Frederik Falkenburg
Publikováno v:
Haematologica, Vol 97, Iss 8 (2012)
Since HA-1-specific T cells have been shown to make a significant contribution to the clinical responses in patients with relapsed leukemia, we investigated the feasibility of adoptive transfer of in vitro induced HA-1-specific CD8 positive T cells t
Externí odkaz:
https://doaj.org/article/27fa3231d06e4c9a886447396188e049
Autor:
Maarten L. Zandvliet, J.H. Frederik Falkenburg, Ellis van Liempt, Louise A. Veltrop-Duits, Arjan C. Lankester, Jayant S. Kalpoe, Michel G.D. Kester, Dirk M. van der Steen, Maarten J. van Tol, Roel Willemze, Henk-Jan Guchelaar, Marco W. Schilham, Pauline Meij
Publikováno v:
Haematologica, Vol 95, Iss 11 (2010)
Background Human adenovirus can cause morbidity and mortality in immunocompromised patients after allogeneic stem cell transplantation. Reconstitution of adenovirus-specific CD4+ T cells has been reported to be associated with sustained protection fr
Externí odkaz:
https://doaj.org/article/6a6d375cdf8c40048c596327347ce026