Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Pauline Maby"'
Autor:
Joseph Willis, Robert A. Anders, Toshihiko Torigoe, Yoshihiko Hirohashi, Carlo Bifulco, Inti Zlobec, Bernhard Mlecnik, Sandra Demaria, Won-Tak Choi, Pavel Dundr, Fabiana Tatangelo, Annabella Di Mauro, Pamela Baldin, Gabriela Bindea, Florence Marliot, Nacilla Haicheur, Tessa Fredriksen, Amos Kirilovsky, Bénédicte Buttard, Angela Vasaturo, Lucie Lafontaine, Pauline Maby, Carine El Sissy, Assia Hijazi, Amine Majdi, Christine Lagorce, Anne Berger, Marc Van den Eynde, Franck Pagès, Alessandro Lugli, Jérôme Galon
Publikováno v:
Cancers, Vol 15, Iss 16, p 4045 (2023)
Background: The Immunoscore (IS) is a quantitative digital pathology assay that evaluates the immune response in cancer patients. This study reports on the reproducibility of pathologists’ visual assessment of CD3+- and CD8+-stained colon tumors, c
Externí odkaz:
https://doaj.org/article/7426d03a66c4425eabc9e6f970f30903
Autor:
Bernhard Mlecnik, Alessandro Lugli, Gabriela Bindea, Florence Marliot, Carlo Bifulco, Jiun-Kae Jack Lee, Inti Zlobec, Tilman T. Rau, Martin D. Berger, Iris D. Nagtegaal, Elisa Vink-Börger, Arndt Hartmann, Carol I. Geppert, Julie Kolwelter, Susanne Merkel, Robert Grützmann, Marc Van den Eynde, Anne Jouret-Mourin, Alex Kartheuser, Daniel Léonard, Christophe Remue, Julia Wang, Prashant Bavi, Michael H. A. Roehrl, Pamela S. Ohashi, Linh T. Nguyen, SeongJun Han, Heather L. MacGregor, Sara Hafezi-Bakhtiari, Bradly G. Wouters, Giuseppe V. Masucci, Emilia K. Andersson, Eva Zavadova, Michal Vocka, Jan Spacek, Lubos Petruzelka, Bohuslav Konopasek, Pavel Dundr, Helena Skalova, Kristyna Nemejcova, Gerardo Botti, Fabiana Tatangelo, Paolo Delrio, Gennaro Ciliberto, Michele Maio, Luigi Laghi, Fabio Grizzi, Tessa Fredriksen, Bénédicte Buttard, Lucie Lafontaine, Pauline Maby, Amine Majdi, Assia Hijazi, Carine El Sissy, Amos Kirilovsky, Anne Berger, Christine Lagorce, Christopher Paustian, Carmen Ballesteros-Merino, Jeroen Dijkstra, Carlijn van de Water, Shannon van Lent-van Vliet, Nikki Knijn, Ana-Maria Mușină, Dragos-Viorel Scripcariu, Boryana Popivanova, Mingli Xu, Tomonobu Fujita, Shoichi Hazama, Nobuaki Suzuki, Hiroaki Nagano, Kiyotaka Okuno, Toshihiko Torigoe, Noriyuki Sato, Tomohisa Furuhata, Ichiro Takemasa, Prabhu Patel, Hemangini H. Vora, Birva Shah, Jayendrakumar B. Patel, Kruti N. Rajvik, Shashank J. Pandya, Shilin N. Shukla, Yili Wang, Guanjun Zhang, Yutaka Kawakami, Francesco M. Marincola, Paolo A. Ascierto, Bernard A. Fox, Franck Pagès, Jérôme Galon
Publikováno v:
Cancers, Vol 15, Iss 2, p 418 (2023)
Background: The prognostic value of Immunoscore was evaluated in Stage II/III colon cancer (CC) patients, but it remains unclear in Stage I/II, and in early-stage subgroups at risk. An international Society for Immunotherapy of Cancer (SITC) study ev
Externí odkaz:
https://doaj.org/article/c23a558bb6574ff7a9c3c43460cfaba0
Autor:
Mohamad Hamieh, Jean-François Chatillon, Estelle Dupel, Florence Bayeux, Emilie Fauquembergue, Pauline Maby, Aurelie Drouet, Anne-Bénédicte Duval-Modeste, Sahil Adriouch, Olivier Boyer, Jean-Baptiste Latouche
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Adoptive immunotherapy based on the transfer of anti-tumor cytotoxic T lymphocytes (CTLs) is a promising strategy to cure cancers. However, rapid expansion of numerous highly functional CTLs with long-lived features remains a challenge. Here, we cons
Externí odkaz:
https://doaj.org/article/5c27cdc79eee4f5cb7d39f0366610641
Autor:
Bernhard Mlecnik, Toshihiko Torigoe, Gabriela Bindea, Boryana Popivanova, Mingli Xu, Tomonobu Fujita, Shoichi Hazama, Nobuaki Suzuki, Hiroaki Nagano, Kiyotaka Okuno, Yoshihiko Hirohashi, Tomohisa Furuhata, Ichiro Takemasa, Prabhudas Patel, Hemangini Vora, Birva Shah, Jayendrakumar B. Patel, Kruti N. Rajvik, Shashank J. Pandya, Shilin N. Shukla, Yili Wang, Guanjun Zhang, Takayuki Yoshino, Hiroya Taniguchi, Carlo Bifulco, Alessandro Lugli, Jiun-Kae Jack Lee, Inti Zlobec, Tilman T. Rau, Martin D. Berger, Iris D. Nagtegaal, Elisa Vink-Börger, Arndt Hartmann, Carol I. Geppert, Julie Kolwelter, Susanne Merkel, Robert Grützmann, Marc Van den Eynde, Anne Jouret-Mourin, Alex Kartheuser, Daniel Léonard, Christophe Remue, Julia Wang, Prashant Bavi, Michael H. A. Roehrl, Pamela S. Ohashi, Linh T. Nguyen, SeongJun Han, Heather L. MacGregor, Sara Hafezi-Bakhtiari, Bradly G. Wouters, Giuseppe V. Masucci, Emilia Andersson, Eva Zavadova, Michal Vocka, Jan Spacek, Lubos Petruzelka, Bohuslav Konopasek, Pavel Dundr, Helena Skalova, Kristyna Nemejcova, Gerardo Botti, Fabiana Tatangelo, Paolo Delrio, Gennaro Ciliberto, Michele Maio, Luigi Laghi, Fabio Grizzi, Florence Marliot, Tessa Fredriksen, Bénédicte Buttard, Lucie Lafontaine, Pauline Maby, Amine Majdi, Assia Hijazi, Carine El Sissy, Amos Kirilovsky, Anne Berger, Christine Lagorce, Christopher Paustian, Carmen Ballesteros-Merino, Jeroen Dijkstra, Carlijn Van de Water, Shannon van Lent-van Vliet, Nikki Knijn, Ana-Maria Mușină, Dragos-Viorel Scripcariu, Francesco M. Marincola, Paolo A. Ascierto, Bernard A. Fox, Franck Pagès, Yutaka Kawakami, Jérôme Galon
Publikováno v:
Cancers, Vol 14, Iss 18, p 4346 (2022)
BACKGROUND: In this study, we evaluated the prognostic value of Immunoscore in patients with stage I–III colon cancer (CC) in the Asian population. These patients were originally included in an international study led by the Society for Immunothera
Externí odkaz:
https://doaj.org/article/70d0d8fd94d34e7c9e02ee65d53aa94e
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Colorectal cancers (CRCs) with microsatellite instability (MSI) are due to a defect in the DNA mismatch repair (MMR) system resulting in an accumulation of frame-shift mutations. They are characterized by a tumor microenvironment richer in cytotoxic
Externí odkaz:
https://doaj.org/article/fd8a65e2d3c74d9b89a31a5ee49202bb
Autor:
David Tougeron, Pauline Maby, Nicolas Elie, Emilie Fauquembergue, Florence Le Pessot, Marie Cornic, Jean-Christophe Sabourin, Pierre Michel, Thierry Frébourg, Jean-Baptiste Latouche
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61001 (2013)
BACKGROUND: Colorectal cancers (CRCs) with microsatellite instability (MSI) are associated with a good prognosis and a high density of tumor-infiltrating lymphocytes (TILs). We have undertaken to determine the link between TIL densities and MSI CRC h
Externí odkaz:
https://doaj.org/article/1deeba460be04e0ab5c98566886e6ab2
Autor:
Philippe Rochigneux, Aaron Lisberg, Alejandro Garcia, Samuel Granjeaud, Anne Madroszyk, Stéphane Fattori, Anthony Gonçalves, Raynier Devillier, Pauline Maby, Nassim Salem, Laurent Gorvel, Brice Chanez, Jaklin Gukasyan, James Carroll, Jonathan Goldman, Anne Sophie Chretien, Daniel Olive, Edward B. Garon
Publikováno v:
Clinical Cancer Research. 28:5136-5148
Purpose: Immune checkpoint inhibitors (ICI) have revolutionized the treatment of non–small cell lung cancer (NSCLC), but predictive biomarkers of their efficacy are imperfect. The primary objective is to evaluate circulating immune predictors of pe
Autor:
Edward B. Garon, Daniel Olive, Anne Sophie Chretien, Jonathan Goldman, James Carroll, Jaklin Gukasyan, Brice Chanez, Laurent Gorvel, Nassim Salem, Pauline Maby, Raynier Devillier, Anthony Gonçalves, Stéphane Fattori, Anne Madroszyk, Samuel Granjeaud, Alejandro Garcia, Aaron Lisberg, Philippe Rochigneux
Purpose:Immune checkpoint inhibitors (ICI) have revolutionized the treatment of non–small cell lung cancer (NSCLC), but predictive biomarkers of their efficacy are imperfect. The primary objective is to evaluate circulating immune predictors of pem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36aaebadb7c68a9188466501438e984c
https://doi.org/10.1158/1078-0432.c.6532772
https://doi.org/10.1158/1078-0432.c.6532772
Autor:
Edward B. Garon, Daniel Olive, Anne Sophie Chretien, Jonathan Goldman, James Carroll, Jaklin Gukasyan, Brice Chanez, Laurent Gorvel, Nassim Salem, Pauline Maby, Raynier Devillier, Anthony Gonçalves, Stéphane Fattori, Anne Madroszyk, Samuel Granjeaud, Alejandro Garcia, Aaron Lisberg, Philippe Rochigneux
Supplementary Figure 1: Graphical Abstract Supplementary Figure 2: Overall Survival in NSCLC patients treated with pembrolizumab in KEYNOTE-001 according to EGFR mutation Supplementary Figure 3: Recursive partitioning identified classical monocytes a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49acead115fdc45f34cdbd9666b276b0
https://doi.org/10.1158/1078-0432.22488620
https://doi.org/10.1158/1078-0432.22488620
Autor:
Jean-Baptiste Latouche, Jérôme Galon, Thierry Frébourg, Pierre Michel, Jean-Christophe Sabourin, Jean-Jacques Tuech, Richard Sesboüé, Florence Le Pessot, Jacques Mauillon, Jacques Benichou, Jérôme Leprince, Aurélie Drouet, Emilie Fauquembergue, Nicolas Elie, Tessa Fredriksen, Helen K. Angell, Gabriela Bindea, Hafid Kora, Bernhard Mlecnik, Mohamad Hamieh, David Tougeron, Pauline Maby
Correlation between frameshift mutations and CD8+ TIL density in the second series.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b0d08af32a0e378ce1fb35c26dbad61
https://doi.org/10.1158/0008-5472.22406582
https://doi.org/10.1158/0008-5472.22406582