Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Pauline M. Jamieson"'
Publikováno v:
Endocrinology. 147:4578-4588
The endogenous corticotropin-releasing factor (CRF) type 2 receptor (CRFR2)-selective ligand urocortin 3 is expressed in discrete subcortical brain regions with fibers distributed mainly to hypothalamic and limbic structures. Close anatomical associa
Autor:
Bhawanjit K. Brar, Chien Li, Wylie Vale, Pauline M. Jamieson, Alon Chen, Mike DiGruccio, Kathy A. Lewis, Marilyn H. Perrin
Publikováno v:
Molecular Endocrinology. 19:441-458
Effects of the corticotropin-releasing factor (CRF) family of peptides are mediated through activation of two receptors, CRF receptor (CRFR) 1 and CRFR2. Based on the homology between known mammalian CRFR genes, we have isolated a cDNA encoding the m
Autor:
Christopher J. Kenyon, Ruth Andrew, Gregory C. Jones, Dawn E. W. Livingstone, Brian R. Walker, Kenneth Smith, Pauline M. Jamieson
Publikováno v:
Endocrinology. 141:560-563
The role of glucocorticoids in obesity is poorly understood. Observations in obese men suggest enhanced inactivation of cortisol by 5alpha-reductase and altered reactivation of cortisone to cortisol by 11betahydroxysteroid dehydrogenase type 1 (11bet
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 68:245-250
11Beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD-1) catalyses the interconversion of active corticosterone and inert 11-dehydrocorticosterone. Short-term glucocorticoid excess upregulates 11beta-HSD-1 in liver and hippocampus leading to suggest
Autor:
Karen E. Chapman, Louise J. S. Williams, Jonathan R. Seckl, Pauline M. Jamieson, Yuri Kotelevtsev, John J. Mullins
Publikováno v:
Biochemical Society Transactions. 25:583-587
Autor:
Orna, Issler, Roderick N, Carter, Evan D, Paul, Paul At, Kelly, Henry J, Olverman, Adi, Neufeld-Cohen, Yael, Kuperman, Christopher A, Lowry, Jonathan R, Seckl, Alon, Chen, Pauline M, Jamieson
Publikováno v:
Biology of Mood & Anxiety Disorders
Background Corticotropin-releasing factor type 2 receptors (CRFR2) are suggested to facilitate successful recovery from stress to maintain mental health. They are abundant in the midbrain raphe nuclei, where they regulate serotonergic neuronal activi
Publikováno v:
Endocrinology. 136:4754-4761
11 beta-Hydroxysteroid dehydrogenase (11 beta HSD) catalyzes the conversion of corticosterone to inert 11-dehydrocorticosterone, thus regulating glucocorticoid access to intracellular receptors. This type 1 isoform (11 beta HSD-1) is a bidirectional
Autor:
Wylie Vale, Pauline M. Jamieson, Andrew Luckey, Lixin Wang, József Czimmer, Nicole R. Basa, Yvette Taché, Mulugeta Million
Publikováno v:
Gastroenterology. 125(3)
Corticotropin-releasing factor (CRF) signaling pathways play a key role in the stress response through the activation of CRF(1) and CRF(2) receptors. We investigated the CRF receptor subtypes involved in gastric postoperative ileus.Adult male mice (C
Autor:
John J. Mullins, Val Lyons, Pauline M. Jamieson, Vidya Rajan, Jonathan R. Seckl, Karen E. Chapman, Christopher R. W. Edwards
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 52(2)
11 beta-Hydroxysteroid dehydrogenase (11 beta-HSD) reversibly converts physiological glucocorticoids (cortisol, corticosterone) to inactive 11-dehydro forms, and thus controls glucocorticoid access to receptors in a variety of tissues. We have cloned