Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Pauline M. Dowd"'
Publikováno v:
British Journal of Dermatology. 120:267-275
SUMMARY A pilot study, a double-blind placebo-controlled randomised study and a long term open trial have indicated that nifedipine is effective in the treatment of perniosis. At a dose of 20 mg to 60 mg daily, nifedipine significantly reduced the ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30f4d7b79b5d81b4f2c01ffd351097aa
https://doi.org/10.1111/j.1365-2133.1989.tb07792.x
https://doi.org/10.1111/j.1365-2133.1989.tb07792.x
Publikováno v:
Europe PubMed Central
The effect of topical application of clobetasol propionate ointment (0.05% w/v) on the vascular changes induced by intradermal injections of histamine, calcitonin gene-related peptide, substance P, endothelin-1 and compound 48/80 was studied. Clobeta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcc0d3e548ea2a56f3466b561f02c931
https://doi.org/10.1159/000211427
https://doi.org/10.1159/000211427
Publikováno v:
Europe PubMed Central
The aim of this study was to investigate in human skin in vivo the role of nitric oxide in maintaining resting vascular tone, in the vasodilatation caused by local warming and by ultraviolet B light exposure, and in the response to exogenous calciton
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bf5c81982e27eda1488eb714855eff1
https://doi.org/10.1111/1523-1747.ep12328204
https://doi.org/10.1111/1523-1747.ep12328204
Autor:
Pauline M. Dowd, Helen A. Bull
Publikováno v:
ImmunoMethods. 2:219-226
Prostaglandins are potent mediators of inflammatory and immune responses in human skin and are important effector molecules in the cellular responses to cytokines, especially interleukin-1. In vitro studies have demonstrated that prostaglandins are s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1525c616ec1150ea8e5d50d14ef49596
https://doi.org/10.1006/immu.1993.1025
https://doi.org/10.1006/immu.1993.1025
Autor:
Frederick L. Pearce, Paul F. Courtney, Christopher B Bunker, Malcolm H.A. Rustin, Helen A. Bull, Pauline M. Dowd
Publikováno v:
Journal of Investigative Dermatology. 100:305-309
Basophils have been implicated as a source of histamine and pro-inflammatory eicosanoids in atopic dermatitis. However, mechanisms regulating basophil mediator release are not understood. An H3 receptor involved in the control of histamine synthesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15bbd75e8a1dd2574462b7e722ca092c
https://doi.org/10.1111/1523-1747.ep12469895
https://doi.org/10.1111/1523-1747.ep12469895
Autor:
P. C. Goldsmith, Pauline M. Dowd
Publikováno v:
Dermatologic Clinics. 11:87-95
The new H1 antihistamines are a major therapeutic advancement in the treatment of allergic disorders such as urticaria and allergic rhinitis. Their efficacy combined with greatly reduced sedating and anticholinergic side effects makes the new class o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10da9a037d5ebda4be636a484b7dd243
https://doi.org/10.1016/s0733-8635(18)30285-7
https://doi.org/10.1016/s0733-8635(18)30285-7
Publikováno v:
British Journal of Pharmacology. 107:276-281
1. The histamine receptor sub-types that are involved in the initiation and maintenance of prostacyclin (PGI2) release from human endothelial cells have been investigated. 2. Endothelial cells cultured from umbilical vein (HUVEC) were incubated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88eda910d2335c62b5b64201d7af0539
https://doi.org/10.1111/j.1476-5381.1992.tb12738.x
https://doi.org/10.1111/j.1476-5381.1992.tb12738.x
Autor:
H.S. Jacobs, Julia A. Newton, Pauline M. Dowd, Christopher B Bunker, Gerard S. Conway, Malcolm W. Greaves
Publikováno v:
Clinical and Experimental Dermatology. 16:420-423
Summary Most women with acne are found to have polycystic ovaries on high resolution pelvic ultrasonography, but most of these women do not manifest the other classical clinical characteristics of the polycystic ovary syndrome. We have compared the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc029b77bba764ad1bd6f10f0f2f6c0e
https://doi.org/10.1111/j.1365-2230.1991.tb01226.x
https://doi.org/10.1111/j.1365-2230.1991.tb01226.x
Publikováno v:
Journal of Investigative Dermatology. 97:787-792
The action of histamine on human dermal microvascular endothelial cells and modulation of its effects by the cytokine interleukin-1 and the vasoactive neuropeptide substance P have been investigated. Histamine (10(-6)-10(-3) M) induces release of pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e80ede49b4ff5725a5df4b2e79e54974
https://doi.org/10.1111/1523-1747.ep12486791
https://doi.org/10.1111/1523-1747.ep12486791
Autor:
Pauline M. Dowd, Helen A. Bull
Publikováno v:
British Journal of Pharmacology. 101:703-709
1. In human cultured umbilical vein endothelial cells, interleukin-1 potentiated histamine-induced release of prostacyclin in a time- and concentration-dependent manner. 2. In cells incubated with interleukin-1 for 24 h, maximal potentiation was obse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4c1cd4f963d49a8821543be0dccbea0
https://doi.org/10.1111/j.1476-5381.1990.tb14144.x
https://doi.org/10.1111/j.1476-5381.1990.tb14144.x