Zobrazeno 1 - 10 of 17 pro vyhledávání: '"Pauline Jackson"'
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Akademický článek
Amoxicillin duration and dose for community-acquired pneumonia in children: the CAP-IT factorial non-inferiority RCT
Autor: Sam Barratt, Julia A Bielicki, David Dunn, Saul N Faust, Adam Finn, Lynda Harper, Pauline Jackson, Mark D Lyttle, Colin VE Powell, Louise Rogers, Damian Roland, Wolfgang Stöhr, Kate Sturgeon, Elia Vitale, Mandy Wan, Diana M Gibb, Mike Sharland
Publikováno v: Health Technology Assessment, Vol 25, Iss 60 (2021)
Background: Data are limited regarding the optimal dose and duration of amoxicillin treatment for community-acquired pneumonia in children. Objectives: To determine the efficacy, safety and impact on antimicrobial resistance of shorter (3-day) and lo
Externí odkaz: https://doaj.org/article/0e90f12c77e941da9612c5c56c0edb52
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2
Amoxicillin duration and dose for community-acquired pneumonia in children: the CAP-IT factorial non-inferiority RCT
Autor: Pauline Jackson, Wolfgang Stöhr, Sam Barratt, Mandy Wan, David Dunn, Diana M. Gibb, Julia Bielicki, Mark D Lyttle, Kate Sturgeon, Colin Ve Powell, Mike Sharland, Louise Rogers, Adam Finn, Elia Vitale, Saul N. Faust, Damian Roland, Lynda Harper
Publikováno v: Health Technology Assessment, Vol 25, Iss 60 (2021)
Background Data are limited regarding the optimal dose and duration of amoxicillin treatment for community-acquired pneumonia in children. Objectives To determine the efficacy, safety and impact on antimicrobial resistance of shorter (3-day) and long
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::119986a6f75bebe48575b9de46aae37c
https://pubmed.ncbi.nlm.nih.gov/34738518
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3
Efficacy, safety and impact on antimicrobial resistance of duration and dose of amoxicillin treatment for young children with Community-Acquired Pneumonia: A protocol for a randomIsed controlled Trial (CAP-IT)
Autor: Julia Bielicki, Kate Sturgeon, Adam Finn, Damian Roland, Mike Sharland, Wolfgang Stöhr, Saul N. Faust, Sam Barratt, Paul Little, Colin Powell, Pauline Jackson, Mandy Wan, Lynda Harper, Alastair D Hay, Mark D Lyttle, David Dunn, Diana M. Gibb, Julie V. Robotham
Publikováno v: BMJ Open
Lyttle, M D, Bielicki, J, Barratt, S, Dunn, D, Finn, A, Harper, L, Jackson, P, Powell, C VE, Roland, D, Stöhr, W, Sturgeon, K, Wan, M, Little, P, Faust, S N, Robotham, J, Hay, A, Gibb, D M, Sharland, M 2019, ' Efficacy, safety and impact on antimicrobial resistance of duration and dose of amoxicillin treatment for young children with Community-Acquired Pneumonia : a protocol for a randomIsed controlled Trial (CAP-IT) ', BMJ Open, vol. 9, no. 5, e029875 . https://doi.org/10.1136/bmjopen-2019-029875
IntroductionCommunity-acquired pneumonia (CAP) is a common indication for antibiotic treatment in young children. Data are limited regarding the ideal dose and duration of amoxicillin, leading to practice variation which may impact on treatment failu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c08fa936c7616c98d50b24d1a4d89e53
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4
G331(P) Engaging site research staff in meta-planning to improve recruitment to a randomised controlled trial (the CAP-IT trial); a PERUKI study
Autor: M Hayman, Pauline Jackson, Kate Sturgeon, R Greenwood-Bibby, Lyttle, Sam Barratt, Damian Roland, MZ Ahmad
Publikováno v: ASSOCIATION OF PAEDIATRIC EMERGENCY MEDICINE.
Introduction Engaging busy clinical staff in research can be challenging, but is vital for successful delivery of large randomised control trials (RCT) and observational studies. We aimed to pool the collective experience of site research nurses rega
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::89159a32cbb3dda3ead92478db7d767f
https://doi.org/10.1136/archdischild-2019-rcpch.322
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5
Continuous Rural-Urban Coding for Cancer Disparity Studies: Is It Appropriate for Statistical Analysis?
Autor: Christopher R. Cogle, Jaclyn Hall, Liang Mao, Jue Yang, Nancy S. Hardt, Guangran Deng, Lusine Yaghjyan, Pauline Jackson
Publikováno v: International Journal of Environmental Research and Public Health
International Journal of Environmental Research and Public Health, Vol 16, Iss 6, p 1076 (2019)
Volume 16
Issue 6
Background: The dichotomization or categorization of rural-urban codes, as nominal variables, is a prevailing paradigm in cancer disparity studies. The paradigm represents continuous rural-urban transition as discrete groups, which results in a loss
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bab4393b542bd8097a0102360fee66e
http://europepmc.org/articles/PMC6466258
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Abstract 1823: Directing T cells using multivalent, bispecific chemically self-assembling nanorings (CSANs) to target brain tumors overexpressing EGFR and B7H3 antigens
Autor: Mahathi Patchava, Ozgun Kilic, Pauline Jackson, Carston R. Wagner, Justine Delgado, David A. Largaespada, Ellie Mews
Publikováno v: Cancer Research. 81:1823-1823
Introduction: CNS solid tumors have few therapeutic options and disease progression is rapid especially in pediatrics. Current standard-of-care strategies with radiation and surgery typically result in severe neuroendocrine and cognitive deficiencies
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9090392a46a35bf251da5b5aaa7b4cd0
https://doi.org/10.1158/1538-7445.am2021-1823
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DNA ligase III and DNA ligase IV carry out genetically distinct forms of end joining in human somatic cells
Autor: Adam J. Harvey, Sehyun Oh, Eric A. Hendrickson, Pauline Jackson, Yongbao Wang, Thanh Nguyen, Jacob Zimbric
Publikováno v: DNA Repair. 21:97-110
Ku-dependent C-NHEJ (classic non-homologous end joining) is the primary DNA EJing (end joining) repair pathway in mammals. Recently, an additional EJing repair pathway (A-NHEJ; alternative-NHEJ) has been described. Currently, the mechanism of A-NHEJ
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f65037c9cff7bec8ff36e1677d863625
https://doi.org/10.1016/j.dnarep.2014.04.015
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9
Anxiety-like behavior of mice produced by conditional central expression of the HIV-1 regulatory protein, Tat
Autor: Jason J. Paris, Jay P. McLaughlin, Pauline Jackson, Michelle L. Ganno, Harminder D. Singh
Publikováno v: Psychopharmacology. 231:2349-2360
Human immunodeficiency virus (HIV) infection is associated with substantial increases in generalized anxiety. The HIV regulatory protein, transactivator of transcription (Tat), has been implicated in the neuropathogenesis related to HIV-1 infection.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d22dce7f3911b7516c3dd84c1a12661f
https://doi.org/10.1007/s00213-013-3385-1
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10
PM-05ARHGAP36 AS A NOVEL DRIVER IN HIGH-RISK HUMAN MEDULLOBLASTOMA
Autor: Pauline Jackson, Paramita Das, Jon D. Larson, David A. Largaespada, Branden S. Moriarity
Medulloblastoma (MB) is the most frequent childhood malignancy of the CNS. Current trials aim to identify effective treatments with reduced side effects, but lack of knowledge regarding drivers prevents development of more precise therapies. MB is di
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::183d3861e35bc2f82b104b3cf23ab5a0
https://europepmc.org/articles/PMC4218488/
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