Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Pauline Isakson"'
Autor:
Lydia Scharf, Hannes Axelsson, Aikaterini Emmanouilidi, Nimitha R. Mathew, Daniel J. Sheward, Susannah Leach, Pauline Isakson, Ilya V. Smirnov, Emelie Marklund, Nicolae Miron, Lars-Magnus Andersson, Magnus Gisslén, Ben Murrell, Anna Lundgren, Mats Bemark, Davide Angeletti
Publikováno v:
JCI Insight, Vol 8, Iss 1 (2023)
Understanding persistence and evolution of B cell clones after COVID-19 infection and vaccination is crucial for predicting responses against emerging viral variants and optimizing vaccines. Here, we collected longitudinal samples from patients with
Externí odkaz:
https://doaj.org/article/3af8f63320a84aac8da92ced88e27ffa
Autor:
Göran Landberg, Emma Jonasson, Anna Gustafsson, Paul Fitzpatrick, Pauline Isakson, Joakim Karlsson, Erik Larsson, Andreas Svanström, Svanheidur Rafnsdottir, Emma Persson, Daniel Andersson, Jennifer Rosendahl, Sarunas Petronis, Parmida Ranji, Pernilla Gregersson, Ylva Magnusson, Joakim Håkansson, Anders Ståhlberg
Publikováno v:
Data in Brief, Vol 31, Iss , Pp 105860- (2020)
Patient-derived scaffolds (PDSs) generated from primary breast cancer tumors can be used to model the tumor microenvironment in vitro. Patient-derived scaffolds are generated by repeated detergent washing, removing all cells. Here, we analyzed the pr
Externí odkaz:
https://doaj.org/article/a296415c8e3d41e384ef36b83bd5436b
Autor:
Aleksander Aas, Pauline Isakson, Christian Bindesbøll, Endalkachew A Alemu, Arne Klungland, Anne Simonsen
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0168182 (2017)
Polymorphic variants of the FTO (fat mass and obesity) gene associate with body mass index in humans, but the underlying molecular mechanisms have not been firmly determined. FTO is linked to energy homeostasis via amino acid sensing and is thought t
Externí odkaz:
https://doaj.org/article/adf7c6a49c04485a888e028535ee3ef4
Autor:
Anna Lundgren, Susannah Leach, Hannes Axelsson, Pauline Isakson, Kristina Nyström, Lydia Scharf, Bengt A Andersson, Nicolae Miron, Emelie Marklund, Lars-Magnus Andersson, Magnus Gisslén, Davide Angeletti, Mats Bemark
Publikováno v:
Clinical and Experimental Immunology.
Antigen-specific class-switched antibodies are detected at the same time or even before IgM in serum of non-vaccinated individuals infected with SARS-CoV-2. These derive from the first wave of plasmablasts formed. Hence, the phenotype and specificity
Autor:
Lydia, Scharf, Hannes, Axelsson, Aikaterini, Emmanouilidi, Nimitha R, Mathew, Daniel J, Sheward, Susannah, Leach, Pauline, Isakson, Ilya V, Smirnov, Emelie, Marklund, Nicolae, Miron, Lars-Magnus, Andersson, Magnus, Gisslén, Ben, Murrell, Anna, Lundgren, Mats, Bemark, Davide, Angeletti
Publikováno v:
JCI insight.
Understanding persistence and evolution of B cell clones after COVID-19 infection and vaccination is crucial for predicting responses against emerging viral variants and optimizing vaccines. Here, we collected longitudinal samples from severe COVID-1
Publikováno v:
Transfusion. 62
Autor:
Erik Larsson, Andreas Svanström, Pernilla Gregersson, Emma Jonasson, Anders Ståhlberg, Joakim Håkansson, Parmida Ranji, Svanheidur Rafnsdottir, Göran Landberg, Jennifer Rosendahl, Sarunas Petronis, Joakim Karlsson, Ylva Magnusson, Emma Persson, Anna Gustafsson, Daniel Andersson, Paul A. Fitzpatrick, Pauline Isakson
Publikováno v:
Data in Brief, Vol 31, Iss, Pp 105860-(2020)
Data in Brief
Data in Brief
Patient-derived scaffolds (PDSs) generated from primary breast cancer tumors can be used to model the tumor microenvironment in vitro. Patient-derived scaffolds are generated by repeated detergent washing, removing all cells. Here, we analyzed the pr
Autor:
Pauline Isakson, Suthakar Ganapathy, Zong-Xian Li, Changyan Chen, Hongmei Zhang, Peipei Wang, Yi-Ren Wang, Jinhe Yang, Xiao-Hong Leng, Tongbo Zhu
Publikováno v:
Journal of cellular physiology. 235(1)
The atypical protein kinase C isoform ι (PKCι) is upregulated, which cooperates with mutated KRAS (mu-KRAS) to promote the development of pancreatic cancers. However, the exact role of PKCι in KRAS-mediated pancreatic tumorigenesis is not fully de
Autor:
Jiao Chen, Changyan Chen, Peipei Wang, Suthakar Ganapathy, Hongmei Zhang, Pauline Isakson, Tongbo Zhu, Da-Peng Wei, Dingding Zhang
Publikováno v:
Oncotarget
Pancreatic ductal adenocarcinoma (PDAC) is a fatal malignant disease with 5-year survival rate of less than 6%. Activating mutations of Kras (mu-Kras) are often detected in most of PDAC patients. Although it has been known that oncogenic Kras is the
Publikováno v:
Scientific Reports
Schläfli, Anna; Isakson, Pauline; Garattini, E; Simonsen, Anne; Tschan, Mario (2017). The autophagy scaffold protein ALFY is critical for the granulocytic differentiation of AML cells. Scientific Reports, 7(1), p. 12980. Nature Publishing Group 10.1038/s41598-017-12734-4
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Schläfli, Anna; Isakson, Pauline; Garattini, E; Simonsen, Anne; Tschan, Mario (2017). The autophagy scaffold protein ALFY is critical for the granulocytic differentiation of AML cells. Scientific Reports, 7(1), p. 12980. Nature Publishing Group 10.1038/s41598-017-12734-4
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Acute myeloid leukemia (AML) is a malignancy of myeloid progenitor cells that are blocked in differentiation. Acute promyelocytic leukemia (APL) is a rare form of AML, which generally presents with a t(15;17) translocation causing expression of the f