Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Pauline I.A. de Bruijn"'
Autor:
Pauline I.A. de Bruijn, Mads V. Sorensen, Markus Bleich, Helle A. Praetorius, Iben Skov Jensen, Jens Leipziger, Casper Larsen
Publikováno v:
Larsen, C K, Jensen, I S, Sørensen, M V, de Bruijn, P I, Bleich, M, Prætorius, H & Leipziger, J 2016, ' Hyperaldosteronism after decreased renal K+ excretion in KCNMB2 knockout mice ', American Journal of Physiology: Renal Physiology, vol. 310, no. 10, pp. F1035-46 . https://doi.org/10.1152/ajprenal.00010.2016
The kidney is the primary organ ensuring K+homeostasis. K+is secreted into the urine in the distal tubule by two mechanisms: by the renal outer medullary K+channel (Kir1.1) and by the Ca2+-activated K+channel (KCa1.1). Here, we report a novel knockou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daa01e9b40680f8c20bb870df87ab9dc
https://pure.au.dk/portal/da/publications/hyperaldosteronism-after-decreased-renal-k-excretion-in-kcnmb2-knockout-mice(18aca309-895d-42df-84b7-608f3f62ad3e).html
https://pure.au.dk/portal/da/publications/hyperaldosteronism-after-decreased-renal-k-excretion-in-kcnmb2-knockout-mice(18aca309-895d-42df-84b7-608f3f62ad3e).html
Autor:
Rita D. Marques, Pauline I.A. de Bruijn, Jens Leipziger, Markus Bleich, Mads V. Sorensen, Helle A. Praetorius
Publikováno v:
Marques, R D, de Bruijn, P I A, Sørensen, M V, Bleich, M, Prætorius, H & Leipziger, J G 2012, ' Basolateral P2X receptors mediate inhibition of NaCl transport in mouse medullary thick ascending limb (mTAL). ', American Journal of Physiology: Renal Physiology, vol. 302, pp. F487-94 .
Aarhus University
Aarhus University
Extracellular nucleotides regulate epithelial transport via luminal and basolateral P2 receptors. Renal epithelia express multiple P2 receptors, which mediate significant inhibition of solute absorption. Recently, we identified several P2 receptors i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::845daeb336318310661b31d02cc4e6ce
https://doi.org/10.1152/ajprenal.00570.2011
https://doi.org/10.1152/ajprenal.00570.2011
Autor:
Steen K. Fagerberg, Mette G. Christensen, Jens Leipziger, Randi G. Bjaelde, Pauline I.A. de Bruijn, Helle Jakobsen, Marianne Skals, Helle A. Praetorius
Publikováno v:
Christensen, M, Fagerberg, S K, de Bruijn, P I A, Bjælde, R G, Jakobsen, H, Leipziger, J G, Skals, M G & Prætorius, H 2015, ' [Ca2+]i oscillations and IL-6 release induced by alpha-hemolysin from Escherichia coli require P2 receptor activation in renal epithelia ', Journal of Biological Chemistry, vol. 290, no. 23, pp. 14776-84 . https://doi.org/10.1074/jbc.M115.639526
Urinary tract infections are commonly caused by α-hemolysin (HlyA)-producing Escherichia coli. In erythrocytes, the cytotoxic effect of HlyA is strongly amplified by P2X receptors, which are activated by extracellular ATP released from the cytosol o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68b1c5a147b4f9904e85e0d43d8b669c
https://pubmed.ncbi.nlm.nih.gov/25911098
https://pubmed.ncbi.nlm.nih.gov/25911098
Autor:
Pauline I.A. de Bruijn, Helle A. Praetorius, Sebastian Frische, Jens Leipziger, Nina Himmerkus, Casper Larsen, Markus Bleich
Publikováno v:
ResearcherID
de Bruijn, P I A, Larsen, C K, Frische, S, Himmerkus, N, Praetorius, H A, Bleich, M & Leipziger, J 2015, ' Furosemide-induced urinary acidification is caused by pronounced H+ secretion in the thick ascending limb ', American Journal of Physiology: Renal Physiology, vol. 309, pp. F146-F153 . https://doi.org/10.1152/ajprenal.00154.2015
de Bruijn, P I A, Larsen, C K, Frische, S, Himmerkus, N, Praetorius, H A, Bleich, M & Leipziger, J 2015, ' Furosemide-induced urinary acidification is caused by pronounced H+ secretion in the thick ascending limb ', American Journal of Physiology: Renal Physiology, vol. 309, pp. F146-F153 . https://doi.org/10.1152/ajprenal.00154.2015
The loop diuretic furosemide inhibits NaCl reabsorption in the thick ascending limb (TAL). In addition, furosemide acidifies the urine, which is traditionally explained by increased Na+ loading to the distal tubule causing an activation of H+ secreti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa410f83e62f4db9057ef275760dc497
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000362554200126&KeyUID=WOS:000362554200126
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000362554200126&KeyUID=WOS:000362554200126