Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Pauline G. Dargis"'
Publikováno v:
European Journal of Pharmacology. 394:171-179
Ca(2+) release-activated Ca(2+) current (I(crac)) has been previously characterized biophysically in Jurkat lymphocytes and other non-excitable cells, but pharmacology remains poorly developed. The present objective was to delineate with whole cell r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ff22e1718797064d268ef0271690721
https://doi.org/10.1016/s0014-2999(00)00144-8
https://doi.org/10.1016/s0014-2999(00)00144-8
Autor:
Edward P. Christian, Jayashree Aiyar, Claudia Ann Wilmington Iannotti, Pauline G. Dargis, Jeffrey S. Smith
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 21(4)
The KCNQ family of K+channels has been implicated in several cardiac and neurological disease pathologies. KCNQ2 (Q2) is a brain-derived gene, which in association with KCNQ3 (Q3) has been shown to provide a molecular basis for the neuronal M current
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f43a19689ca97f75309a91778c26b78
https://pubmed.ncbi.nlm.nih.gov/11160379
https://pubmed.ncbi.nlm.nih.gov/11160379
Autor:
John P. Reeves, Jwa Hwa Cho, Edward P. Christian, Jeffrey P. Gardner, Galina Chernaya, Abraham Aviv, Muthuswamy Balasubramanyam, Pauline G. Dargis
Inhibitors of mitochondrial oxidative metabolism have been proposed to interfere with Ca2+ influx mediated by store-operated channels (SOC), secondary to their effects on ATP production. We assessed SOC activity by 45Ca2+ influx and fluorimetric meas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::589871a358f5709e585ada596eb03031
https://europepmc.org/articles/PMC1218516/
https://europepmc.org/articles/PMC1218516/
Autor:
Pauline G. Dargis, Katherine T. Spence, Edward P. Christian, James A. Togo, Edward John Warawa
Publikováno v:
British journal of pharmacology. 119(4)
1. Standard whole cell patch clamp recording techniques were used to study the pharmacological characteristics and site of econazole-mediated inhibition of calcium release-activated calcium current (Icrac) in the human leukaemic T cell line, Jurkat.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59aad8e53d8879520b462697bccb8656
https://pubmed.ncbi.nlm.nih.gov/8904637
https://pubmed.ncbi.nlm.nih.gov/8904637
Publikováno v:
The Journal of membrane biology. 150(1)
We have obtained evidence that the Ca(2+)-selective current activated by Ca2+ store depletion (Ca2+ release-activated Ca2+ current; Icrac) in Jurkat T lymphocytes is augmented in a time-dependent manner by Ca2+ itself. Whole cell patch clamp experime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d25f0fb62653e1f2d1bfca6d84514df
https://pubmed.ncbi.nlm.nih.gov/8699480
https://pubmed.ncbi.nlm.nih.gov/8699480
Autor:
Ann W. Fieles, Michel Goedert, Tyrrell Norris, Virginia M.-Y. Lee, Claudia B. Caputo, Clay W Scott, Mathew M.S. Lo, Pauline G. Dargis
Publikováno v:
Brain research. Molecular brain research. 20(3)
Tau protein is a neuronal microtubule-associated protein that promotes the assembly and stability of microtubules. To evaluate the biological significance of tau isoform diversity, NIH-3T3 cells were stably transfected with cDNAs encoding each of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d56ae9ff3e7091bb576281212289ba
https://pubmed.ncbi.nlm.nih.gov/8302159
https://pubmed.ncbi.nlm.nih.gov/8302159