Zobrazeno 1 - 10 of 18 pro vyhledávání: '"Pauline Chenuet"'
1
Akademický článek
STING-dependent sensing of self-DNA drives silica-induced lung inflammation
Autor: Sulayman Benmerzoug, Stéphanie Rose, Badreddine Bounab, David Gosset, Laure Duneau, Pauline Chenuet, Lucile Mollet, Marc Le Bert, Christopher Lambers, Silvana Geleff, Michael Roth, Louis Fauconnier, Delphine Sedda, Clarisse Carvalho, Olivier Perche, David Laurenceau, Bernhard Ryffel, Lionel Apetoh, Ahmet Kiziltunc, Hakan Uslu, Fadime Sultan Albez, Metin Akgun, Dieudonnée Togbe, Valerie F. J. Quesniaux
Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-19 (2018)
Silica particles induce intereukin-1 (IL-1) response to contribute to lung inflammation, but the underlying mechanism is unclear. Here the authors show that silica induces cell death and release of mitochondria and genomic DNA, which are sensed by ST
Externí odkaz: https://doaj.org/article/9888d37e2d5a425d97df7c19aed7823f
Zobrazit plný text záznamu
2
Akademický článek
Bromodomain and extraterminal (BET) protein inhibition of IgG/IgE production in murine B cells is counter‐balanced by a strong Th2 bias
Autor: Zeinab Dalloul, Marie Best, Pauline Chenuet, Iman Dalloul, Sandrine Le Noir, Dieudonnée Togbé, Mylène Gador, Bernhard Ryffel, Valerie FJ Quesniaux, Yolla El Makhour, François Boyer, Jean‐Claude Aldigier, Jeanne Cook‐Moreau, Nicolas Fazilleau, Michel Cogné
Publikováno v: Clinical & Translational Immunology, Vol 10, Iss 6, Pp n/a-n/a (2021)
Abstract Objectives Inhibitors of bromodomain and extra terminal domain (BET) proteins are a new and growing class of anti‐cancer drugs, which decrease oncogene expression by targeting superenhancers. Antibody production is another physiological pr
Externí odkaz: https://doaj.org/article/7f4552b0dd5f47e48599bdbc8b3cbc6d
Zobrazit plný text záznamu
3
Akademický článek
Potential Role of the Micro-Immunotherapy Medicine 2LALERG in the Treatment of Pollen-Induced Allergic Inflammation
Autor: Ilaria Floris, Pauline Chenuet, Dieudonnée Togbe, Christelle Volteau, Beatrice Lejeune
Publikováno v: Dose-Response, Vol 18 (2020)
In this study, we evaluated the efficacy of a micro-immunotherapy medicine (MIM), 2LALERG, in a preclinical model of allergic respiratory disease sensitized with birch pollen extract (BPE). BALB/c mice were immunized with BPE, or saline solution, and
Externí odkaz: https://doaj.org/article/1fe77fc750f84065a3f572ae03926519
Zobrazit plný text záznamu
4
NLRP6 negatively regulates type 2 immune responses in mice
Autor: Pauline Chenuet, Quentin Marquant, Louis Fauconnier, Ali Youness, Manon Mellier, Tiffany Marchiol, Nathalie Rouxel, Yasmine Messaoud‐Nacer, Isabelle Maillet, Aurélie Ledru, Valérie F. J. Quesniaux, Bernhard Ryffel, William Horsnell, Frédérique Végran, Lionel Apetoh, Dieudonnée Togbe
Publikováno v: Allergy
Allergy, In press, ⟨10.1111/all.15388⟩
International audience; Background: Inflammasomes are large protein complexes that assemble in the cytosol in response to danger such as tissue damage or infection. Following activation, inflammasomes trigger cell death and the release of biologicall
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fb703f67e34f0835c994046c9ba2f3a
https://pubmed.ncbi.nlm.nih.gov/35615773
Zobrazit plný text záznamu
5
The commensal skin microbiota triggers type I IFN–dependent innate repair responses in injured skin
Autor: Sabine Werner, Bernhard Ryffel, Cyrine Belkhodja, Pauline Chenuet, Michel Gilliet, Bernhard Homey, Anissa Fries, Jeremy Di Domizio, Daniel E. Speiser, Curdin Conrad, Paula Marcos Mondéjar, Timothy Murray, Olivier Demaria
Publikováno v: Nature Immunology. 21:1034-1045
Skin wounds heal by coordinated induction of inflammation and tissue repair, but the initiating events are poorly defined. Here we uncover a fundamental role of commensal skin microbiota in this process and show that it is mediated by the recruitment
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b7a8eecc88342baef3e866205aea33
https://doi.org/10.1038/s41590-020-0721-6
Zobrazit plný text záznamu
6
Bromodomain and extraterminal (BET) protein inhibition of IgG/IgE production in murine B cells is counter-balanced by a strong Th2 bias
Autor: Bernhard Ryffel, Yolla Makhour, Zeinab Dalloul, Pauline Chenuet, Jean-Claude Aldigier, Michel Cogné, François Boyer, Marie Best, Valérie F. J. Quesniaux, Sandrine Le Noir, Dieudonnée Togbe, Jeanne Cook-Moreau, Mylène Gador, Nicolas Fazilleau, Iman Dalloul
Publikováno v: Clinical and Translational Immunology
Clinical and Translational Immunology, 2021, 10 (6), pp.e1280. ⟨10.1002/cti2.1280⟩
Clinical and Translational Immunology, Nature Publishing Group, 2021, 10 (6), pp.e1280. ⟨10.1002/cti2.1280⟩
Clinical & Translational Immunology
Clinical & Translational Immunology, Vol 10, Iss 6, Pp n/a-n/a (2021)
Objectives Inhibitors of bromodomain and extra terminal domain (BET) proteins are a new and growing class of anti‐cancer drugs, which decrease oncogene expression by targeting superenhancers. Antibody production is another physiological process rel
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fee329423492909008c682edd2c8e2e
https://doi.org/10.1002/cti2.1280
Zobrazit plný text záznamu
7
Potential Role of the Micro-Immunotherapy Medicine 2LALERG in the Treatment of Pollen-Induced Allergic Inflammation
Autor: Beatrice Lejeune, Pauline Chenuet, Dieudonnée Togbe, Ilaria Floris, Christelle Volteau
Publikováno v: Dose-Response
Dose-Response, Vol 18 (2020)
In this study, we evaluated the efficacy of a micro-immunotherapy medicine (MIM), 2LALERG, in a preclinical model of allergic respiratory disease sensitized with birch pollen extract (BPE). BALB/c mice were immunized with BPE, or saline solution, and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fefec264880f3b505fe8c1206010cfb
http://europepmc.org/articles/PMC7093691
Zobrazit plný text záznamu
8
IL-1R1-MyD88 axis elicits papain-induced lung inflammation
Autor: Matthias Müller, Franco Di Padova, Chloé Michaudel, Isabelle Maillet, Malgorzata Kisielow, Aurélie Couturier-Maillard, Edward D. Crandall, Per Flodby, Bernhard Ryffel, Solenne Vigne, Jessica Le Bérichel, Cem Gabay, Zea Borok, Noëlline Guillou, Pauline Chenuet, Valérie Quesniaux, Jennifer Palomo, Rafiou Agoro, Julie Piotet-Morin, Marc Le Bert
Publikováno v: European Journal of Immunology. 46:2531-2541
Allergic asthma is characterized by a strong Th2 response with inflammatory cell recruitment and structural changes in the lung. Papain is a protease allergen disrupting the airway epithelium triggering a rapid inflammation with eosinophilia mediated
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8ef4891a1818288c69d04b54e246b53b
https://doi.org/10.1002/eji.201646366
Zobrazit plný text záznamu
9
Interleukin-22-deficiency and microbiota contribute to the exacerbation of Toxoplasma gondii-induced intestinal inflammation
Autor: L. Brault, N Froux, Chloé Michaudel, Pauline Chenuet, Valérie F. J. Quesniaux, Bernard Ryffel, Samuel Huber, P Robinet, Laure Dumoutier, J Piotet-Morin, Harry Sokol, Aurélie Couturier-Maillard, J Le Bérichel, S Jejou, A Sénéchal, Mathias Chamaillard, Jean-Christophe Renauld, Juan L. Iovanna
Publikováno v: Mucosal Immunology
Mucosal Immunology, 2018, 11 (4), pp.1181-1190. ⟨10.1038/s41385-018-0005-8⟩
Mucosal Immunology, Nature Pub. Group, 2018, 11 (4), pp.1181-1190. ⟨10.1038/s41385-018-0005-8⟩
Mucosal Immunology, Vol. 11, no. 4, p. 1181-1190 (2018)
International audience; Upon oral infection with Toxoplasma gondii cysts (76 K strain) tachyzoites are released into the intestinal lumen and cross the epithelial barrier causing damage and acute intestinal inflammation in C57BL/6 (B6) mice. Here we
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64cf1c9b036f5d392a305666ccc0ac55
https://hal.sorbonne-universite.fr/hal-04007029
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje