Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Pauline C. A. Chapman"'
Autor:
J. Sydney Davies, Michael Anthony Harris, David J. Merrikin, Richard Keith Anderson, Roger J. Ponsford, Trevor J. Grinter, Carol F. Smith, Christina A. Mitchell, Suzanne C. Cosham, Andrew V. Stachulski, Pauline C. A. Chapman
Publikováno v:
The Journal of Antibiotics. 46:331-342
Syntheses are described for penicillins (4b approximately 4i, 5a and 5b) which possess a 6 beta-(2-heteroaryl-3-substituted)-propenamido side-chain of fixed geometry. In vitro results for these compounds against a range of Gram-positive and Gram-nega
Autor:
J. D. Hinks, Richard L. Elliot, Michael J. Pearson, Suzanne C. Cosham, A. John Eglington, John Lowther, John V. Syms, Pauline C. A. Chapman, Roger J. Ponsford, Michael Anthony Harris, David J. Merrikin, Pamela Brown, Stephen H. Calvert
Publikováno v:
J. Chem. Soc., Perkin Trans. 1. :881-891
A series of (Z)-2-alkyloxyimino-2-(2-aminothiazol-4-yl)acetamidopenicillins has been prepared. New methodology has been developed to prepare tertiary alkyl oximes. High stability to β-lactamases and potent antibacterial activity have been achieved a