Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Pauline C Ng"'
Autor:
Pauline C. Ng, Axel M. Hillmer, Patrick Tan, Thomas D. Barber, Geoffrey B. Nilsen, Jason M. Laramie, Dennis G. Ballinger, Stephen E. Lincoln, Brock A. Peters, Daniel S.W. Tan, Christoph Reinhard, Shenli Zhang, Kun Yu, Joanna H.J. Tan, Yuhao Lin, Gary S.L. Loh, Xiwen Ma, Hui-Hoon Chua, Yong G. Yue, Audrey S.M. Teo, Swee-Seong Wong, Elaine Lim, Jason C. Ting, Philip J. Ebert, Vidhya G. Krishnan
Percentage of somatic variants based on 6 mutation types in Asian lung cancers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45dce352d0eaf466ce951ada5f494ef6
https://doi.org/10.1158/0008-5472.22401582.v1
https://doi.org/10.1158/0008-5472.22401582.v1
Autor:
Pauline C. Ng, Axel M. Hillmer, Patrick Tan, Thomas D. Barber, Geoffrey B. Nilsen, Jason M. Laramie, Dennis G. Ballinger, Stephen E. Lincoln, Brock A. Peters, Daniel S.W. Tan, Christoph Reinhard, Shenli Zhang, Kun Yu, Joanna H.J. Tan, Yuhao Lin, Gary S.L. Loh, Xiwen Ma, Hui-Hoon Chua, Yong G. Yue, Audrey S.M. Teo, Swee-Seong Wong, Elaine Lim, Jason C. Ting, Philip J. Ebert, Vidhya G. Krishnan
Clinical and tissue information on 30 lung cancer patients (S1); Recurrent somatic variants based on presence of the same variant in the COSMIC database or presence of the same variant within the dataset (S2); Variants of the category 'three or more
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51477059a67d33d12c240560c586f66c
https://doi.org/10.1158/0008-5472.22401579.v1
https://doi.org/10.1158/0008-5472.22401579.v1
Autor:
Pauline C. Ng, Axel M. Hillmer, Patrick Tan, Thomas D. Barber, Geoffrey B. Nilsen, Jason M. Laramie, Dennis G. Ballinger, Stephen E. Lincoln, Brock A. Peters, Daniel S.W. Tan, Christoph Reinhard, Shenli Zhang, Kun Yu, Joanna H.J. Tan, Yuhao Lin, Gary S.L. Loh, Xiwen Ma, Hui-Hoon Chua, Yong G. Yue, Audrey S.M. Teo, Swee-Seong Wong, Elaine Lim, Jason C. Ting, Philip J. Ebert, Vidhya G. Krishnan
Asian nonsmoking populations have a higher incidence of lung cancer compared with their European counterparts. There is a long-standing hypothesis that the increase of lung cancer in Asian never-smokers is due to environmental factors such as second-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5be768aae2c157cef8b067bfc6eec390
https://doi.org/10.1158/0008-5472.c.6505890
https://doi.org/10.1158/0008-5472.c.6505890
Autor:
Pauline C. Ng, Axel M. Hillmer, Patrick Tan, Thomas D. Barber, Geoffrey B. Nilsen, Jason M. Laramie, Dennis G. Ballinger, Stephen E. Lincoln, Brock A. Peters, Daniel S.W. Tan, Christoph Reinhard, Shenli Zhang, Kun Yu, Joanna H.J. Tan, Yuhao Lin, Gary S.L. Loh, Xiwen Ma, Hui-Hoon Chua, Yong G. Yue, Audrey S.M. Teo, Swee-Seong Wong, Elaine Lim, Jason C. Ting, Philip J. Ebert, Vidhya G. Krishnan
Legend for Supplementary Figures S1-S2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a845a616e2bc05351e5429df3d688fd
https://doi.org/10.1158/0008-5472.22401588.v1
https://doi.org/10.1158/0008-5472.22401588.v1
Autor:
Michael A Eberle, Pauline C Ng, Kenneth Kuhn, Lixin Zhou, Daniel A Peiffer, Luana Galver, Karine A Viaud-Martinez, Cynthia Taylor Lawley, Kevin L Gunderson, Richard Shen, Sarah S Murray
Publikováno v:
PLoS Genetics, Vol 3, Iss 10, Pp 1827-1837 (2007)
Advances in high-throughput genotyping and the International HapMap Project have enabled association studies at the whole-genome level. We have constructed whole-genome genotyping panels of over 550,000 (HumanHap550) and 650,000 (HumanHap650Y) SNP lo
Externí odkaz:
https://doaj.org/article/6f35ed976e6e4f0ebdc90c7bbf139a85
Autor:
Akash Kumar, Kate Im, Milena Banjevic, Pauline C. Ng, Tate Tunstall, Geronimo Garcia, Luisa Galhardo, Jiayi Sun, Oren N. Schaedel, Brynn Levy, Donna Hongo, Dusan Kijacic, Michelle Kiehl, Nam D. Tran, Peter C. Klatsky, Matthew Rabinowitz
Publikováno v:
Nature medicine. 28(3)
Preimplantation genetic testing (PGT) of in-vitro-fertilized embryos has been proposed as a method to reduce transmission of common disease; however, more comprehensive embryo genetic assessment, combining the effects of common variants and rare vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa457bc41c166e9c4f5576f19fe88f2b
https://pubmed.ncbi.nlm.nih.gov/35314828
https://pubmed.ncbi.nlm.nih.gov/35314828
Autor:
Jing Hu, Pauline C Ng
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77940 (2013)
Indels in the coding regions of a gene can either cause frameshifts or amino acid insertions/deletions. Frameshifting indels are indels that have a length that is not divisible by 3 and subsequently cause frameshifts. Indels that have a length divisi
Externí odkaz:
https://doaj.org/article/b7db0d1e85b348ca9bde61993627a24d
Autor:
Chin Thing J Ong, Qiangze Hoi, Alexis Jiaying Khng, Naoto Takahashi, Zhu En Chan, Audrey S.M. Teo, Axel M. Hillmer, David A. Fruman, Charles Chuah, Wei Jia W Soon, Patrick Tan, Wee Joo Chng, Simeen Malik, King Pan Ng, Kian Leong Lee, Ravi Bhatia, Pauline C. Ng, Tun Kiat Ko, Cheryl Xueli Chan, Xiu Ting Heng, Kim Jiajing Xie, Joanna H.J. Tan, Thushangi N. Pathiraja, Wee Yang Meah, Sheila Xinxuan Soh, Chiea Chuen Khor, Yee Yen Sia, S. Tiong Ong, Oscar Velazquez Camacho, Asif Javed, Xingliang Liu
Publikováno v:
Blood. 135(26)
Targeted therapies against the BCR-ABL1 kinase have revolutionized treatment of chronic phase (CP) chronic myeloid leukemia (CML). In contrast, management of blast crisis (BC) CML remains challenging because BC cells acquire complex molecular alterat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d59614c263f519893a3cec6b928580e4
https://pubmed.ncbi.nlm.nih.gov/32585023
https://pubmed.ncbi.nlm.nih.gov/32585023
Autor:
Pauline C Ng, Samuel Levy, Jiaqi Huang, Timothy B Stockwell, Brian P Walenz, Kelvin Li, Nelson Axelrod, Dana A Busam, Robert L Strausberg, J Craig Venter
Publikováno v:
PLoS Genetics, Vol 4, Iss 8, p e1000160 (2008)
There is much interest in characterizing the variation in a human individual, because this may elucidate what contributes significantly to a person's phenotype, thereby enabling personalized genomics. We focus here on the variants in a person's 'exom
Externí odkaz:
https://doaj.org/article/ec25641b3e3242fd9b4c301b74382959
Autor:
Samuel Levy, Granger Sutton, Pauline C Ng, Lars Feuk, Aaron L Halpern, Brian P Walenz, Nelson Axelrod, Jiaqi Huang, Ewen F Kirkness, Gennady Denisov, Yuan Lin, Jeffrey R MacDonald, Andy Wing Chun Pang, Mary Shago, Timothy B Stockwell, Alexia Tsiamouri, Vineet Bafna, Vikas Bansal, Saul A Kravitz, Dana A Busam, Karen Y Beeson, Tina C McIntosh, Karin A Remington, Josep F Abril, John Gill, Jon Borman, Yu-Hui Rogers, Marvin E Frazier, Stephen W Scherer, Robert L Strausberg, J Craig Venter
Publikováno v:
PLoS Biology, Vol 5, Iss 10, p e254 (2007)
Presented here is a genome sequence of an individual human. It was produced from approximately 32 million random DNA fragments, sequenced by Sanger dideoxy technology and assembled into 4,528 scaffolds, comprising 2,810 million bases (Mb) of contiguo
Externí odkaz:
https://doaj.org/article/1ebc1b9d3b354a3c848c72f1b19274b6