Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Pauline Basso"'
Autor:
Zhongle Liu, Pauline Basso, Saif Hossain, Sean D. Liston, Nicole Robbins, Luke Whitesell, Suzanne M. Noble, Leah E. Cowen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Metabolic flexibility enables fungi to invade challenging host environments. In Candida albicans, a common cause of life-threatening infections in humans, an important contributor to flexibility is alternative oxidase (Aox) activity. Dramati
Externí odkaz:
https://doaj.org/article/77916211e1fb435cbbda60aadd78443d
Autor:
Pierre Wallet, Sacha Benaoudia, Amandine Mosnier, Brice Lagrange, Amandine Martin, Helena Lindgren, Igor Golovliov, Fanny Michal, Pauline Basso, Sophia Djebali, Angelina Provost, Omran Allatif, Etienne Meunier, Petr Broz, Masahiro Yamamoto, Bénédicte F Py, Eric Faudry, Anders Sjöstedt, Thomas Henry
Publikováno v:
PLoS Pathogens, Vol 13, Iss 10, p e1006630 (2017)
Guanylate binding proteins (GBPs) are interferon-inducible proteins involved in the cell-intrinsic immunity against numerous intracellular pathogens. The molecular mechanisms underlying the potent antibacterial activity of GBPs are still unclear. GBP
Externí odkaz:
https://doaj.org/article/0e6ee933e0344ccba71791b83022fc20
Autor:
Pauline Basso, Michel Ragno, Sylvie Elsen, Emeline Reboud, Guillaume Golovkine, Stephanie Bouillot, Philippe Huber, Stephen Lory, Eric Faudry, Ina Attrée
Publikováno v:
mBio, Vol 8, Iss 1 (2017)
ABSTRACT Clinical strains of Pseudomonas aeruginosa lacking the type III secretion system genes employ a toxin, exolysin (ExlA), for host cell membrane disruption. Here, we demonstrated that ExlA export requires a predicted outer membrane protein, Ex
Externí odkaz:
https://doaj.org/article/f6d0809c3fa644599ba0f26864033712
Publikováno v:
Toxins, Vol 9, Iss 11, p 364 (2017)
Bacterial toxins are important weapons of toxicogenic pathogens. Depending on their origin, structure and targets, they show diverse mechanisms of action and effects on eukaryotic cells. Exolysin is a secreted 170 kDa pore-forming toxin employed by c
Externí odkaz:
https://doaj.org/article/ae7f46948c0440ceba70ac35ad07b999
Autor:
Pauline Basso, Eric V. Dang, Anatoly Urisman, Leah E. Cowen, Hiten D. Madhani, Suzanne M. Noble
Publikováno v:
Cell hostmicrobe. 30(11)
Candida albicans is the most common cause of fungal infection in humans. IL-17 is critical for defense against superficial fungal infections, but the role of this response in invasive disease is less understood. We show that C. albicans secretes a li
Publikováno v:
Cell host & microbe, vol 29, iss 6
Cell Host Microbe
Cell Host Microbe
Candida albicans is a fungal component of the human gut microbiota and an opportunistic pathogen. C.albicans transcription factors (TFs), Wor1 and Efg1, are master regulators of an epigenetic switch required for fungal mating that also control coloni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52ecea831acc39189151d07709e6a79d
https://escholarship.org/uc/item/07s278np
https://escholarship.org/uc/item/07s278np
Autor:
Pauline Basso, Thomas Henry, Emmanuelle Soleilhac, Sylvie Elsen, Ina Attree, Pierre Wallet, Eric Faudry
Publikováno v:
Environmental Microbiology. 19:4045-4064
Pathogenic bacteria secrete protein toxins that provoke apoptosis or necrosis of eukaryotic cells. Here, we developed a live-imaging method, based on incorporation of a DNA-intercalating dye into membrane-damaged host cells, to study the kinetics of
Publikováno v:
Environmental Microbiology Reports. 8:564-571
Highly divergent strains of the major human opportunistic pathogen Pseudomonas aeruginosa have been isolated around the world by different research laboratories. They came from patients with various types of infectious diseases or from the environmen
Autor:
Pauline Basso, Sylvie Elsen, Stéphanie Bouillot, Katy Jeannot, Ina Attree, Emeline Reboud, Philippe Huber, Guillaume Golovkine
Publikováno v:
Environmental Microbiology. 18:3425-3439
We recently identified a hypervirulent strain of Pseudomonas aeruginosa, differing significantly from the classical strains in that it lacks the type 3 secretion system (T3SS), a major determinant of P. aeruginosa virulence. This new strain secretes
Autor:
Pauline Basso, Ina Attree, Gwendoline Bellement, Sylvie Elsen, Yohann Couté, Annie Adrait, Stephen Lory, Alice Berry, Erwin Sentausa
Publikováno v:
Microbial Genomics
Microbial Genomics, In press, ⟨10.1099/mgen.0.000265⟩
Microbial Genomics, Society for General Microbiology, In press, ⟨10.1099/mgen.0.000265⟩
Microbial Genomics, In press, ⟨10.1099/mgen.0.000265⟩
Microbial Genomics, Society for General Microbiology, In press, ⟨10.1099/mgen.0.000265⟩
Pseudomonas aeruginosa is a highly adaptive opportunistic pathogen that can have serious health consequences in patients with lung disorders. Taxonomic outliers of P. aeruginosa of environmental origin have recently emerged as infectious for humans.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a46cac0566341d12ace0aa9df045e86