Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Paulina Wyrembek"'
Autor:
Paulina Wyrembek, Jerzy W. Mozrzymas, Marcin Szczot, Katarzyna Szczuraszek, Katarzyna Mercik, Federica Pollastro, Giovanni Appendino, Katarzyna Lebida
Publikováno v:
British Journal of Pharmacology. 160:1302-1315
Background and purpose: Oenanthotoxin (OETX), a polyacetylenic alcohol from plants of the genus Oenanthe, has recently been identified as potent inhibitor of GABA-evoked currents. However, the effects of OETX on the inhibitory postsynaptic currents (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6469fa164deee66f4eacd3bcf3424993
https://doi.org/10.1111/j.1476-5381.2010.00644.x
https://doi.org/10.1111/j.1476-5381.2010.00644.x
Publikováno v:
British Journal of Pharmacology. 154:234-245
Background and purpose: Benzodiazepines (BDZs) are widely used in clinical practice and are known as positive modulators of GABAergic currents. BDZs increase binding affinity and recently they were found to affect GABAA receptor gating, including des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::697d883fc987dd1937fe4137254c6d34
https://doi.org/10.1038/bjp.2008.90
https://doi.org/10.1038/bjp.2008.90
Autor:
Paulina Wyrembek, Katarzyna Lebida, Katarzyna Mercik, Tomasz Wójtowicz, Michał Piast, Jerzy W. Mozrzymas
Publikováno v:
The Journal of Physiology. 585:29-46
Benzodiazepines (BDZs) are known to increase the amplitude and duration of IPSCs. Moreover, at low [GABA], BDZs strongly enhance GABAergic currents suggesting the up-regulation of agonist binding while their action on gating remains a matter of debat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::460198bdfb4869ff105289c9bb788bdb
https://doi.org/10.1113/jphysiol.2007.143602
https://doi.org/10.1113/jphysiol.2007.143602
Publikováno v:
European journal of pharmacology. 683(1-3)
Oenanthotoxin (OETX) and dihydro-OETX are polyacetylenic diols occurring in Oenanthe crocata and are known to exert proconvulsant effects. We have recently demonstrated that these compounds downregulated GABAergic currents (Appendino et al., 2009) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28dc7f8b51f972093e23952efd5ee288
https://pubmed.ncbi.nlm.nih.gov/22445880
https://pubmed.ncbi.nlm.nih.gov/22445880
Autor:
Paulina Wyrembek, Marcin Wawrzyniak, Nikolay I. Medvedev, Leszek Kaczmarek, Grzegorz M. Wilczynski, Dominique Muller, Marcin Szczot, Jerzy W. Mozrzymas, Ewa Wilczek, Katarzyna Mercik, Mathias De Roo, Michael G. Stewart, Jakub Wlodarczyk, Przemyslaw Alot, Werner Zuschratter, Piotr Michaluk
Publikováno v:
Journal of Cell Science, Vol. 124, No Pt 19 (2011) pp. 3369-80
Journal of cell science
Journal of Cell Science; Vol 124
Journal of cell science
Journal of Cell Science; Vol 124
An increasing body of data has shown that matrix metalloproteinase-9 (MMP-9), an extracellularly acting, Zn2+-dependent endopeptidase, is important not only for pathologies of the central nervous system but also for neuronal plasticity. Here, we use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b15b6df20bdee0d90b3278c35c334769
https://archive-ouverte.unige.ch/unige:25597
https://archive-ouverte.unige.ch/unige:25597
Autor:
Paulina, Wyrembek, Katarzyna, Lebida, Katarzyna, Mercik, Katarzyna, Szczuraszek, Marcin, Szczot, Federica, Pollastro, Giovanni, Appendino, Jerzy W, Mozrzymas
Publikováno v:
British journal of pharmacology. 160(6)
Oenanthotoxin (OETX), a polyacetylenic alcohol from plants of the genus Oenanthe, has recently been identified as potent inhibitor of GABA-evoked currents. However, the effects of OETX on the inhibitory postsynaptic currents (IPSCs), as well as the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8dc7c05b9a397c226401d79c4da2d301
https://pubmed.ncbi.nlm.nih.gov/20590622
https://pubmed.ncbi.nlm.nih.gov/20590622
Autor:
Leszek Kaczmarek, Piotr Michaluk, Katarzyna Szczuraszek, Paulina Wyrembek, Jerzy W. Mozrzymas, Tomasz Gorkiewicz
Publikováno v:
Hippocampus. 20(10)
Matrix Metalloproteinase 9 (MMP-9) has been demonstrated to play a crucial role in maintenance of NMDA receptor-dependent LTP and in lateral mobility of these receptors. However, the effect of MMP-9 on NMDA receptor (NMDAR) functional properties is u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f9048610d202fee604a607173f6c3d9
https://pubmed.ncbi.nlm.nih.gov/20043284
https://pubmed.ncbi.nlm.nih.gov/20043284
Autor:
Luisella Verotta, Orazio Taglialatela-Scafati, Paulina Wyrembek, Federica Pollastro, Jerzy W. Mozrzymas, Adriana Romano, Katarzyna Szczuraszek, Giovanni Appendino, Mauro Ballero
Publikováno v:
Journal of Natural Products
An investigation of Oenanthe fistulosa from Sardinia afforded oenanthotoxin (1a) and dihydrooenanthotoxin (1b) from the roots and the diacetylenic epoxydiol 2 from the seeds. The absolute configuration of 1a and 1b was established as R by the modifie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71a2035bb7bbde2d09f71b5c2c959072
http://hdl.handle.net/11588/351741
http://hdl.handle.net/11588/351741
Autor:
Jerzy W, Mozrzymas, Tomasz, Wójtowicz, Michal, Piast, Katarzyna, Lebida, Paulina, Wyrembek, Katarzyna, Mercik
Publikováno v:
The Journal of Physiology
Benzodiazepines (BDZs) are known to increase the amplitude and duration of IPSCs. Moreover, at low [GABA], BDZs strongly enhance GABAergic currents suggesting the up-regulation of agonist binding while their action on gating remains a matter of debat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4b10181b32dad4e147628ea178876309
https://pubmed.ncbi.nlm.nih.gov/17855751
https://pubmed.ncbi.nlm.nih.gov/17855751