Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Paulina Wigner"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-19 (2023)
Abstract Bladder cancer (BC) is a severe health problem of the genitourinary system and is characterised by a high risk of recurrence. According to the recent GLOBOCAN report, bladder cancer accounts for 3% of diagnosed cancers in the world, taking 1
Externí odkaz:
https://doaj.org/article/01f76ea090494b73a55f6662015f7ad3
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 22, p 16094 (2023)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), discovered in December 2019 in Wuhan, China, caused the coronavirus disease 2019 (COVID-19). Due to the rate of spread of this virus, the World Health Organization, in March 2020, recognis
Externí odkaz:
https://doaj.org/article/f0a58ce327bc48309d426a3278e8146d
Autor:
Paulina Wigner, Angela Dziedzic, Ewelina Synowiec, Elzbieta Miller, Michal Bijak, Joanna Saluk-Bijak
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Multiple sclerosis (MS) is a neurodegenerative disease characterized by a variable clinical course and diverse pathophysiology, including nitrative and oxidative stresses as well as inflammation. We aimed to detect the potential association
Externí odkaz:
https://doaj.org/article/6c13ee0b76e7438686c0ca58e744bca4
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0293280 (2023)
Urolithiasis is one of the most common urological diseases worldwide with an unclear aetiology. However, a growing body of evidence suggests the potential role of molecular disturbances of the inflammation as well as oxidative and nitrative stresses,
Externí odkaz:
https://doaj.org/article/5dce5f43526b4863810e2257d36767fe
Autor:
Piotr Czarny, Sylwia Ziółkowska, Łukasz Kołodziej, Cezary Watała, Paulina Wigner-Jeziorska, Katarzyna Bliźniewska-Kowalska, Katarzyna Wachowska, Małgorzata Gałecka, Ewelina Synowiec, Piotr Gałecki, Michał Bijak, Janusz Szemraj, Tomasz Śliwiński
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14752 (2023)
One of the key features of major depressive disorder (MDD, depression) is increased oxidative stress manifested by elevated levels of mtROS, a hallmark of mitochondrial dysfunction, which can arise from mitochondrial DNA (mtDNA) damage. Thus, the cur
Externí odkaz:
https://doaj.org/article/3bc4b835c964414897b960bbafadf0ba
Autor:
Paulina Wigner, Beata Szymańska, Michał Bijak, Ewa Sawicka, Paweł Kowal, Zofia Marchewka, Joanna Saluk-Bijak
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The epidemiological studies confirm that the overproduction of free radical is an important factor of cancer induction as well as development, and loss of antioxidant systems efficiency is associated with an increased risk of carcinogenesis.
Externí odkaz:
https://doaj.org/article/4d4faa01bc8040c2b669954e3753ce7c
Autor:
Paulina Wigner, Krzysztof Zielinski, Sylwia Michlewska, Paulina Danielska, Agnieszka Marczak, Eduardo Junior Ricci, Ralph Santos-Oliveira, Marzena Szwed
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Even though application of nanoparticles in medicine seems to provide unique solutions for drug delivery and diagnosis diseases, understanding interactions between nanoscale materials and biological systems is imperative. Therefore, this stu
Externí odkaz:
https://doaj.org/article/8509673478214422873f51168337be40
Autor:
Paulina Wigner, Krzysztof Zielinski, Magdalena Labieniec-Watala, Agnieszka Marczak, Marzena Szwed
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Doxorubicin (DOX) is considered one of the most powerful chemotherapeutic agents but its clinical use has several limitations, including cardiomyopathy and cellular resistance to the drug. By using transferrin (Tf) as a drug carrier, however
Externí odkaz:
https://doaj.org/article/b33adf26b2264bd79ed3bafd26548ba8
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6266 (2023)
Bladder cancer (BC) is the 10th most common form of cancer globally, but its complete aetiology is still unknown. Nevertheless, there is evidence that chronic inflammation plays a role in the development and progression of BC. Therefore, the presente
Externí odkaz:
https://doaj.org/article/74e3bf98a62f47e29479ddb4ff151089
Autor:
Katarzyna Bialek, Piotr Czarny, Paulina Wigner, Ewelina Synowiec, Lukasz Kolodziej, Michal Bijak, Janusz Szemraj, Mariusz Papp, Tomasz Sliwinski
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 16, p 8983 (2022)
The preclinical research conducted so far suggest that depression development may be influenced by the inflammatory pathways both at the periphery and within the central nervous system. Furthermore, inflammation is considered to be strongly connected
Externí odkaz:
https://doaj.org/article/ba894ecc180647aa9be57e07a411d468