Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Paulina Sosicka"'
Autor:
Paulina Sosicka, Bożena Bazan, Dorota Maszczak-Seneczko, Yauhen Shauchuk, Teresa Olczak, Mariusz Olczak
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 2, p 276 (2019)
Solute carrier family 35 member A5 (SLC35A5) is a member of the SLC35A protein subfamily comprising nucleotide sugar transporters. However, the function of SLC35A5 is yet to be experimentally determined. In this study, we inactivated the SLC35A5 gene
Externí odkaz:
https://doaj.org/article/13fecb41e56449e9bddba94448b0d960
Autor:
Cosimo Commisso, Hudson H. Freeze, Giovanni Brandi, Matthew R. Moldenhauer, Yijuan Zhang, M. Victoria Recouvreux, Michael Jung, Paulina Sosicka, Koen M.O. Galenkamp
abstractCancer cells reprogram their metabolism to meet elevated energy demands and favor glycolysis for energy production. This boost in glycolytic flux supports proliferation, but also generates acid in the form of hydrogen ions that must be elimin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5b29658321de6de5f0d4403a93e276f
https://doi.org/10.1158/2159-8290.c.6547861.v1
https://doi.org/10.1158/2159-8290.c.6547861.v1
Autor:
Cosimo Commisso, Hudson H. Freeze, Giovanni Brandi, Matthew R. Moldenhauer, Yijuan Zhang, M. Victoria Recouvreux, Michael Jung, Paulina Sosicka, Koen M.O. Galenkamp
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37e7b348a37c831f5126dce9d4cae73e
https://doi.org/10.1158/2159-8290.22535446
https://doi.org/10.1158/2159-8290.22535446
Autor:
Cosimo Commisso, Hudson H. Freeze, Giovanni Brandi, Matthew R. Moldenhauer, Yijuan Zhang, M. Victoria Recouvreux, Michael Jung, Paulina Sosicka, Koen M.O. Galenkamp
Supplementary Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5152d2a78692d846ed1e99079b2adc9
https://doi.org/10.1158/2159-8290.22535449
https://doi.org/10.1158/2159-8290.22535449
Publikováno v:
ACS Chem Biol
Congenital disorders of glycosylation (CDG) are ultrarare, genetically and clinically heterogeneous metabolic disorders. Although the number of identified CDG is growing rapidly, there are few therapeutic options. Most treatments involve dietary supp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5590ed3eb9c133a39772f36983e905ea
https://doi.org/10.1021/acschembio.1c00601
https://doi.org/10.1021/acschembio.1c00601
Autor:
Paulina Sosicka, Bobby G. Ng, Lauren E. Pepi, Asif Shajahan, Maurice Wong, David A. Scott, Kenjiroo Matsumoto, Zhi-Jie Xia, Carlito B. Lebrilla, Robert S. Haltiwanger, Parastoo Azadi, Hudson H. Freeze
Publikováno v:
The Journal of cell biology, vol 221, iss 10
Biosynthesis of macromolecules requires precursors such as sugars or amino acids, originating from exogenous/dietary sources, reutilization/salvage of degraded molecules, or de novo synthesis. Since these sources are assumed to contribute to one homo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0490dc79e224c0e8a4eb6f3b84be4588
https://escholarship.org/uc/item/2b07k16w
https://escholarship.org/uc/item/2b07k16w
Autor:
Sonal, Mahajan, Bobby George, Ng, Lama, AlAbdi, Paul Daniel James, Earnest, Paulina, Sosicka, Nisha, Patel, Rana, Helaby, Firdous, Abdulwahab, Miao, He, Fowzan S, Alkuraya, Hudson H, Freeze
Publikováno v:
Journal of medical genetics.
Enzymes of the Golgi implicated in N-glycan processing are critical for brain development, and defects in many are defined as congenital disorders of glycosylation (CDG). Involvement of the Golgi mannosidase, MAN2A2 has not been identified previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::18ad7c48f4717f136b50aab1e78567dc
https://pubmed.ncbi.nlm.nih.gov/36357165
https://pubmed.ncbi.nlm.nih.gov/36357165
Autor:
Paulina Sosicka, Hudson H. Freeze, Dorota Maszczak-Seneczko, Mariusz Olczak, Teresa Olczak, Auhen Shauchuk, Edyta Skurska, Bożena Szulc
Publikováno v:
Journal of Biological Chemistry. 295:16445-16463
Nucleotide sugar transporters, encoded by the SLC35 gene family, deliver nucleotide sugars throughout the cell for various glycosyltransferase-catalyzed glycosylation reactions. GlcNAc, in the form of UDP-GlcNAc, and galactose, as UDP-Gal, are delive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2e9dbb700d124fa0b7b563f5149b29a
https://doi.org/10.1074/jbc.ra119.012362
https://doi.org/10.1074/jbc.ra119.012362
Publikováno v:
Journal of Biological Chemistry. 299:102738
Understanding L-fucose metabolism is important because it is used as a therapy for several congenital disorders of glycosylation. Exogenous L-fucose can be activated and incorporated directly into multiple N- and O-glycans via the fucose salvage/recy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b9885c5fcc61cd654cda72c07c0c636
https://doi.org/10.1016/j.jbc.2022.102738
https://doi.org/10.1016/j.jbc.2022.102738
Autor:
Paulina Sosicka, Robert S. Haltiwanger, Zhi-Jie Xia, Maurice Wong, Asif Shajahan, Lauren E. Pepi, Kenjiroo Matsumoto, Carlito B. Lebrilla, Hudson H. Freeze, Bobby G. Ng, David Scott, Parastoo Azadi
Biosynthesis of macromolecules requires precursors such as sugars or amino acids, originating from exogenous/dietary sources, reutilization/salvage of degraded molecules or de novo synthesis. Since these sources are assumed to contribute to one homog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::301655b3c459ea2c67440bcb37d065f6
https://doi.org/10.1101/2021.11.03.467160
https://doi.org/10.1101/2021.11.03.467160