Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Paulina Prorok"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
The accuracy of replication is one of the most important mechanisms ensuring the stability of the genome. The fork protection complex prevents premature replisome stalling and/or premature disassembly upon stress. Here, we characterize the Timeless
Externí odkaz:
https://doaj.org/article/ef3ac43d26ae4b4599a0f692579abb1c
Autor:
Maruthi Kumar Pabba, Christian Ritter, Vadim O Chagin, Janis Meyer, Kerem Celikay, Jeffrey H Stear, Dinah Loerke, Ksenia Kolobynina, Paulina Prorok, Alice Kristin Schmid, Heinrich Leonhardt, Karl Rohr, M Cristina Cardoso
Publikováno v:
eLife, Vol 12 (2023)
Chromatin has been shown to undergo diffusional motion, which is affected during gene transcription by RNA polymerase activity. However, the relationship between chromatin mobility and other genomic processes remains unclear. Hence, we set out to lab
Externí odkaz:
https://doaj.org/article/53734f9cda4c4f3985e5bcc7dc340b2e
Autor:
Sunil Kumar Pradhan, Teresa Lozoya, Paulina Prorok, Yue Yuan, Anne Lehmkuhl, Peng Zhang, M. Cristina Cardoso
Publikováno v:
Genes, Vol 15, Iss 3, p 305 (2024)
DNA replication is a fundamental process ensuring the maintenance of the genome each time cells divide. This is particularly relevant early in development when cells divide profusely, later giving rise to entire organs. Here, we analyze and compare t
Externí odkaz:
https://doaj.org/article/32fe4fcaffb145dd9a02e1c6f20088dd
Publikováno v:
BMC Veterinary Research, Vol 18, Iss 1, Pp 1-6 (2022)
Abstract Background Urinary tract infestation by Capillaria spp. in domestic cats is rather rare, but can cause clinical symptoms and affect behaviour. To our knowledge, this report is the first to describe a case of urinary capillariosis in a cat in
Externí odkaz:
https://doaj.org/article/f569b034d6aa40e8887f6441d168e018
Autor:
Paulina Prorok, Faezeh Forouzanfar, Nerea Murugarren, Isabelle Peiffer, Romain Charton, Ildem Akerman, Marcel Méchali
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112280- (2023)
Summary: In metazoan cells, DNA replication initiates from thousands of genomic loci scattered throughout the genome called DNA replication origins. Origins are strongly associated with euchromatin, particularly open genomic regions such as promoters
Externí odkaz:
https://doaj.org/article/976b6f795bf04791be7c1e3f2f770e4c
Autor:
Paulina Prorok, Marie Artufel, Antoine Aze, Philippe Coulombe, Isabelle Peiffer, Laurent Lacroix, Aurore Guédin, Jean-Louis Mergny, Julia Damaschke, Aloys Schepers, Christelle Cayrou, Marie-Paule Teulade-Fichou, Benoit Ballester, Marcel Méchali
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Origins of replications are associated with potential G quadruplexes forming structures (G4s). Here the authors reveal the functional role of G4 elements in DNA replication initiation.
Externí odkaz:
https://doaj.org/article/804438238fb24198ab7f18f9282d13ba
Autor:
Paulina Prorok, Inga R. Grin, Bakhyt T. Matkarimov, Alexander A. Ishchenko, Jacques Laval, Dmitry O. Zharkov, Murat Saparbaev
Publikováno v:
Cells, Vol 10, Iss 7, p 1591 (2021)
It was proposed that the last universal common ancestor (LUCA) evolved under high temperatures in an oxygen-free environment, similar to those found in deep-sea vents and on volcanic slopes. Therefore, spontaneous DNA decay, such as base loss and cyt
Externí odkaz:
https://doaj.org/article/43bea6ab572d47bdbdabbccb8ba0d5c6
Autor:
Paulina Prorok, Marie Artufel, Antoine Aze, Philippe Coulombe, Isabelle Peiffer, Laurent Lacroix, Aurore Guédin, Jean-Louis Mergny, Julia Damaschke, Aloys Schepers, Christelle Cayrou, Marie-Paule Teulade-Fichou, Benoit Ballester, Marcel Méchali
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/2599dd8011ea466f8e4033db473e30f0
Autor:
Botagoz Joldybayeva, Paulina Prorok, Inga R Grin, Dmitry O Zharkov, Alexander A Ishenko, Barbara Tudek, Amangeldy K Bissenbaev, Murat Saparbaev
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92963 (2014)
Apurinic/apyrimidinic (AP) endonucleases are key DNA repair enzymes involved in the base excision repair (BER) pathway. In BER, an AP endonuclease cleaves DNA at AP sites and 3'-blocking moieties generated by DNA glycosylases and/or oxidative damage.
Externí odkaz:
https://doaj.org/article/48b3c22a61b141b5940a12cda0947931
Autor:
Paulina Prorok, Christine Saint-Pierre, Didier Gasparutto, Olga S. Fedorova, Alexander A. Ishchenko, Hervé Leh, Malcolm Buckle, Barbara Tudek, Murat Saparbaev
Publikováno v:
PLoS ONE, Vol 8, Iss 7 (2013)
Externí odkaz:
https://doaj.org/article/0b191d82fb414bb09ca78d7a3923ba59