Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Paulina Marona"'
Autor:
Paulina Marona, Judyta Górka, Oliwia Kwapisz, Jolanta Jura, Janusz Rys, Robert M. Hoffman, Katarzyna Miekus
Publikováno v:
Cell Death and Disease, Vol 13, Iss 9, Pp 1-17 (2022)
Abstract Tyrosine kinase inhibitors (TKIs) are the most commonly used targeted therapeutics in clear-cell renal cell carcinoma (ccRCC); however, drug resistance limits their utility and can lead to tumor “flare-up” and progression. In this study,
Externí odkaz:
https://doaj.org/article/b9b7dba8693f4e029e928c26b9639543
Autor:
Oliwia Kwapisz, Judyta Górka, Agata Korlatowicz, Jerzy Kotlinowski, Agnieszka Waligórska, Paulina Marona, Natalia Pydyn, Jurek W. Dobrucki, Jolanta Jura, Katarzyna Miekus
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 3, p 1272 (2021)
Nonalcoholic fatty liver disease is defined as the accumulation of excessive fat in the liver in the absence of excessive alcohol consumption or any secondary cause. Although the disease generally remains asymptomatic, chronic liver inflammation lead
Externí odkaz:
https://doaj.org/article/705a06ddcb52407ba2a7786b755136d9
Autor:
Paulina Marona, Judyta Górka, Jerzy Kotlinowski, Marcin Majka, Jolanta Jura, Katarzyna Miekus
Publikováno v:
Cells, Vol 8, Iss 3, p 272 (2019)
C-Met tyrosine kinase receptor plays an important role under normal and pathological conditions. In tumor cells’ overexpression or incorrect activation of c-Met, this leads to stimulation of proliferation, survival and increase of motile activity.
Externí odkaz:
https://doaj.org/article/ee1bb0332efa4a1397865aa9080afc29
Autor:
Katarzyna Miekus, Jolanta Jura, Marcin Majka, Janusz Rys, Waclaw Wilk, Zofia Mazurek, Judyta Górka, Paulina Marona
Transient transfection with small interfering RNA (siRNA). Table 1. Sequences of primers Table 2. List of antibodies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57702ba3b09fa4c92d3f3e88795017ee
https://doi.org/10.1158/0008-5472.22414575.v1
https://doi.org/10.1158/0008-5472.22414575.v1
Autor:
Katarzyna Miekus, Jolanta Jura, Marcin Majka, Janusz Rys, Waclaw Wilk, Zofia Mazurek, Judyta Górka, Paulina Marona
Supplementary Figure S1. Downregulation level of MCPIP1 using siRNA or shRNA. Supplementary Figure S2. Effect of MCPIP1 downregulation level on tutor growth. Supplementary Figure S3. MCPIP1 upregulation in Caki-1 and Caki-2 cell lines and tutor growt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57f968f6d86177cf1375d2a7a183f29e
https://doi.org/10.1158/0008-5472.22414578
https://doi.org/10.1158/0008-5472.22414578
Autor:
Katarzyna Miekus, Jolanta Jura, Marcin Majka, Janusz Rys, Waclaw Wilk, Zofia Mazurek, Judyta Górka, Paulina Marona
Clear cell renal cell carcinoma (ccRCC) is the most common type of kidney cancer and it forms highly vascularized tumors. The monocyte endoribonuclease MCPIP1 negatively regulates inflammation by degrading mRNA encoding proinflammatory cytokines, suc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ec5065770b5e9b8f147a2f8d90c4c73
https://doi.org/10.1158/0008-5472.c.6509031.v1
https://doi.org/10.1158/0008-5472.c.6509031.v1
Autor:
Alicja Jozkowicz, Jozef Dulak, Bernarda Kazanowska, Aleksandra Urbanik, Oleksandr Yagensky, Bart Krist, Krzysztof Szade, Jacek Stepniewski, Magdalena Kusior, Magdalena Walawender, Agata Szade, Karolina Bukowska-Strakova, Agnieszka Loboda, Marta Seczynska, Mateusz Jez, Magdalena Kozakowska, Paulina Marona, Maciej Ciesla
Effect of valproic (VA, 100 mg/kg, injection every second day for three weeks) on tumors formed by CW9019-Luc aRMS cells transplanted subcutaneously to athymic nude mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63ee7a6ee8e86eb77c83f08039010baf
https://doi.org/10.1158/0008-5472.22409199
https://doi.org/10.1158/0008-5472.22409199
Autor:
Alicja Jozkowicz, Jozef Dulak, Bernarda Kazanowska, Aleksandra Urbanik, Oleksandr Yagensky, Bart Krist, Krzysztof Szade, Jacek Stepniewski, Magdalena Kusior, Magdalena Walawender, Agata Szade, Karolina Bukowska-Strakova, Agnieszka Loboda, Marta Seczynska, Mateusz Jez, Magdalena Kozakowska, Paulina Marona, Maciej Ciesla
Detailed description of methods used in the study with Supplementary Figures legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bd62be94e232a2fe101b669a85d4766
https://doi.org/10.1158/0008-5472.22409196
https://doi.org/10.1158/0008-5472.22409196
Data from Heme Oxygenase-1 Controls an HDAC4-miR-206 Pathway of Oxidative Stress in Rhabdomyosarcoma
Autor:
Alicja Jozkowicz, Jozef Dulak, Bernarda Kazanowska, Aleksandra Urbanik, Oleksandr Yagensky, Bart Krist, Krzysztof Szade, Jacek Stepniewski, Magdalena Kusior, Magdalena Walawender, Agata Szade, Karolina Bukowska-Strakova, Agnieszka Loboda, Marta Seczynska, Mateusz Jez, Magdalena Kozakowska, Paulina Marona, Maciej Ciesla
Rhabdomyosarcoma (RMS) is an aggressive soft tissue cancer characterized by disturbed myogenic differentiation. Here we report a role for the oxidative stress response factor HO-1 in progression of RMS. We found that HO-1 was elevated and its effecto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b64dbd49fd246afe343e777913d5303
https://doi.org/10.1158/0008-5472.c.6507723.v1
https://doi.org/10.1158/0008-5472.c.6507723.v1
Autor:
Katarzyna Miekus, Jolanta Jura, Janusz Rys, Jurek Dobrucki, Oliwia Kwapisz, Paulina Marona, Ewelina Pospiech, Agnieszka Waligórska, Judyta Górka
Publikováno v:
Oncogene
Epithelial-mesenchymal transition (EMT) refers to the acquisition of mesenchymal properties in cells participating in tumor progression. One hallmark of EMT is the increased level of active β-catenin, which can trigger the transcription of Wnt-speci