Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Paulina M. Wojnarowicz"'
Autor:
Paulina M. Wojnarowicz, Marta Garcia Escolano, Yun-Han Huang, Bina Desai, Yvette Chin, Riddhi Shah, Sijia Xu, Saurabh Yadav, Sergey Yaklichkin, Ouathek Ouerfelli, Rajesh Kumar Soni, John Philip, David C. Montrose, John H. Healey, Vinagolu K. Rajasekhar, William A. Garland, Jeremy Ratiu, Yuan Zhuang, Larry Norton, Neal Rosen, Ronald C. Hendrickson, Xi Kathy Zhou, Antonio Iavarone, Joan Massague, Andrew J. Dannenberg, Anna Lasorella, Robert Benezra
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-17 (2021)
Abstract ID proteins are helix-loop-helix (HLH) transcriptional regulators frequently overexpressed in cancer. ID proteins inhibit basic-HLH transcription factors often blocking differentiation and sustaining proliferation. A small-molecule, AGX51, t
Externí odkaz:
https://doaj.org/article/fcc94ce778e043e9991e8da7d30777e4
Autor:
Paulina M. Wojnarowicz, Raquel Lima e Silva, Masayuki Ohnaka, Sang Bae Lee, Yvette Chin, Anita Kulukian, Sung-Hee Chang, Bina Desai, Marta Garcia Escolano, Riddhi Shah, Marta Garcia-Cao, Sijia Xu, Rashmi Kadam, Yehuda Goldgur, Meredith A. Miller, Ouathek Ouerfelli, Guangli Yang, Tsutomu Arakawa, Steven K. Albanese, William A. Garland, Glenn Stoller, Jaideep Chaudhary, Larry Norton, Rajesh Kumar Soni, John Philip, Ronald C. Hendrickson, Antonio Iavarone, Andrew J. Dannenberg, John D. Chodera, Nikola Pavletich, Anna Lasorella, Peter A. Campochiaro, Robert Benezra
Publikováno v:
Cell Reports, Vol 29, Iss 1, Pp 62-75.e7 (2019)
Summary: Id helix-loop-helix (HLH) proteins (Id1–4) bind E protein bHLH transcription factors, preventing them from forming active transcription complexes that drive changes in cell states. Id proteins are primarily expressed during development to
Externí odkaz:
https://doaj.org/article/95d35ea0d3dd4fce8521d6c45f7d1b30
Autor:
John H. Healey, P. Edward Purdue, Steven R. Goldring, Dong Wang, Paulina M. Wojnarowicz, Jianbo Wu, Xin Wei, Alexander B. Christ, Vinagolu K. Rajasekhar, Chloe B. Horowitz, Melissa N. Zimel
In vitro flow cytometric analysis of the effects of folic acid on cellular uptake of the synthesized polymers. Flow cytometry demonstrated equivalent forward shifts in A, 4T1 cells stained with P-Alexa647 and B, 4T1 cells stained with P-Alexa647-FA.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c6a609838eb02ce796ee8e8bc08e194
https://doi.org/10.1158/1535-7163.22503879.v1
https://doi.org/10.1158/1535-7163.22503879.v1
Autor:
John H. Healey, P. Edward Purdue, Steven R. Goldring, Dong Wang, Paulina M. Wojnarowicz, Jianbo Wu, Xin Wei, Alexander B. Christ, Vinagolu K. Rajasekhar, Chloe B. Horowitz, Melissa N. Zimel
Distribution of clonal abnormalities in cell line 4T1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35fd8be1e11e8659b60e6eb79eacd4c4
https://doi.org/10.1158/1535-7163.22503870.v1
https://doi.org/10.1158/1535-7163.22503870.v1
Autor:
Feven Tameire, Paulina M. Wojnarowicz, Sho Fujisawa, Sharon Huang, Owen Reilly, Crissy Dudgeon, Nicholas Collette, Jeremy Drees, Kathryn Bieging-Rolett, Takashi O Kangas, Weiyu Zhang, Maria Fumagalli, Iman Dewji, Yunfang Li, Anissa SH Chan, Xiaohong Qiu, Ben Harrison, Ashley LaCayo, Kirk A. Staschke, Alan C. Rigby, Savithri Ramurthy, Eric S. Lightcap, David Surguladze, Nandita Bose
Publikováno v:
Blood Cancer Discovery. 4:A30-A30
The integrated stress response (ISR) is an adaptive signaling pathway that cells utilize to respond to a wide range of extrinsic and intrinsic stresses, many of which are important for tumorigenesis. Activation of ISR plays a dual role in cell fate d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cee5d979200d35a8181e50a4a9612733
https://doi.org/10.1158/2643-3249.aml23-a30
https://doi.org/10.1158/2643-3249.aml23-a30
Autor:
Sijia Xu, Antonio Iavarone, Andrew J. Dannenberg, Robert Benezra, John H. Healey, Vinagolu K. Rajasekhar, William A. Garland, Marta Garcia Escolano, Ouathek Ouerfelli, Yun-Han Huang, Yvette Chin, David C. Montrose, Riddhi Shah, Xi Kathy Zhou, Anna Lasorella, John Philip, Bina Desai, Larry Norton, Rajesh K. Soni, Ronald C. Hendrickson, Neal Rosen, Joan Massagué, Paulina M. Wojnarowicz
SummaryId proteins are helix-loop-helix (HLH) transcriptional regulators frequently overexpressed in cancer. Id proteins inhibit basic HLH transcription factors through protein-protein interactions, often inhibiting differentiation and sustaining pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f625321fdd98b3d30b8d9cdee8df39e7
https://doi.org/10.1101/2020.01.06.894840
https://doi.org/10.1101/2020.01.06.894840
Autor:
Bina Desai, Nikola P. Pavletich, Anna Lasorella, Yehuda Goldgur, Ronald C. Hendrickson, Steven K. Albanese, Ouathek Ouerfelli, Rashmi Kadam, Guangli Yang, Anita Kulukian, Meredith A. Miller, Andrew J. Dannenberg, Marta Garcia-Cao, Sijia Xu, Peter A. Campochiaro, Riddhi Shah, Sung Hee Chang, Marta Garcia Escolano, Paulina M. Wojnarowicz, John Philip, John D. Chodera, Rajesh K. Soni, Yvette Chin, Glenn L. Stoller, Masayuki Ohnaka, William A. Garland, Jaideep Chaudhary, Antonio Iavarone, Tsutomu Arakawa, Robert Benezra, Raquel Lima e Silva, Sang Bae Lee, Larry Norton
Publikováno v:
Cell reports
Cell Reports, Vol 29, Iss 1, Pp 62-75.e7 (2019)
Cell Reports, Vol 29, Iss 1, Pp 62-75.e7 (2019)
SUMMARY Id helix-loop-helix (HLH) proteins (Id1–4) bind E protein bHLH transcription factors, preventing them from forming active transcription complexes that drive changes in cell states. Id proteins are primarily expressed during development to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c853a050cb04788af4ee4ab303e41007
https://doi.org/10.1016/j.celrep.2019.08.073
https://doi.org/10.1016/j.celrep.2019.08.073
Autor:
Karen Gambaro, Paulina M. Wojnarowicz, Michael C.J. Quinn, Jean Sébastien Ripeau, Mario Chevrette, Manon de Ladurantaye, Anne Marie Mes-Masson, Ann M. Killary, Suzanna L. Arcand, Elaine C. Davis, Véronique Barrès, Josée N. Lavoie, Patricia N. Tonin, Diane Provencher
Publikováno v:
Molecular Oncology. 7:513-530
Previous studies have implicated vestigial like 3 (VGLL3), a chromosome 3p12.3 gene that encodes a putative transcription co‐factor, as a candidate tumor suppressor gene (TSG) in high‐grade serous ovarian carcinomas (HGSC), the most common type o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f204e85871156f8fdcbafe65dd5cca2b
https://doi.org/10.1016/j.molonc.2012.12.006
https://doi.org/10.1016/j.molonc.2012.12.006
Autor:
John D. Chodera, Antonio Iavarone, Ouathek Ouerfelli, William A. Garland, Larry Norton, Xi Kathy Zhou, Nikola P. Pavletich, Robert Benezra, Guangli Yang, Steven K. Albanese, Bina Desai, Sijia Xu, Meredith A. Miller, Yvette Chin, Marta Garcia-Cao, Yehuda Goldgur, Anna Lasorella, Andrew J. Dannenberg, John Philip, Rajesh K. Soni, Paulina M. Wojnarowicz, Sang Bae Lee, Ronald C. Hendrickson, Neal Rosen, Jaideep Chaudhary
Publikováno v:
Cancer Research. 77:4975-4975
The Id family of helix-loop-helix (HLH) proteins, Id1, Id2, Id3 and Id4, play a critical role in inhibiting differentiation during mammalian embryogenesis. They function in part by sequestering ubiquitously expressed E protein bHLH transcription fact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f7797be34cab4f7cb77594e6efdbc67
https://doi.org/10.1158/1538-7445.am2017-4975
https://doi.org/10.1158/1538-7445.am2017-4975
Autor:
Courtney Coker, Venkatraman E. Seshan, Riddhi Shah, Robert Benezra, Elizabeth A. Comen, Paulina M. Wojnarowicz, Larry Norton
Publikováno v:
NPJ Breast Cancer
We have previously shown a novel antimetastatic role for neutrophils in the premetastatic lung of mice in models of breast cancer. Here we expand on those findings in the context of human breast cancer. We assessed the cytotoxicity of neutrophils fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4b99e1a32a5182b6e4a1b5ef31c7b20
http://europepmc.org/articles/PMC5515342
http://europepmc.org/articles/PMC5515342