Zobrazeno 1 - 10 of 50 pro vyhledávání: '"Paulina M Kowalewska"'
1
Akademický článek
Spectroscopy detects skeletal muscle microvascular dysfunction during onset of sepsis in a rat fecal peritonitis model
Autor: Paulina M. Kowalewska, Justin E. Piazza, Stephanie L. Milkovich, Richard J. Sové, Lin Wang, Shawn N. Whitehead, Christopher G. Ellis
Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Sepsis is a dysregulated host inflammatory response to infection potentially leading to life-threatening organ dysfunction. The objectives of this study were to determine whether early microvascular dysfunction (MVD) in skeletal muscle can b
Externí odkaz: https://doaj.org/article/2882ed0426464ea382735ea599cf8c8a
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3
Akademický článek
Role and Molecular Mechanisms of Pericytes in Regulation of Leukocyte Diapedesis in Inflamed Tissues
Autor: Paulina Rudziak, Christopher G. Ellis, Paulina M. Kowalewska
Publikováno v: Mediators of Inflammation, Vol 2019 (2019)
Leukocyte recruitment is a hallmark of the inflammatory response. Migrating leukocytes breach the endothelium along with the vascular basement membrane and associated pericytes. While much is known about leukocyte-endothelial cell interactions, the m
Externí odkaz: https://doaj.org/article/b32b6cea9a7442b08a9b31e33074ab57
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4
Genetic ablation of smooth muscle KIR2.1 is inconsequential to the function of mouse cerebral arteries
Autor: Paulina M Kowalewska, Jacob Fletcher, William F Jackson, Suzanne E Brett, Michelle SM Kim, Galina Yu Mironova, Nadia Haghbin, David M Richter, Nathan R Tykocki, Mark T Nelson, Donald G Welsh
Publikováno v: Journal of Cerebral Blood Flow & Metabolism. 42:1693-1706
Cerebral blood flow is a finely tuned process dependent on coordinated changes in arterial tone. These changes are strongly tied to smooth muscle membrane potential and inwardly rectifying K+ (KIR) channels are thought to be a key determinant. To elu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fd28ec5763eec31b6de98cd61798c95d
https://doi.org/10.1177/0271678x221093432
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9
Spectroscopy detects skeletal muscle microvascular dysfunction during onset of sepsis in a rat fecal peritonitis model
Autor: Paulina M, Kowalewska, Justin E, Piazza, Stephanie L, Milkovich, Richard J, Sové, Lin, Wang, Shawn N, Whitehead, Christopher G, Ellis
Publikováno v: Scientific reports. 12(1)
Sepsis is a dysregulated host inflammatory response to infection potentially leading to life-threatening organ dysfunction. The objectives of this study were to determine whether early microvascular dysfunction (MVD) in skeletal muscle can be detecte
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0147273232e8c5c2ea00fc8293bfc2d2
https://pubmed.ncbi.nlm.nih.gov/35428849
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10
Akademický článek
Syndecan-1 in the mouse parietal peritoneum microcirculation in inflammation.
Autor: Paulina M Kowalewska, Amanda L Patrick, Alison E Fox-Robichaud
Publikováno v: PLoS ONE, Vol 9, Iss 9, p e104537 (2014)
BACKGROUND: The heparan sulfate proteoglycan syndecan-1 (CD138) was shown to regulate inflammatory responses by binding chemokines and cytokines and interacting with adhesion molecules, thereby modulating leukocyte trafficking to tissues. The objecti
Externí odkaz: https://doaj.org/article/019b55a807ef4af39874ae98f16edad8
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