Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Paulina Krzyszczyk"'
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Macrophages play key roles in all phases of adult wound healing, which are inflammation, proliferation, and remodeling. As wounds heal, the local macrophage population transitions from predominantly pro-inflammatory (M1-like phenotypes) to anti-infla
Externí odkaz:
https://doaj.org/article/c38e0b8375264cc4b70358d5da60c078
Autor:
Rene S. Schloss, Yixin Meng, Andre F. Palmer, Kishan Patel, Ivan S. Pires, Martin L. Yarmush, Suneel Kumar, Maurice D. O'Reggio, Hwan June Kang, Francois Berthiaume, Paulina Krzyszczyk
Publikováno v:
Wound Repair and Regeneration. 28:493-505
Nonhealing wounds possess elevated numbers of pro-inflammatory M1 macrophages, which fail to transition to anti-inflammatory M2 phenotypes that promote healing. Hemoglobin (Hb) and haptoglobin (Hp) proteins, when complexed (Hb-Hp), can elicit M2-like
Autor:
Rene S. Schloss, Yixin Meng, Maurice D. O'Reggio, Francois Berthiaume, Alison Acevedo, Martin L. Yarmush, Ioannis P. Androulakis, Andre F. Palmer, Kishan Patel, Kristopher Emil Richardson, Paulina Krzyszczyk
Publikováno v:
TECHNOLOGY. :84-97
Chronic skin wounds are hypoxic and are stalled in a pro-inflammatory state. Hemoglobin (Hb)-based oxygen carriers have shown potential in increasing oxygen delivery to aid wound healing. Macrophages also take up Hb, thus altering their phenotype and
Autor:
Joseph W. Freeman, Renea Faulknor, Francois Berthiaume, Melissa A. Olekson, Paulina Krzyszczyk, Emmanuel C. Ekwueme
Publikováno v:
TECHNOLOGY. :81-86
The transition of macrophages from the pro-inflammatory M1 to the anti-inflammatory M2 phenotype is crucial for the progression of normal wound healing. Persistent M1 macrophages within the injury site may lead to an uncontrolled macrophage-mediated
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Frontiers in Physiology
Frontiers in Physiology
Macrophages play key roles in all phases of adult wound healing, which are inflammation, proliferation, and remodeling. As wounds heal, the local macrophage population transitions from predominantly pro-inflammatory (M1-like phenotypes) to anti-infla
Publikováno v:
Nano LIFE. :1750002
An exuberant inflammatory response may exacerbate the primary tissue damage caused by injuries to the skin due to burns, surgery, excessive pressure, and other etiologies, thus increasing the time to heal. We hypothesized that application of factors
When plated onto a substrate, cells spread. Many cell types, including smooth muscle cells and fibroblasts, spread more effectively on stiffer substrates, and a simple empirical relationship has been determined that relates a cell's spread area to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95ea188a611e2cc3ad1d3b8321de74c9
https://europepmc.org/articles/PMC3218332/
https://europepmc.org/articles/PMC3218332/