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pro vyhledávání: '"Paulina Flores-Carrillo"'
Autor:
Paulina Flores-Carrillo, Alfredo Téllez-Valencia, Lilián Yépez-Mulia, José Miguel Velázquez-López, Rafael Castillo, Rocío Nieto-Meneses, Alicia Hernández-Campos
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 26:4377-4381
The present work reports the synthesis and biological activity of a series of 14 benzimidazole derivatives designed to act on the enzyme triosephosphate isomerase of Trypanosoma cruzi (TcTIM). This enzyme is involved in the metabolism of glucose, the
Autor:
Rafael Castillo, Alicia Hernández-Campos, Rodrigo Aguayo-Ortiz, Paulina Flores-Carrillo, Pedro Josué Trejo-Soto, José Miguel Velázquez-López, Lilián Yépez-Mulia
Publikováno v:
European journal of medicinal chemistry. 137
A series of twelve new 2-(methylthio)-1 H -benzimidazole-5-carboxamide derivatives ( 1 − 12 ) were synthesized and their antiparasitic activity was tested in vitro against Giardia intestinalis , Trichomonas vaginalis and Entamoeba histolytica . Exp