Výsledky vyhledávání - "Paulina Ampomah"

Akademický článek

In vitro and In vivo antimalarial activities of Avicennia africana P. Beauv. (Avicenniaceae) ethanolic leaf extract

Autor: Mustapha A. Ahmed, Elvis O. Ameyaw, Francis Ackah-Armah, Desmond O. Acheampong, Benjamin Amoani, Paulina Ampomah, Emmanuel A. Adakudugu, Christian K. Adokoh

Publikováno v: Journal of Traditional and Complementary Medicine, Vol 12, Iss 4, Pp 391-401 (2022)

Background: The emergence of widespread drug-resistant strains of the malaria parasites militates against strives for more potent antimalarial drugs. Aim: The present study evaluated the antimalarial activity of A. africana ethanolic crude extract in

Externí odkaz: https://doaj.org/article/37d8f27a7ba849668f25a69314fe5d3e

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Akademický článek

Afucosylated Plasmodium falciparum-specific IgG is induced by infection but not by subunit vaccination

Autor: Mads Delbo Larsen, Mary Lopez-Perez, Emmanuel Kakra Dickson, Paulina Ampomah, Nicaise Tuikue Ndam, Jan Nouta, Carolien A. M. Koeleman, Agnes L. Hipgrave Ederveen, Benjamin Mordmüller, Ali Salanti, Morten Agertoug Nielsen, Achille Massougbodji, C. Ellen van der Schoot, Michael F. Ofori, Manfred Wuhrer, Lars Hviid, Gestur Vidarsson

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)

Here, Larsen et al. describe differences in Fc fucosylation of P. falciparum PfEMP1-specific IgG produced in response to natural infection versus VAR2CSA-type subunit vaccination, which leads to differences in the ability to induce FcγRIIIa-dependen

Externí odkaz: https://doaj.org/article/a9888fc047054d7cb375efcf290854a4

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Akademický článek

Characterization of putative drug resistant biomarkers in Plasmodium falciparum isolated from Ghanaian blood donors

Autor: Enoch Aninagyei, Kwabena Obeng Duedu, Tanko Rufai, Comfort Dede Tetteh, Margaretta Gloria Chandi, Paulina Ampomah, Desmond Omane Acheampong

Publikováno v: BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-11 (2020)

Abstract Background Plasmodium falciparum parasites, which could harbour anti-malaria drug resistance genes, are commonly detected in blood donors in malaria-endemic areas. Notwithstanding, anti-malaria drug resistant biomarkers have not been charact

Externí odkaz: https://doaj.org/article/846e53e010644e40ba74aeac5351edb2

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Immunological, haematological, and clinical attributes of rural and urban malaria: a case–control study in Ghana

Autor: Paulina Ampomah, Patrick Adu, Desmond Omane Acheampong, Kwabena O. Duedu, Enoch Aninagyei

Publikováno v: J Parasit Dis

To compare clinical presentations, haematological and immunological parameters in urban and rural malaria patients. Clinically suspected malaria patients, resident in either rural or urban communities, were selected from seven health facilities in th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db8aafd14eaf4011f85168057c22f159
https://doi.org/10.1007/s12639-021-01363-4

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Effect of Asymptomatic Plasmodium falciparum Parasitaemia on Platelets Thrombogenicity in Blood Donors

Autor: Alexander Egyir-Yawson, Tanko Rufai, Godwin Kwakye-Nuako, Enoch Aninagyei, Desmond Omane Acheampong, Patrick Adu, Paulina Ampomah

Publikováno v: Indian J Hematol Blood Transfus

Currently, blood donors in Ghana are not screened for malaria parasites. Therefore, this study assessed platelet thrombogenicity in blood donors infected asymptomatically with Plasmodium falciparum and the relationship between tumour necrosis factor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d037739d6123cc4d08fa4232f359f9dc
https://doi.org/10.1007/s12288-020-01390-w

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Afucosylated Plasmodium falciparum-specific IgG is induced by infection but not by subunit vaccination

Autor: Paulina Ampomah, Lars Hviid, Mads Delbo Larsen, Morten Nielsen, Emmanuel K. Dickson, Jan Nouta, Nicaise Tuikue Ndam, Carolien A. M. Koeleman, Ali Salanti, Benjamin Mordmüller, Agnes L. Hipgrave Ederveen, Michael F. Ofori, Achille Massougbodji, Mary Lopez-Perez, Manfred Wuhrer, Gestur Vidarsson, C. Ellen van der Schoot

Publikováno v: Nature Communications, 12, 1
Nature Communications, 12
Nature Communications, 12(1). NATURE PORTFOLIO
Nature Communications
Larsen, M D, Lopez-Perez, M, Dickson, E K, Ampomah, P, Tuikue Ndam, N, Nouta, J, Koeleman, C A M, Ederveen, A L H, Mordmüller, B, Salanti, A, Nielsen, M A, Massougbodji, A, van der Schoot, C E, Ofori, M F, Wuhrer, M, Hviid, L & Vidarsson, G 2021, ' Afucosylated Plasmodium falciparum-specific IgG is induced by infection but not by subunit vaccination ', Nature Communications, vol. 12, 5838 . https://doi.org/10.1038/s41467-021-26118-w
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Nature Communications, 12, 1. Nature Publishing Group

Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family members mediate receptor- and tissue-specific sequestration of infected erythrocytes (IEs) in malaria. Antibody responses are a central component of naturally acquired malaria immun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7382c2e64633785034e56577f9beb820
https://dspace.library.uu.nl/handle/1874/425173

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Characterization of putative drug resistant biomarkers in Plasmodium falciparum isolated from Ghanaian blood donors

Autor: Desmond Omane Acheampong, Enoch Aninagyei, Margaretta Gloria Chandi, Kwabena O. Duedu, Tanko Rufai, Paulina Ampomah, Comfort Dede Tetteh

Publikováno v: BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-11 (2020)
BMC Infectious Diseases

Background Plasmodium falciparum parasites, which could harbour anti-malaria drug resistance genes, are commonly detected in blood donors in malaria-endemic areas. Notwithstanding, anti-malaria drug resistant biomarkers have not been characterized in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1df5e428f4fde6e776558f3e2305d2b2
https://doi.org/10.1186/s12879-020-05266-2

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Bispecific Antibodies (bsAbs): Promising Immunotherapeutic Agents for Cancer Therapy

Autor: Isaac Dadzie, Deasmond O. Acheampong, Francis A. Ackah, Ernest Amponsah Asiamah, Paulina Ampomah, Christian K. Adokoh, Daniel S. Agyirifor

Publikováno v: Protein & Peptide Letters. 24:456-465

Antibodies have become the preferred therapeutic treatment option for cancers. Antibody therapy is associated with low toxic profile and specific in its activity, unlike chemotherapy and radiotherapy. Types of tumor are known to express multiple rece

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8388bd2759c1dba64345519549094a62
https://doi.org/10.2174/0929866524666170120095128

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An Ethnomedicinal Survey of Plants Used To Treat Malaria in the Central Region of Ghana

Autor: Elvis OforiAmeyaw, Kobina Yankson, Hugh Komla Akotoye, Paulina Ampomah

Publikováno v: The Journal of Phytopharmacology. 6:107-114

Herbal medicines form a major component of traditional medicine in Africa because they are perceived to be efficacious and safe. The study aimed at investigating anti-malarial plants used by the indigenous people in the Central Region of Ghana. The s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8cfeaeb76c5365495f89943d1aa6c029
https://doi.org/10.31254/phyto.2017.6208

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