Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Paulina A Hawkins"'
Autor:
Cebile Lekhuleni, Kedibone Ndlangisa, Rebecca A. Gladstone, Sopio Chochua, Benjamin J. Metcalf, Yuan Li, Jackie Kleynhans, Linda de Gouveia, Scott Hazelhurst, Ana D. S. Ferreira, Happy Skosana, Sibongile Walaza, Vanessa Quan, Susan Meiring, Paulina A. Hawkins, Lesley McGee, Stephen D. Bentley, Cheryl Cohen, Stephanie W. Lo, Anne von Gottberg, Mignon du Plessis
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Invasive pneumococcal disease (IPD) due to non-vaccine serotypes after the introduction of pneumococcal conjugate vaccines (PCV) remains a global concern. This study used pathogen genomics to evaluate changes in invasive pneumococcal lineage
Externí odkaz:
https://doaj.org/article/428323113fd04185bfd8dcf4843186a7
Autor:
Richard E Haaland, Paulina A Hawkins, Jesus Salazar-Gonzalez, Amber Johnson, Amanda Tichacek, Etienne Karita, Olivier Manigart, Joseph Mulenga, Brandon F Keele, George M Shaw, Beatrice H Hahn, Susan A Allen, Cynthia A Derdeyn, Eric Hunter
Publikováno v:
PLoS Pathogens, Vol 5, Iss 1, p e1000274 (2009)
The HIV-1 epidemic in sub-Saharan Africa is driven largely by heterosexual transmission of non-subtype B viruses, of which subtypes C and A are predominant. Previous studies of subtype B and subtype C transmission pairs have suggested that a single v
Externí odkaz:
https://doaj.org/article/cd718ab0396f4bf491cbdcefb4764d41
Autor:
Rebecca A. Gladstone, Stephanie W. Lo, John A. Lees, Nicholas J. Croucher, Andries J. van Tonder, Jukka Corander, Andrew J. Page, Pekka Marttinen, Leon J. Bentley, Theresa J. Ochoa, Pak Leung Ho, Mignon du Plessis, Jennifer E. Cornick, Brenda Kwambana-Adams, Rachel Benisty, Susan A. Nzenze, Shabir A. Madhi, Paulina A. Hawkins, Dean B. Everett, Martin Antonio, Ron Dagan, Keith P. Klugman, Anne von Gottberg, Lesley McGee, Robert F. Breiman, Stephen D. Bentley
Publikováno v:
EBioMedicine, Vol 43, Iss , Pp 338-346 (2019)
Background: Pneumococcal conjugate vaccines have reduced the incidence of invasive pneumococcal disease, caused by vaccine serotypes, but non-vaccine-serotypes remain a concern. We used whole genome sequencing to study pneumococcal serotype, antibiot
Externí odkaz:
https://doaj.org/article/4f78456e71ec429c89ae26a2c712815f
Autor:
Stephanie W Lo, Kate Mellor, Robert Cohen, Alba Redin Alonso, Sophie Belman, Narender Kumar, Paulina A Hawkins, Rebecca A Gladstone, Anne von Gottberg, Balaji Veeraraghavan, K L Ravikumar, Rama Kandasamy, Sir Andrew J Pollard, Samir K Saha, Godfrey Bigogo, Martin Antonio, Brenda Kwambana-Adams, Shaper Mirza, Sadia Shakoor, Imran Nisar, Jennifer E Cornick, Deborah Lehmann, Rebecca L Ford, Betuel Sigauque, Paul Turner, Jennifer Moïsi, Stephen K Obaro, Ron Dagan, Idrissa Diawara, Anna Skoczyńska, Hui Wang, Philip E Carter, Keith P Klugman, Gail Rodgers, Robert F Breiman, Lesley McGee, Stephen D Bentley, Carmen Muñoz-Almagro, Emmanuelle Varon, Abdullah Brooks, Alejandra Corso, Alexander Davydov, Alison Maguire, Anmol Kiran, Benild Moiane, Bernard Beall, Chunjiang Zhao, David Aanensen, Dean Everett, Diego Faccone, Ebenezer Foster-Nyarko, Ebrima Bojang, Ekaterina Egorova, Elena Voropaeva, Eric Sampane-Donkor, Ewa Sadowy, Geetha Nagaraj, Helio Mucavele, Houria Belabbès, Naima Elmdaghri, Jennifer Verani, Jeremy Keenan, John Lees, Jyothish N Nair Thulasee Bhai, Kedibone Ndlangisa, Khalid Zerouali, Leon Bentley, Leonid Titov, Linda De Gouveia, Maaike Alaerts, Margaret Ip, Maria Cristina de Cunto Brandileone, Md Hasanuzzaman, Metka Paragi, Michele Nurse-Lucas, Mignon du Plessis, Mushal Ali, Nicholas Croucher, Nicole Wolter, Noga Givon-Lavi, Nurit Porat, Özgen Köseoglu Eser, Pak-Leung Ho, Patrick Eberechi Akpaka, Paula Gagetti, Peggy-Estelle Tientcheu, Pierra Law, Rachel Benisty, Rafal Mostowy, Roly Malaker, Samanta Cristine Grassi Almeida, Sanjay Doiphode, Shabir Madhi, Shamala Devi Sekaran, Stuart Clarke, Somporn Srifuengfung, Susan Nzenze, Tamara Kastrin, Theresa Ochoa, Waleria Hryniewicz, Yulia Urban
Publikováno v:
The Lancet Microbe. 3:e735-e743
Background Serotype 24F is one of the emerging pneumococcal serotypes after the introduction of pneumococcal conjugate vaccine (PCV). We aimed to identify lineages driving the increase of serotype 24F in France and place these findings into a global
Autor:
Emma K, Accorsi, Sopio, Chochua, Heidi L, Moline, Matt, Hall, Adam L, Hersh, Samir S, Shah, Amadea, Britton, Paulina A, Hawkins, Wei, Xing, Jennifer, Onukwube Okaro, Lindsay, Zielinski, Lesley, McGee, Stephanie, Schrag, Adam L, Cohen
Publikováno v:
MMWR. Morbidity and Mortality Weekly Report. 71:1169-1173
In May 2022, CDC learned of three children in California hospitalized concurrently for brain abscess, epidural empyema, or subdural empyema caused by Streptococcus intermedius. Discussions with clinicians in multiple states raised concerns about a po
Autor:
Sophie Belman, Sona Soeng, Chansovannara Soputhy, Rebecca Gladstone, Paulina A. Hawkins, Robert F. Breiman, Lesley McGee, Stephen D. Bentley, Stephanie W. Lo, Paul Turner
Publikováno v:
Microbial Genomics. 8
Streptococcus pneumoniae (the pneumococcus) is a leading cause of childhood mortality globally and in Cambodia. It is commensal in the human nasopharynx, occasionally resulting in invasive disease. Monitoring population genetic shifts, characterized
Autor:
Kedibone M, Ndlangisa, Mignon, du Plessis, Stephanie, Lo, Linda, de Gouveia, Chrispin, Chaguza, Martin, Antonio, Brenda, Kwambana-Adams, Jennifer, Cornick, Dean B, Everett, Ron, Dagan, Paulina A, Hawkins, Bernard, Beall, Alejandra, Corso, Samanta Cristine, Grassi Almeida, Theresa J, Ochoa, Stephen, Obaro, Sadia, Shakoor, Eric S, Donkor, Rebecca A, Gladstone, Pak Leung, Ho, Metka, Paragi, Sanjay, Doiphode, Somporn, Srifuengfung, Rebecca, Ford, Jennifer, Moïsi, Samir K, Saha, Godfrey, Bigogo, Betuel, Sigauque, Özgen Köseoglu, Eser, Naima, Elmdaghri, Leonid, Titov, Paul, Turner, K L Ravi, Kumar, Rama, Kandasamy, Ekaterina, Egorova, Margaret, Ip, Robert F, Breiman, Keith P, Klugman, Lesley, McGee, Stephen D, Bentley, Anne, von Gottberg, The Global Pneumococcal Sequencing Consortium
Publikováno v:
Microbial genomics. 8(4)
Pneumococcal serotype 35B is an important non-conjugate vaccine (non-PCV) serotype. Its continued emergence, post-PCV7 in the USA, was associated with expansion of a pre-existing 35B clone (clonal complex [CC] 558) along with post-PCV13 emergence of
Autor:
Ekaterina Egorova, Narender Kumar, Rebecca A. Gladstone, Yulia Urban, Elena Voropaeva, A.V. Chaplin, Elena Rumiantseva, T. S. Svistunova, Paulina A. Hawkins, Keith P. Klugman, Robert F. Breiman, Lesley McGee, Stephen D. Bentley, Stephanie W. Lo
Invasive pneumococcal disease remains one of the leading causes of morbidity and mortality worldwide. In Russia, 13- valent pneumococcal conjugate vaccine (PCV13) was introduced into the childhood immunization programme nationwide in 2014. As part of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc9b8408cd9c01297cc14ee42fd397cc
http://hdl.handle.net/10852/99345
http://hdl.handle.net/10852/99345
Autor:
Alba Redin Alonso, Imran Nisar, Betuel Sigaúque, Kate Mellor, Shaper Mirza, Lesley McGee, Hui Wang, Sophie Belman, Rebecca Ford, Gail L Rodgers, Paulina A. Hawkins, Rebecca A. Gladstone, Jennifer E. Cornick, Anne von Gottberg, Emmanuelle Varon, Balaji Veeraraghavan, Robert M. Cohen, Philip E. Carter, Ron Dagan, Stephanie W. Lo, Anna Skoczynska, Sadia Shakoor, Stephen K. Obaro, Martin Antonio, Godfrey Bigogo, Deborah Lehmann, Rama Kandasamy, Andrew J. Pollard, Stephen D. Bentley, Samir K. Saha, Jennifer C. Moïsi, K L Ravikumar, Paul Turner, Carmen Munoz Almagro, Brenda Kwambana-Adams, Keith P. Klugman, Robert F. Breiman, Narender Kumar, Naima Elmdaghri
SummaryBackgroundPneumococcal Conjugate Vaccine (PCV) which targets up to 13 serotypes of Streptococcus pneumoniae is very effective at reducing disease in young children; however, rapid increases in replacement with non-PCV serotypes remains a conce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17aa21404852d6815a25b2d37219de1c
https://doi.org/10.1101/2021.11.24.21266813
https://doi.org/10.1101/2021.11.24.21266813
Autor:
Lesley McGee, Robert F. Breiman, Keith P. Klugman, Brandileone Mc, Stephanie W. Lo, Ana Paula Cassiolato, Rebecca A. Gladstone, Paulina A. Hawkins, Samanta Cristine Grassi Almeida, Stephen D. Bentley
Publikováno v:
Microbial Genomics. 7
In 2010, Brazil introduced the 10-valent pneumococcal conjugate vaccine (PCV10) into the national children’s immunization programme. This study describes the genetic characteristics of invasive Streptococcus pneumoniae isolates before and after PCV