Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Pauliina Niemelä"'
Publikováno v:
Microchimica Acta. 172:25-29
A single-labeled peptide probe for measuring peptide phosphorylation status was developed by using a phosphate sensitive terbium chelate. The activity of Abl protein tyrosine kinase and T-cell protein Tyrosine phosphatase (TC PTP) was monitored in re
Autor:
Markus Graefen, Andreas Erbersdobler, Thomas Steuber, Michael W. Kattan, Kim Pettersson, Pauliina Niemelä, Alexander Haese, Hartwig Huland, K.-H. Felix Chun, Hans Lilja
Publikováno v:
The Prostate. 63:13-18
BACKGROUND. We investigated the association of different subfractions of prostate specific antigen (PSA) and human glandular kallikrein 2 (hK2), such as total PSA (tPSA), complexed PSA (cPSA), free PSA (fPSA), "single-chain Intact fPSA" (fPSA-I), "mu
Publikováno v:
Journal of immunological methods. 369(1-2)
Total levels of circulating prostate-specific antigen (tPSA) are strongly associated with prostate cancer (PCa) risk and outcome but benign prostate disease is the most frequent cause of a moderately elevated PSA level. Free PSA (fPSA) forms are inde
Autor:
Kim Pettersson, Pauliina Niemelä, Ville Väisänen, Tommi Viitanen, Kalle Alanen, Mari T. Peltola, Martti Nurmi
Publikováno v:
Urology. 77(4)
To measure the concentration levels of free prostate-specific antigen (PSA) isoforms in patients with prostate cancer selected for curative treatment using radical prostatectomy and to study the association between the isoforms and the pathologic can
Publikováno v:
Analytical biochemistry. 375(1)
The control of cell death is an intricate process involving a multitude of intracellular modulators. Among these molecules, the caspases have a central role and have become an interesting group of enzymes in the current pharmaceutical industry. We ha
Autor:
Pauliina Niemelä, Heidi Appelblom, Michael Pasternack, Jussi Nurmi, Timo Lövgren, Kai E Penttilä, Tero Soukka
Publikováno v:
Journal of biomolecular screening. 12(6)
A homogeneous high-throughput screening method based on time-resolved fluorescence resonance energy transfer (TR-FRET) for the measurement of calcium-dependent multimerization of an EF-hand protein, sorcin, is described. The assay is based on a speci
Autor:
Ulf-Håkan Stenman, Kim Pettersson, Jari Leinonen, Janita Lövgren, Heli Nevanlinna, L. Bocchi, Pauliina Niemelä
Publikováno v:
Journal of immunological methods. 289(1-2)
Prostate specific antigen (PSA) is the most important marker for prostate cancer. Antibodies against minor variants of PSA may be useful in the development of novel diagnostic tests for prostate cancer, but it has been difficult to produce such antib
Publikováno v:
Clinical chemistry. 48(8)
The proteome of the serine protease prostate-specific antigen (PSA) and its enzymatic properties have been clarified only recently. We have developed a specific and sensitive method for the measurement of active PSA and used it to measure proPSA in b