Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Paulette Legendre"'
Autor:
Caterina Casari, Remi Favier, Paulette Legendre, Alexandre Kauskot, Frederic Adam, Veronique Picard, Peter J. Lenting, Cecile V. Denis, Valerie Proulle
Publikováno v:
Therapeutic Advances in Hematology, Vol 13 (2022)
This report describes the first case of splenic injury in a patient with p.V1316M-associated von Willebrand disease type 2B (VWD2B) with chronic thrombocytopenia, successfully treated with nonoperative management including von Willebrand factor (VWF)
Externí odkaz:
https://doaj.org/article/f46a35a8466e49af9e0fca1439be9097
Autor:
Annabelle Dupont, Christelle Soukaseum, Mathilde Cheptou, Frédéric Adam, Thomas Nipoti, Marc-Damien Lourenco-Rodrigues, Paulette Legendre, Valérie Proulle, Antoine Rauch, Charlotte Kawecki, Marijke Bryckaert, Jean-Philippe Rosa, Camille Paris, Catherine Ternisien, Pierre Boisseau, Jenny Goudemand, Delphine Borgel, Dominique Lasne, Pascal Maurice, Peter J. Lenting, Cécile V. Denis, Sophie Susen, Alexandre Kauskot
Publikováno v:
Haematologica, Vol 104, Iss 12 (2019)
Patients with type 2B von Willebrand disease (vWD) (caused by gain-of-function mutations in the gene coding for von Willebrand factor) display bleeding to a variable extent and, in some cases, thrombocytopenia. There are several underlying causes of
Externí odkaz:
https://doaj.org/article/c6a2a981946540fc902c3cbea7dc27d8
Autor:
Nikolett Wohner, Vincent Muczynski, Amel Mohamadi, Paulette Legendre, Valérie Proulle, Gabriel Aymé, Olivier D. Christophe, Peter J. Lenting, Cécile V. Denis, Caterina Casari
Publikováno v:
Haematologica, Vol 103, Iss 4 (2018)
Previously, we found that LDL-receptor related protein-1 on macrophages mediated shear stress-dependent clearance of von Willebrand factor. In control experiments, however, we observed that von Willebrand factor also binds to macrophages independentl
Externí odkaz:
https://doaj.org/article/262372d980554845a2e76f26c83ee609
Autor:
Eliane Berrou, Alexandre Kauskot, Frédéric Adam, Amélie Harel, Paulette Legendre, Cécile Lavenu Bombled, Chantal Rothschild, Nicolas Prevost, Olivier D Christophe, Peter J Lenting, Cécile V Denis, Jean-Philippe Rosa, Marijke Bryckaert
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0143896 (2015)
Thrombocytopenia and increased platelet clearance observed in von Willebrand disease-type 2B (VWD-2B) may be explained by platelet apoptosis triggered by the constitutive binding of VWF to its receptor, glycoprotein Ib (GPIb). Apoptosis was assessed
Externí odkaz:
https://doaj.org/article/d8e2b4c2a0aa4289808c2ba24a245f90
Autor:
Idinath Badirou, Mohamad Kurdi, Paulette Legendre, Julie Rayes, Marijke Bryckaert, Caterina Casari, Peter J Lenting, Olivier D Christophe, Cecile V Denis
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37508 (2012)
The objective of this project was to study the function of O-glycosylations in von Willebrand factor (VWF) life cycle. In total, 14 different murine Vwf cDNAs mutated on one or several O-glycosylations sites were generated: 9 individual mutants, 2 do
Externí odkaz:
https://doaj.org/article/80df049f5c7640ac911c0da116a643b6
Autor:
Paulette Legendre, Melusine Didelot, Jeremy Lagrange, Olivier D. Christophe, Vincent Muczynski, Morel E Worou, Cécile V. Denis, Guillaume Gauchotte, Patrick Lacolley, François Plénat, Alexandre Raoul, Peter J. Lenting, Véronique Regnault, Jean-Baptiste Michel, Marc-Damien Lourenco-Rodrigues
Publikováno v:
Cardiovascular Research
Cardiovascular Research, Oxford University Press (OUP), 2021, ⟨10.1093/cvr/cvab042⟩
Cardiovascular Research, Oxford University Press (OUP), 2022, 118 (2), pp.622-637. ⟨10.1093/cvr/cvab042⟩
Cardiovascular Research, 2022, 118 (2), pp.622-637. ⟨10.1093/cvr/cvab042⟩
Cardiovascular Research, Oxford University Press (OUP), 2021, ⟨10.1093/cvr/cvab042⟩
Cardiovascular Research, Oxford University Press (OUP), 2022, 118 (2), pp.622-637. ⟨10.1093/cvr/cvab042⟩
Cardiovascular Research, 2022, 118 (2), pp.622-637. ⟨10.1093/cvr/cvab042⟩
Aims Von Willebrand factor (VWF) is a plasma glycoprotein involved in primary hemostasis, while also having additional roles beyond hemostasis namely in cancer, inflammation, angiogenesis and potentially in vascular smooth muscle cell (VSMC) prolifer
Autor:
Gaia Zirka, Paulette Legendre, Bart J.M. van Vlijmen, Philippe Robert, Victoria Tishkova, Chrissta X. Maracle, Peter J. Lenting, Grace M. Thomas, Julia Tilburg, Marie-Christine Alessi, Pierre-Emmanuel Morange
Publikováno v:
Blood
Blood, American Society of Hematology, 2021, 137 (16), pp.2256-2266. ⟨10.1182/blood.2020008345⟩
Blood, 137(16), 2256-2266. AMER SOC HEMATOLOGY
Blood, 2021, 137 (16), pp.2256-2266. ⟨10.1182/blood.2020008345⟩
Blood, American Society of Hematology, 2021, 137 (16), pp.2256-2266. ⟨10.1182/blood.2020008345⟩
Blood, 137(16), 2256-2266. AMER SOC HEMATOLOGY
Blood, 2021, 137 (16), pp.2256-2266. ⟨10.1182/blood.2020008345⟩
Genome-wide association studies linked expression of the human neutrophil antigen 3b (HNA-3b) epitope on the Slc44a2 protein with a 30% decreased risk of venous thrombosis (VT) in humans. Slc44a2 is a ubiquitous transmembrane protein identified as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f9af0f0e0962b657bcf10bc304fb0ee
https://hdl.handle.net/1887/3230185
https://hdl.handle.net/1887/3230185
Autor:
Mirko Pinotti, Cécile V. Denis, Matteo Campioni, Paulette Legendre, Peter J. Lenting, Caterina Casari, Cécile Loubière, Barbara Lunghi, Olivier D. Christophe, Francesco Bernardi
Publikováno v:
Journal of Thrombosis and Haemostasis
Journal of Thrombosis and Haemostasis, Wiley, 2020, Online ahead of print. ⟨10.1111/jth.15131⟩
Journal of Thrombosis and Haemostasis, Wiley, 2020, Online ahead of print. ⟨10.1111/jth.15131⟩
Essentials Treatment options for von Willebrand disease (VWD) patients are limited. The p.P1127_C1948delinsR deletion/variant is a useful model to study VWD in vitro and in vivo. Counteracting dominant-negative effects restores von Willebrand factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51bea8cbd9be7466d91b1cc62cec552f
https://www.hal.inserm.fr/inserm-02983110
https://www.hal.inserm.fr/inserm-02983110
Autor:
Vincent Muczynski, Valérie Proulle, Peter J. Lenting, François Moreau, Paulette Legendre, Charlotte Kawecki, Gabriel Aymé, Caterina Casari, Olivier D. Christophe, Cécile V. Denis
Publikováno v:
Blood
Blood, American Society of Hematology, 2018, 132 (11), pp.1193-1197. ⟨10.1182/blood-2018-01-829523⟩
Blood, American Society of Hematology, 2018, 132 (11), pp.1193-1197. ⟨10.1182/blood-2018-01-829523⟩
International audience; Von Willebrand factor (VWF) modulates factor VIII (FVIII) clearance and the anti-FVIII immune response. Despite the high affinity that defines the FVIII/VWF interaction, association/dissociation kinetics dictates 2% to 5% FVII
Autor:
Cécile V. Denis, Paulette Legendre, Peter J. Lenting, Frédéric Adam, Amine Bazaa, Olivier D. Christophe, Gabriel Aymé, Valérie Proulle
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology
Arteriosclerosis, Thrombosis, and Vascular Biology, American Heart Association, 2017, 37 (9), pp.1736-1740. ⟨10.1161/ATVBAHA.117.309319⟩
Arteriosclerosis, Thrombosis, and Vascular Biology, American Heart Association, 2017, 37 (9), pp.1736-1740. ⟨10.1161/ATVBAHA.117.309319⟩
Objective— von Willebrand factor (VWF) is crucial to hemostasis, but also plays a role in inflammatory processes. Unfortunately, no proper monoclonal antibodies to study VWF function in mice are currently available. We therefore aimed to generate s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46562edfbdd85d1915042d3ce0606975
http://hdl.handle.net/20.500.12278/39086
http://hdl.handle.net/20.500.12278/39086