Zobrazeno 1 - 10
of 389
pro vyhledávání: '"Paulette, Bioulac Sage"'
Autor:
Camille Dantzer, Justine Vaché, Aude Brunel, Isabelle Mahouche, Anne-Aurélie Raymond, Jean-William Dupuy, Melina Petrel, Paulette Bioulac-Sage, David Perrais, Nathalie Dugot-Senant, Mireille Verdier, Barbara Bessette, Clotilde Billottet, Violaine Moreau
Publikováno v:
eLife, Vol 13 (2024)
Immune checkpoint inhibitors have produced encouraging results in cancer patients. However, the majority of ß-catenin-mutated tumors have been described as lacking immune infiltrates and resistant to immunotherapy. The mechanisms by which oncogenic
Externí odkaz:
https://doaj.org/article/342f26d4191d4cf39318d96525b6cc9f
Autor:
Sara Basbous, Lydia Dif, Camille Dantzer, Sylvaine Di-Tommaso, Jean-William Dupuy, Paulette Bioulac-Sage, Anne-Aurélie Raymond, Chantal Desdouets, Frédéric Saltel, Violaine Moreau
Publikováno v:
Cell Death and Disease, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Entosis is a process that leads to the formation of cell-in-cell structures commonly found in cancers. Here, we identified entosis in hepatocellular carcinoma and the loss of Rnd3 (also known as RhoE) as an efficient inducer of this mechanis
Externí odkaz:
https://doaj.org/article/00a999658bed44e197ffd3d054843606
Autor:
Guillaume Declaux, Baudouin Denis de Senneville, Hervé Trillaud, Paulette Bioulac-Sage, Charles Balabaud, Jean-Frédéric Blanc, Laurent Facq, Nora Frulio
Publikováno v:
Research in Diagnostic and Interventional Imaging, Vol 10, Iss , Pp 100046- (2024)
Objectives: Non-invasive subtyping of hepatocellular adenomas (HCA) remains challenging for several subtypes, thus carrying different levels of risks and management. The goal of this study is to devise a multivariable diagnostic model based on basic
Externí odkaz:
https://doaj.org/article/2aa22bbc0a55433fb262bbc569dae134
Autor:
Sylvaine Di Tommaso, Cyril Dourthe, Jean-William Dupuy, Nathalie Dugot-Senant, David Cappellen, Hélène Cazier, Valérie Paradis, Jean-Frédéric Blanc, Brigitte Le Bail, Charles Balabaud, Paulette Bioulac-Sage, Frédéric Saltel, Anne-Aurélie Raymond
Publikováno v:
JHEP Reports, Vol 6, Iss 2, Pp 100913- (2024)
Background & Aims: Hepatocellular adenomas (HCAs) are rare, benign, liver tumours classified at the clinicopathological, genetic, and proteomic levels. The β-catenin-activated (b-HCA) subtypes harbour several mutation types in the β-catenin gene (C
Externí odkaz:
https://doaj.org/article/88ae01c559c44a39946de35c754a7779
Autor:
Caroline Gest, Sandra Sena, Lydia Dif, Véronique Neaud, Robin Loesch, Nathalie Dugot-Senant, Lisa Paysan, Léo Piquet, Terezinha Robbe, Nathalie Allain, Doulaye Dembele, Catherine Guettier, Paulette Bioulac-Sage, Anne Rullier, Brigitte Le Bail, Christophe F. Grosset, Frédéric Saltel, Valérie Lagrée, Sabine Colnot, Violaine Moreau
Publikováno v:
JHEP Reports, Vol 5, Iss 5, Pp 100691- (2023)
Background & Aims: β-catenin is a well-known effector of the Wnt pathway, and a key player in cadherin-mediated cell adhesion. Oncogenic mutations of β-catenin are very frequent in paediatric liver primary tumours. Those mutations are mostly hetero
Externí odkaz:
https://doaj.org/article/842490d9fd564a5d9087b3a228132176
Autor:
Margaux Sala, Delphine Gonzales, Thierry Leste‐Lasserre, Nathalie Dugot‐Senant, Valérie Paradis, Sylvaine Di Tommaso, Jean‐William Dupuy, Vincent Pitard, Cyril Dourthe, Amedeo Sciarra, Christine Sempoux, Linda D. Ferrell, Andrew D. Clouston, Gregory Miller, Mathew M. Yeh, Swan Thung, Annette S.H. Gouw, Alberto Quaglia, Jing Han, Ji Huan, Cathy Fan, James Crawford, Yasuni Nakanuma, Kenichi Harada, Brigitte leBail, Claire Castain, Nora Frulio, Hervé Trillaud, Laurent Possenti, Jean‐Frédéric Blanc, Laurence Chiche, Christophe Laurent, Charles Balabaud, Paulette Bioulac‐Sage, Anne Aurélie Raymond, Frédéric Saltel
Publikováno v:
Hepatology Communications, Vol 4, Iss 6, Pp 809-824 (2020)
Until recently, 10% of hepatocellular adenomas (HCAs) remained unclassified (UHCA). Among the UHCAs, the sonic hedgehog HCA (shHCA) was defined by focal deletions that fuse the promoter of Inhibin beta E chain with GLI1. Prostaglandin D2 synthase was
Externí odkaz:
https://doaj.org/article/a964102491fb4c51a8bbff73d7a74e81
Publikováno v:
JHEP Reports, Vol 4, Iss 3, Pp 100430- (2022)
Externí odkaz:
https://doaj.org/article/4eba804ec18344b5829fe915866716f4
Autor:
Quentin Bayard, Léa Meunier, Camille Peneau, Victor Renault, Jayendra Shinde, Jean-Charles Nault, Iadh Mami, Gabrielle Couchy, Giuliana Amaddeo, Emmanuel Tubacher, Delphine Bacq, Vincent Meyer, Tiziana La Bella, Audrey Debaillon-Vesque, Paulette Bioulac-Sage, Olivier Seror, Jean-Frédéric Blanc, Julien Calderaro, Jean-François Deleuze, Sandrine Imbeaud, Jessica Zucman-Rossi, Eric Letouzé
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Cyclins A2 and E1 are known to regulate the cell cycle by promoting S phase entry and progression. Here, they identify an aggressive hepatocellular carcinoma subgroup exhibiting cyclin activation through various mechanisms and find this subgroup to d
Externí odkaz:
https://doaj.org/article/d1c71c5d3832437783153fd87d02ea45
Autor:
Eric Letouzé, Jayendra Shinde, Victor Renault, Gabrielle Couchy, Jean-Frédéric Blanc, Emmanuel Tubacher, Quentin Bayard, Delphine Bacq, Vincent Meyer, Jérémy Semhoun, Paulette Bioulac-Sage, Sophie Prévôt, Daniel Azoulay, Valérie Paradis, Sandrine Imbeaud, Jean-François Deleuze, Jessica Zucman-Rossi
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Tumorigenesis is a complex process driven by numerous risk factors. Here, genomic analysis of liver cancer reveals the evolution of mutational signatures during tumor development, highlighting mutational and structural signatures linked to environmen
Externí odkaz:
https://doaj.org/article/a2db6282c9e94e1b953a8aca7a20d3f7
Autor:
Eric Chevet, Jean-Frédéric Blanc, Paulette Bioulac-Sage, Charles Balabaud, Jean Rosenbaum, Jeremy C. Simpson, Brigitte Le Bail, Claire Castain, Daniela Arma, Esther Marza, Mariana G. Bexiga, Said Taouji, Arisa Higa, Ping Yi
PDF file - 71K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ada58894ec2baa01b6ceca3b23ee702e
https://doi.org/10.1158/1535-7163.22496401.v1
https://doi.org/10.1158/1535-7163.22496401.v1
