Výsledky vyhledávání - "Paulene Sapao"

Reduced SPAG17 Expression in Systemic Sclerosis Triggers Myofibroblast Transition and Drives Fibrosis

Publikováno v: Journal of Investigative Dermatology. 143:284-293

Systemic sclerosis (SSc) is a clinically heterogeneous fibrotic disease with no effective treatment. Myofibroblasts are responsible for unresolving synchronous skin and internal organ fibrosis in SSc, but the drivers of sustained myofibroblast activa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db4eafd3194307cd3c0e58bfc4d56c4d
https://doi.org/10.1016/j.jid.2022.08.052

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Sperm Differentiation: The Role of Trafficking of Proteins

Autor: Maria E. Teves, Virali Bhagat, Paulene Sapao, Diego Krapf, Eduardo R. S. Roldan, Jerome F. Strauss

Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 3702, p 3702 (2020)
International Journal of Molecular Sciences
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Sperm differentiation encompasses a complex sequence of morphological changes that takes place in the seminiferous epithelium. In this process, haploid round spermatids undergo substantial structural and functional altera

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53375f612fb1da475586f840fa83d162
https://www.mdpi.com/1422-0067/21/10/3702

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The Primary Cilium: Emerging Role as a Key Player in Fibrosis

Autor: Jerome F. Strauss, Paulene Sapao, John Varga, Maria E. Teves, Bo Shi

Publikováno v: Current Rheumatology Reports. 21

The myofibroblast is the culprit in the pathogenesis of fibrosis in systemic sclerosis (SSc). Activation of morphogen signaling pathways has been shown to be critically involved in organ fibrosis. Remarkably, the cellular receptors and key molecules

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eb6154e0cc672bf59c124f4d6d23cc3
https://doi.org/10.1007/s11926-019-0822-0

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SPAG17 Is Required for Male Germ Cell Differentiation and Fertility

Autor: Paulene Sapao, Zhibing Zhang, HyunYoung Son, Elizabeth Kazarian, Jerome F. Strauss, Maria E. Teves, Wei Li

Publikováno v: International Journal of Molecular Sciences; Volume 19; Issue 4; Pages: 1252
International Journal of Molecular Sciences, Vol 19, Iss 4, p 1252 (2018)
International Journal of Molecular Sciences

Spag17 encodes a protein present in the axoneme central pair complex of motile cilia and flagella. A mutation in this gene has been reported to be associated with infertility caused by defects in sperm motility. Here, we report that Spag17 knockout m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c95149127b1adc2ebb58d50bed2e5430

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Genome Sequences of Chancellor, Mitti, and Wintermute, Three Subcluster K4 Phages Isolated Using Mycobacterium smegmatis mc 2 155

Autor: Kevin D. Zhang, Kourtney R. Mendello, Jamie B. Korenberg, Daniel A. Russell, John B. Balyozian, Nicholas P. Edgington, Gurvina J. Atwal, Graham F. Hatfull, Francis F. Akoto, Stephanie M. Voshell, Croldy A. Veliz, Netta Cudkevich, Brianna M. Chop, Catherine M. Mageeney, Bryan A. Pasqualucci, Inderjeet Singh, Dylan Z. Faltine-Gonzalez, Lauren N. McKinley, Rachel H. Swope, Lauren A. Vargas, Rebecca A. Garlena, Madeleine L. Walters, Alexander T. Nguyen, Brooke P. Lichak, Zachary A. Cadieux, Alexa A. Alhout, Vassie C. Ware, Welkin H. Pope, Julia R. Reisner, Cameron M. Myers, Lee H. Graham, Maryam A. Khan, Matthew S. Grapel, Ty H. Stoner, Deborah Jacobs-Sera, Caitlin M. Zuilkoski, Lauren M. Pyfer, Maaz M. Haleem, Margaret A. Kenna, Wascar A. Ramirez, Blair J. Gilmer, Steven G. Cresawn, Taylor N. Klein, Matthew J. Thoonkuzhy, Paulene Sapao, Virginia C. Saux

Publikováno v: Genome Announcements. 5

Mycobacteriophages Chancellor, Mitti, and Wintermute infect Mycobacterium smegmatis mc 2 155 and are closely related to phages Cheetobro and Fionnbharth in subcluster K4. Genome sizes range from 57,697 bp to 58,046 bp. Phages are predicted to be temp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::34bb06351af7876dec6832c5d53d1b83
https://doi.org/10.1128/genomea.01070-17

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955 Altered expression of SPAG17, a cilia-related gene, in scleroderma and spontaneous skin fibrosis in Spag17 knockout mice suggests that scleroderma is a unique ciliopathy

Autor: Paulene Sapao, John P. Atkinson, Jerome F. Strauss, Maria E. Teves, Elisha D.O. Roberson, John Varga, Bo Shi

Publikováno v: Journal of Investigative Dermatology. 139:S165

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b1ee42d6cef78efa9276ecb81226d350
https://doi.org/10.1016/j.jid.2019.03.1031

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