Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Paula Zen Petisco Fiore A"'
Autor:
Ana Paula Zen Petisco Fiore, Shuvadeep Maity, Lauren Jeffery, Disi An, Justin Rendleman, Dylan Iannitelli, Hyungwon Choi, Esteban Mazzoni, Christine Vogel
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113885- (2024)
Summary: Amyotrophic lateral sclerosis damages proteostasis, affecting spinal and upper motor neurons earlier than a subset of cranial motor neurons. To aid disease understanding, we exposed induced cranial and spinal motor neurons (iCrMNs and iSpMNs
Externí odkaz:
https://doaj.org/article/ec67cb62c095414cb313530ab059cdee
Publikováno v:
Bio-Protocol, Vol 13, Iss 18 (2023)
Eukaryotic cells have different types of proteasomes that differ in size. The smallest proteolytically active particle is the 20S proteasome, which degrades damaged and oxidized proteins; the most common larger particle is the 26S proteasome, which d
Externí odkaz:
https://doaj.org/article/d2fd885dc55f4f5b8bc4bf00731d86ad
Akademický článek
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Autor:
Rodrigues, Ana Maria, Paula Zen Petisco Fiore, Ana, Guardia, Gabriela D. A., Tomasin, Rebeka, Azevedo Reis Teixeira, André, Giordano, Ricardo Jose, Schechtman, Deborah, Pagano, Michele, Galante, Pedro A. F., Bruni-Cardoso, Alexandre
Publikováno v:
Oncogene; September 2024, Vol. 43 Issue: 39 p2938-2950, 13p
Autor:
Otto Luiz Dutra Cerqueira, Mayara Carolline Silva Botelho, Ana Paula Zen Petisco Fiore, Cynthia Aparecida Bueno de Toledo Osório, Rebeka Tomasin, Mauro César Cafundó Morais, Rossana Verónica Mendoza López, Elaine Cristina Cardoso, Santiago Andres Vilella-Arias, Eduardo Moraes Reis, Alexandre Bruni-Cardoso
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 30, Iss , Pp 100803- (2022)
Invasion of surrounding stroma is an early event in breast cancer metastatic progression, and involves loss of cell polarity, loss of myoepithelial layer, epithelial-mesenchymal transition (EMT) and remodeling of the extracellular matrix (ECM). Integ
Externí odkaz:
https://doaj.org/article/9bcfb0687f1f46b6a63f32c737d0a562
Autor:
Ana Paula Zen Petisco Fiore, Virginia A. Spencer, Hidetoshi Mori, Hernandes F. Carvalho, Mina J. Bissell, Alexandre Bruni-Cardoso
Publikováno v:
Cell Reports, Vol 19, Iss 10, Pp 2102-2115 (2017)
Nuclear actin (N-actin) is known to participate in the regulation of gene expression. We showed previously that N-actin levels mediate the growth and quiescence of mouse epithelial cells in response to laminin-111 (LN1), a component of the mammary ba
Externí odkaz:
https://doaj.org/article/6e67de02ed454b62a9814af031d58cf1
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 6 (2018)
Cells from prokaryota to the more complex metazoans cease proliferating at some point in their lives and enter a reversible, proliferative-dormant state termed quiescence. The appearance of quiescence in the course of evolution was essential to the a
Externí odkaz:
https://doaj.org/article/a3e853140ae1452c8cac28d8698b18e2
Autor:
Ana Paula Zen Petisco Fiore, Shuvadeep Maity, Disi An, Justin Rendleman, Dylan Iannitelli, Hyungwon Choi, Esteban Mazzoni, Christine Vogel
Amyotrophic Lateral Sclerosis (ALS) is a fatal adult neurodegenerative disease characterized by proteostasis dysregulation, resulting in progressive loss of spinal and upper motor neurons. A subset of cranial motor neurons resistant to ALS-stress sur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50f393a58562ae853e44da6d44296fa5
https://doi.org/10.1101/2022.04.10.487765
https://doi.org/10.1101/2022.04.10.487765
Autor:
Ana Paula Zen Petisco Fiore, Ana Maria Rodrigues, Helder Veras Ribeiro-Filho, Antonio Carlos Manucci, Pedro de Freitas Ribeiro, Mayara Carolinne Silva Botelho, Christine Vogel, Paulo Sergio Lopes-de-Oliveira, Michele Pagano, Alexandre Bruni-Cardoso
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
The Hippo pathway plays central roles in relaying mechanical signals during development and tumorigenesis, but how the proteostasis of the Hippo kinase MST2 is regulated remains unknown. Here, we found that chemical inhibition of proteasomal proteoly
Autor:
Görkem Garipler, Congyi Lu, Alexis Morrissey, Lorena S. Lopez-Zepeda, Yingzhen Pei, Simon E. Vidal, Ana Paula Zen Petisco Fiore, Begüm Aydin, Matthias Stadtfeld, Uwe Ohler, Shaun Mahony, Neville E. Sanjana, Esteban O. Mazzoni
Publikováno v:
Cell Reports. 38:110524
In pluripotent cells, a delicate activation-repression balance maintains pro-differentiation genes ready for rapid activation. The identity of transcription factors (TFs) that specifically repress pro-differentiation genes remains obscure. By targeti