Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Paula Woodbridge"'
Publikováno v:
Internal Medicine Journal. 43:150-156
Background/Aim The nuclear POLG gene encodes the catalytic subunit of DNA polymerase gamma (polγ), the only polymerase involved in the replication and proofreading of mitochondrial DNA. As a consequence, POLG mutations can cause disease through impa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f1a6edb4c55c2fc6f0ccfae64d810f3
https://doi.org/10.1111/j.1445-5994.2012.02847.x
https://doi.org/10.1111/j.1445-5994.2012.02847.x
Autor:
Paula Woodbridge, Vanessa M. Hayes, Katharina Schipany, Desiree C. Petersen, Elizabeth A. Tindall
Publikováno v:
Human Mutation. 30:876-883
Mutation detection has, until recently, relied heavily on the use of gel-based methods that can be both time consuming and difficult to design. Nongel-based systems are therefore important to increase simplicity and improve turn around time without c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4037db03953a8a87b955e57152c180d
https://doi.org/10.1002/humu.20919
https://doi.org/10.1002/humu.20919
Autor:
Stephan C. Schuster, Qingyu Wang, Gregory M. Woods, Desiree C. Petersen, James W. Knight, Jason R. Miller, Oscar C. Bedoya-Reina, Arthur M. Lesk, Stephen Pyecroft, Neerja Katiyar, Yu Zhang, Menna E. Jones, Fangqing Zhao, Nicola E. Wittekindt, Paula Woodbridge, Elizabeth A. Tindall, Lynn P. Tomsho, Dale Dixon, Ji Qi, Rae-Anne Hardie, Mads F. Bertelsen, Vanessa M. Hayes, Brian P. Walenz, Kristofer M. Helgen, Thomas H. Pringle, Lindsay Mc Clellan Kasson, Webb Miller, Nick Patterson, Aakrosh Ratan, Alexandre Kreiss
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 108(30)
The Tasmanian devil ( Sarcophilus harrisii ) is threatened with extinction because of a contagious cancer known as Devil Facial Tumor Disease. The inability to mount an immune response and to reject these tumors might be caused by a lack of genetic d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::370b2e6e028abfa788c81c6a98b8d8eb
https://pubmed.ncbi.nlm.nih.gov/21709235
https://pubmed.ncbi.nlm.nih.gov/21709235
Publikováno v:
Journal of Clinical Neuroscience. 21:2049-2050
POLG is a gene that encodes the catalytic subunit of DNA polymerase gamma (polγ). Polγ is responsible for mtDNA replication, and aberrant replication can lead to mitochondrial dysfunction and decreased adenosine triphosphate (ATP) production. Neuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e42e2ebd28d7d9e100d8806bf82986d5
https://doi.org/10.1016/j.jocn.2014.06.066
https://doi.org/10.1016/j.jocn.2014.06.066
Autor:
Christopher W. Vaughan, Ernst J. Wolvetang, Carolyn M. Sue, Nicholas F. Blair, Paula Woodbridge, Stephen Gao
Publikováno v:
Journal of Clinical Neuroscience. 21:2056
Parkinson’s disease (PD) is a common neurodegenerative disorder with no current treatment that arrests the progress of the disease. The objective of this study was to develop cellular models of PD for use in the study of the pathophysiological path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08905610c8ff6cb8453d7c1f6b6d6180
https://doi.org/10.1016/j.jocn.2014.06.088
https://doi.org/10.1016/j.jocn.2014.06.088
Autor:
Stephan C. Schuster, Menna E. Jones, Paula Woodbridge, Qingyu Wang, Kristofer M. Helgen, Jason R. Miller, Elizabeth A. Tindall, Desiree C. Petersen, James W. Knight, Oscar C. Bedoya-Reina, Alexandre Kreiss, Stephen Pyecroft, Arthur M. Lesk, Neerja Katiyar, Lynn P. Tomsho, Vanessa M. Hayes, Dale Dixon, Nick Patterson, Thomas H. Pringle, Aakrosh Ratan, Gregory M. Woods, Rae-Anne Hardie, Fangqing Zhao, Mads F. Bertelsen, Ji Qi, Yu Zhang, Lindsay Mc Clellan Kasson, Webb Miller, Nicola E. Wittekindt, Brian P. Walenz
Publikováno v:
Proceedings of the National Academy of Sciences. 109:18625-18625
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a29d44721cb9393e7ac402b26bddcbd5
https://doi.org/10.1073/pnas.1217345109
https://doi.org/10.1073/pnas.1217345109