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pro vyhledávání: '"Paula V. Mayshar"'
Publikováno v:
Cardiovascular Drugs and Therapy. 4:493-497
In 82 healthy normotensive and hypertensive subjects aged 19-79, blood pressure and heart rate were measured for 1 hour before and 2 hours after a meal. Mean blood pressure decreased from 147/93 to 139/83 mmHg supine and from 148/101 to 142/94 mmHg s
Autor:
Mary J. Mackie, F. C. Falkner, Paula V. Mayshar, J. D. Lazar, Timothy C. Fagan, Kenneth A. Conrad, J. F. Souhrada, Stanley M. Lee
Publikováno v:
European Journal of Clinical Pharmacology. 35:21-24
The antihypertensive effects and steady-state pharmacokinetics of doxazosin, as well as the bioequivalence of four dosage forms, were studied in 25 hypertensive patients. For an 8 mg daily dose mean Cmax at steady-state for all patients was 108 ng/ml
Publikováno v:
Clinical Pharmacology and Therapeutics. 42:113-118
We studied the safety and efficacy of intravenous nicardipine alone and in combination with oral captopril. Sixteen patients with essential hypertension received a single oral dose of captopril, 50 mg, to be certain that excessive hypotension would n
Publikováno v:
Clinical Pharmacology and Therapeutics. 43:542-546
Ketorolac tromethamine, an analgesic agent with prostaglandin synthetase–inhibiting activity, is more active than aspirin in vitro in inhibiting collagen– or arachidonic acid–induced platelet aggregation. In this randomized, double-blind study,
Publikováno v:
Hypertension. 11:282-284
The mean of rapidly repeated duplicate or triplicate measurements is often used in studies of antihypertensive drugs. Forty patients with hypertension had triplicate measurements of blood pressure and heart rate on two occasions, 1 week apart, during