Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Paula V. Bennett"'
Autor:
Alicia M. Johnson, Paula V. Bennett, Katherine Z. Sanidad, Anthony Hoang, James H. Jardine, Deborah J. Keszenman, Paul F. Wilson
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Significant opportunities remain for pharmacologically enhancing the clinical effectiveness of proton and carbon ion-based radiotherapies to achieve both tumor cell radiosensitization and normal tissue radioprotection. We investigated whether pretrea
Externí odkaz:
https://doaj.org/article/223c984ca18d4294acd276e3bc607b57
Autor:
Deborah J. Keszenman, Alicia M. Johnson, Katherine Z. Sanidad, James Jardine, Anthony Hoang, Paul F. Wilson, Paula V. Bennett
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, Vol 11 (2021)
Frontiers in Oncology, Vol 11 (2021)
Significant opportunities remain for pharmacologically enhancing the clinical effectiveness of proton and carbon ion-based radiotherapies to achieve both tumor cell radiosensitization and normal tissue radioprotection. We investigated whether pretrea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aa09d6c603faadd64553578bab27541
http://europepmc.org/articles/PMC8426582
http://europepmc.org/articles/PMC8426582
Autor:
Paula V. Bennett, Alicia M. Johnson, Sarah E. Ackerman, Pankaj Chaudhary, Deborah J. Keszenman, Paul F. Wilson
Publikováno v:
Radiation research. 197(3)
We report on effects of low-dose exposures of accelerated protons delivered at high-dose rate (HDR) or a simulated solar-particle event (SPE) like low-dose rate (LDR) on immediate DNA damage induction and processing, survival and in vitro transformat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c823b98ba2bd944193bb2bdb2753c5e
https://pubmed.ncbi.nlm.nih.gov/34910217
https://pubmed.ncbi.nlm.nih.gov/34910217
Publikováno v:
Radiation Research. 176:217-225
Solar particle events (SPEs) present a major radiation-related risk for manned exploratory missions in deep space. Within a short period the astronauts may absorb doses that engender acute effects, in addition to the risk of late effects, such as the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d460948f4c12ed41fc40c07c9828d66
https://doi.org/10.1667/rr2490.1
https://doi.org/10.1667/rr2490.1
Publikováno v:
Radiation and Environmental Biophysics. 46:119-123
Since radiation fields of space contain many-fold more protons than high atomic number, high energy (HZE) particles, cells in astronaut crews will experience on average several proton hits before an HZE hit. Thus radiation regimes of proton exposure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4daf2bcb94759d2ae50d7ddf8c63345
https://doi.org/10.1007/s00411-006-0091-y
https://doi.org/10.1007/s00411-006-0091-y
Publikováno v:
Radiation Research. 166:488-494
The radiation field in deep space contains high levels of high-energy protons and substantially lower levels of high-atomic-number, high-energy (HZE) particles. Calculations indicate that cellular nuclei of human space travelers will be hit during a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::943f40f28c5971561c63f2e25c2293d5
https://doi.org/10.1667/rr0596.1
https://doi.org/10.1667/rr0596.1
Publikováno v:
Radiation Research. 164:493-496
Travelers on space missions will be exposed to a complex radiation environment that includes protons and heavy charged particles. Since protons are present at much higher levels than are heavy ions, the most likely scenario for cellular radiation exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1b65a3ccd9b10d642ca0868a22b181f
https://doi.org/10.1667/rr3357.1
https://doi.org/10.1667/rr3357.1
Publikováno v:
Nucleic Acids Research. 32:5609-5620
Clustered DNA damages--two or more lesions on opposing strands and within one or two helical turns--are formed in cells by ionizing radiation or radiomimetic antitumor drugs. They are hypothesized to be difficult to repair, and thus are critical biol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8502adecb5333288373b41e921a58a6
https://doi.org/10.1093/nar/gkh871
https://doi.org/10.1093/nar/gkh871
Autor:
Kays Kaidbey, Wayne G. Wamer, Andrija Kornhauser, Paula V. Bennett, Donna A. Dennis, Betsy M. Sutherland, Curtis N. Barton
Publikováno v:
Photodermatology, Photoimmunology & Photomedicine. 19:21-27
Background: Alpha-hydroxy acids (AHAs) are widely used as ingredients in cosmetics. Several studies suggest that AHAs can increase the sensitivity of skin to ultraviolet (UV) light. Purpose: This study was performed in order to determine whether shor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97fdc47a318aef1ce378c28a07516389
https://doi.org/10.1034/j.1600-0781.2003.00013.x
https://doi.org/10.1034/j.1600-0781.2003.00013.x
Publikováno v:
Nucleic Acids Research. 30:2800-2808
Bi-stranded abasic clusters, an abasic (AP) site on one DNA strand and another nearby AP site or strand break on the other, have been quantified using Nfo protein from Escherichia coli to produce a double-strand break at cluster sites. Since recent d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::979db698fbe565d07857f81689577b31
https://doi.org/10.1093/nar/gkf393
https://doi.org/10.1093/nar/gkf393