Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Paula Tomas Ojer"'
Autor:
Paula Tomas-Ojer, Marco Puthenparampil, Carolina Cruciani, María José Docampo, Roland Martin, Mireia Sospedra
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
Antigen-induced T-cell exhaustion and T-cell senescence are peripheral regulatory mechanisms that control effector T-cell responses. Markers of exhaustion and senescence on T Cells indicate the previous activation by repetitive stimulation with speci
Externí odkaz:
https://doaj.org/article/d1f320c95c3a496dbfe1c4ea0cbbe333
Autor:
Wolfgang Faigle, Carolina Cruciani, Witold Wolski, Bernd Roschitzki, Marco Puthenparampil, Paula Tomas-Ojer, Carla Sellés-Moreno, Thomas Zeis, Ivan Jelcic, Nicole Schaeren-Wiemers, Mireia Sospedra, Roland Martin
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Immune responses to citrullinated peptides have been described in autoimmune diseases like rheumatoid arthritis (RA) and multiple sclerosis (MS). We investigated the post-translational modification (PTM), arginine to citrulline, in brain tissue of MS
Externí odkaz:
https://doaj.org/article/86cec64a578c4a76a068f569debcf85b
Autor:
Roland Martin, Patrick Roth, Michael Weller, Luca Regli, Bernd Bodenmiller, Erich F. Greiner, Holger Moch, Mireia Sospedra, Andreas Lutterotti, Catherine J. Wu, Ron McKay, Joo Heon Shin, Barbara Schrörs, Susanne Dettwiler, Elisabeth Rushing, Daniel Schulz, Ivan Jelcic, Gioele Medici, Paula Tomas Ojer, Magdalena Foege, Carla Sellés Moreno, Reza Naghavian, Nora C. Toussaint, Marian C. Neidert, Tobias Weiss, Jian Wang
Designed mutations increase the stimulatory strength of D-neopeptides above N-peptides. (A) TILs were stimulated with 5 μM class I-peptides, including N-peptides and D-neopeptides, for 5 days. 5 replicate wells were tested for proliferation, and pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ceb25277d9242b2898736907629a9d6
https://doi.org/10.1158/1078-0432.22488566
https://doi.org/10.1158/1078-0432.22488566
Autor:
Roland Martin, Patrick Roth, Michael Weller, Luca Regli, Bernd Bodenmiller, Erich F. Greiner, Holger Moch, Mireia Sospedra, Andreas Lutterotti, Catherine J. Wu, Ron McKay, Joo Heon Shin, Barbara Schrörs, Susanne Dettwiler, Elisabeth Rushing, Daniel Schulz, Ivan Jelcic, Gioele Medici, Paula Tomas Ojer, Magdalena Foege, Carla Sellés Moreno, Reza Naghavian, Nora C. Toussaint, Marian C. Neidert, Tobias Weiss, Jian Wang
Predicted TSA/TAA-derived N-peptides and D-neopeptides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::076b20fe5359c6604ca16659aeb889ad
https://doi.org/10.1158/1078-0432.22488554.v1
https://doi.org/10.1158/1078-0432.22488554.v1
Autor:
Roland Martin, Patrick Roth, Michael Weller, Luca Regli, Bernd Bodenmiller, Erich F. Greiner, Holger Moch, Mireia Sospedra, Andreas Lutterotti, Catherine J. Wu, Ron McKay, Joo Heon Shin, Barbara Schrörs, Susanne Dettwiler, Elisabeth Rushing, Daniel Schulz, Ivan Jelcic, Gioele Medici, Paula Tomas Ojer, Magdalena Foege, Carla Sellés Moreno, Reza Naghavian, Nora C. Toussaint, Marian C. Neidert, Tobias Weiss, Jian Wang
Purpose:The low mutational load of some cancers is considered one reason for the difficulty to develop effective tumor vaccines. To overcome this problem, we developed a strategy to design neopeptides through single amino acid mutations to enhance th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::194ce836ba5d5bdee824d491fbddf768
https://doi.org/10.1158/1078-0432.c.6532760
https://doi.org/10.1158/1078-0432.c.6532760
Autor:
Roland Martin, Patrick Roth, Michael Weller, Luca Regli, Bernd Bodenmiller, Erich F. Greiner, Holger Moch, Mireia Sospedra, Andreas Lutterotti, Catherine J. Wu, Ron McKay, Joo Heon Shin, Barbara Schrörs, Susanne Dettwiler, Elisabeth Rushing, Daniel Schulz, Ivan Jelcic, Gioele Medici, Paula Tomas Ojer, Magdalena Foege, Carla Sellés Moreno, Reza Naghavian, Nora C. Toussaint, Marian C. Neidert, Tobias Weiss, Jian Wang
Supplementary Table 1. Somatic mutations of the patient's glioblastoma; Supplementary Table 2. See Excel File; Supplementary Table 3. Literature-derived, glioblastoma-associated TAAs; Supplementary Table 4. See Excel File; Supplementary Table 5. Over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5715d4604cc355dbcad734a421599798
https://doi.org/10.1158/1078-0432.22488560.v1
https://doi.org/10.1158/1078-0432.22488560.v1
Autor:
Jian Wang, Tobias Weiss, Marian C. Neidert, Nora C. Toussaint, Reza Naghavian, Carla Sellés Moreno, Magdalena Foege, Paula Tomas Ojer, Gioele Medici, Ivan Jelcic, Daniel Schulz, Elisabeth Rushing, Susanne Dettwiler, Barbara Schrörs, Joo Heon Shin, Ron McKay, Catherine J. Wu, Andreas Lutterotti, Mireia Sospedra, Holger Moch, Erich F. Greiner, Bernd Bodenmiller, Luca Regli, Michael Weller, Patrick Roth, Roland Martin
Publikováno v:
Clinical Cancer Research, 28 (24)
Purpose: The low mutational load of some cancers is considered one reason for the difficulty to develop effective tumor vaccines. To overcome this problem, we developed a strategy to design neopeptides through single amino acid mutations to enhance t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d8dbb57d4e9eeaff591ab97ad18c938
https://www.zora.uzh.ch/id/eprint/221622/
https://www.zora.uzh.ch/id/eprint/221622/
Autor:
Paula, Tomas-Ojer, Puthenparampil, Marco, Thorsten, Hornemann, Andreas, Lutterotti, Ilijas, Jelcic, Mario, Ziegler, Andreas, J Hülsmeier, Carolina, Cruciani, Wolfgang, Faigle, Roland, Martin, Mireia, Sospedra.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3657::00726277b0e091b2448d17a269ef252d
https://hdl.handle.net/11577/3466774
https://hdl.handle.net/11577/3466774
Autor:
Paula, Tomas-Ojer, Marco, Puthenparampil, Carolina, Cruciani, María José, Docampo, Roland, Martin, Mireia, Sospedra
Publikováno v:
Frontiers in neurology. 13
Antigen-induced T-cell exhaustion and T-cell senescence are peripheral regulatory mechanisms that control effector T-cell responses. Markers of exhaustion and senescence on T Cells indicate the previous activation by repetitive stimulation with speci
Autor:
Marco Puthenparampil, Mireia Sospedra, Ilijas Jelcic, Andreas Lutterotti, Carolina Cruciani, Wolfgang Faigle, Andreas J. Hülsmeier, Mario Ziegler, Thorsten Hornemann, Paula Tomas-Ojer, Roland Martin
Publikováno v:
Neurology® Neuroimmunology & Neuroinflammation
article-version (Version of Record) 3
article-version (Version of Record) 3
ObjectiveCNS damage can increase the susceptibility of the blood-brain barrier (BBB) to changes induced by systemic inflammation. The aim of this study is to better understand BBB permeability in patients with MS and to examine whether compromised BB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c2b65737a33693b9a4d77d96839178d
https://doi.org/10.5167/uzh-205256
https://doi.org/10.5167/uzh-205256