Výsledky vyhledávání - "Paula Stonemetz"

Development and Clinical Utility of a Blood-Based Test Service for the Rapid Identification of Actionable Mutations in Non–Small Cell Lung Carcinoma

Autor: Ubaradka G. Sathyanarayana, Kristina Koch, Hestia Mellert, Samantha Cooper, Trudi Foreman, Paula Stonemetz, Scott Thurston, Westen Hahn, Jakkie Greer, Dawne N. Shelton, Dianna Maar, Leisa Jackson, Nicholas F. Dupuis, Gary Pestano, Amanda Weaver

Publikováno v: The Journal of Molecular Diagnostics. 19:404-416

Nearly 80% of cancer patients do not have genetic mutation results available at initial oncology consultation; up to 25% of patients begin treatment before receiving their results. These factors hinder the ability to pursue optimal treatment strategi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9a9996e3d72a3208e4fdea996bcf052
https://doi.org/10.1016/j.jmoldx.2016.11.004

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Abstract 2847: Quantitative assessment of circulating BRAF DNA in stage IV melanoma patients undergoing BRAF inhibitor treatment

Autor: Yongzhao Shao, Cindy Spittle, David Polsky, Jyothi Sakuntala Tadepalli, Anna C. Pavlick, Dawne N. Shelton, Gregory Chang, Iman Osman, Paula Stonemetz, Manohar R. Furtado, Nathaniel H. Fleming, George Karlin-Neumann

Publikováno v: Cancer Research. 74:2847-2847

Introduction: Our group has been developing methods to quantitatively detect mutant BRAF DNA in the plasma of metastatic melanoma patients, with the aim of developing new biomarker assays. In this study we evaluated the potential of a probe-based, dr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::30a2b62792077dd7e4496bb6cb23bb8b
https://doi.org/10.1158/1538-7445.am2014-2847

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Droplet digital PCR monitoring of BRAF and NRAS plasma DNA as biomarkers of treatment response in stage IV melanoma

Autor: George Karlin-Neumann, Jyothirmayee S. Tadepalli, Manohar R. Furtado, Nathaniel H. Fleming, David Polsky, Anna C. Pavlick, Yongzhao Shao, Dawne N. Shelton, Iman Osman, Paula Stonemetz, Gregory Chang, Cynthia Spittle

Publikováno v: Journal of Clinical Oncology. 32:9019-9019

9019 Background: Management of melanoma suffers from a lack of robust biomarkers of disease activity. In this study, we tested the ability of droplet digital PCR (ddPCR) to quantitatively measure levels of circulating BRAF and NRAS mutant DNA in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::39b98470b879963e6af38e1c5e43e9b6
https://doi.org/10.1200/jco.2014.32.15_suppl.9019

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