Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Paula Stanley"'
Publikováno v:
Biology Open, Vol 1, Iss 11, Pp 1161-1168 (2012)
Summary T lymphocytes make use of their major integrin LFA-1 to migrate on surfaces that express ICAM-1 such as blood vessels and inflamed tissue sites. How the adhesions are turned over in order to supply traction for this migration has not been ext
Externí odkaz:
https://doaj.org/article/cd51b3013fde41be900b971e897e0794
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38517 (2012)
The role of Gαi proteins coupled to chemokine receptors in directed migration of immune cells is well understood. In this study we show that the separate class of Gαq/11 proteins is required for the underlying ability of T cells to migrate both ran
Externí odkaz:
https://doaj.org/article/1d4ad37161ce4e5cbc5f3b19222123c5
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e15090 (2010)
The immune cells named T lymphocytes circulate around the body fulfilling their role in immunosurveillance by monitoring the tissues for injury or infection. To migrate from the blood into the tissues, they make use of the integrin LFA-1 which is exc
Externí odkaz:
https://doaj.org/article/deec9431f01c4559951c5b4887c75290
Autor:
Pamela Kachmar, Qing Sun, Brittany Boehm, Tara Hartle, Amanda Brown, Mylarappa Ningappa, George V. Mazariegos, Sarangarajan Ranganathan, Chethan Ashokkumar, Patricia Harris, Adriana Zeevi, Ronald Jaffe, Lisa Remaley, Paula Stanley, Geoffrey Bond, Samantha Levy, Nicole Jativa, Megan Nicely, Brandon W. Higgs, Jaimie White, Kyle Soltys, Katie Dirling, Rakesh Sindhi, Lindsay OʼToole, Tamara Fazzolare
Publikováno v:
Transplantation. 101:131-140
Background Allospecific CD154+T-cytotoxic memory cells (CD154+TcM) predict acute cellular rejection after liver transplantation (LTx) or intestine transplantation (ITx) in small cohorts of children and can enhance immunosuppression management, but aw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76bf210fceaaf46fab8ffe565cbde0af
https://doi.org/10.1097/tp.0000000000001076
https://doi.org/10.1097/tp.0000000000001076
Publikováno v:
Biology Open, Vol 1, Iss 11, Pp 1161-1168 (2012)
Biology Open
Biology Open
Summary T lymphocytes make use of their major integrin LFA-1 to migrate on surfaces that express ICAM-1 such as blood vessels and inflamed tissue sites. How the adhesions are turned over in order to supply traction for this migration has not been ext
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea07a00d7488787267ddf226c60d5fe
http://bio.biologists.org/content/1/11/1161
http://bio.biologists.org/content/1/11/1161
Intermediate-affinity LFA-1 binds α-actinin-1 to control migration at the leading edge of the T cell
Publikováno v:
The EMBO Journal
T lymphocytes use LFA-1 to migrate into lymph nodes and inflammatory sites. To investigate the mechanisms regulating this migration, we utilize mAbs selective for conformational epitopes as probes for active LFA-1. Expression of the KIM127 epitope, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7344c8bb8b6e691385133e5db349cba7
http://europepmc.org/articles/PMC2147999
http://europepmc.org/articles/PMC2147999
Publikováno v:
Immunological Reviews. 218:135-146
A successful immune response depends on the migration of lymphocytes into lymph nodes or inflamed tissues where they make contact with antigen-presenting cells. We are interested in how one member of the integrin family, leukocyte function-associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5321561eadf3a1ed633a4c6bec1498f0
https://doi.org/10.1111/j.1600-065x.2007.00537.x
https://doi.org/10.1111/j.1600-065x.2007.00537.x
Autor:
Facundo D. Batista, Andrew M. Smith, Yolanda R. Carrasco, Nancy Hogg, Paula Stanley, Nelly Kieffer
Publikováno v:
The Journal of Cell Biology
Cells such as fibroblasts and endothelial cells migrate through the coordinated responses of discrete integrin-containing focal adhesions and complexes. In contrast, little is known about the organization of integrins on the highly motile T lymphocyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fb9fee2d469fd679ab02d14a76f75d9
https://doi.org/10.1083/jcb.200412032
https://doi.org/10.1083/jcb.200412032
Autor:
Katherine Giles, Melanie Laschinger, Nancy Hogg, Paula Stanley, Robert B. Henderson, Alison McDowall, Andrew M. Smith
Publikováno v:
Immunology Letters. 92:51-54
The T lymphocyte (or T cell) has classically been perceived to be a passive circular cell attaching to other cells or fibrils of the extracellular matrix when its integrins become activated. We now understand that the modus operandi of the T cell is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a80e9fba1d38e86838a52ffa2488c3eb
https://doi.org/10.1016/j.imlet.2003.10.014
https://doi.org/10.1016/j.imlet.2003.10.014
Autor:
Nancy Hogg, Joanna C. Porter, Paula Stanley, Robert A. Henderson, Alison McDowall, Birgit Leitinger
Publikováno v:
Immunological Reviews. 186:164-171
Understanding how the integrins on leukocytes operate is important because these receptors control the activity of leukocytes in all phases of their lives. Thus integrins control leukocyte development and maturation in bone marrow, the circulation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9675b1523b8282e5cd1cb6f79a6517ef
https://doi.org/10.1034/j.1600-065x.2002.18614.x
https://doi.org/10.1034/j.1600-065x.2002.18614.x