Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Paula Sjödin"'
Autor:
Hugo Gutiérrez-de-Terán, Helena Åkerberg, Dan Larhammar, Ingrid Lundell, Helena Fällmar, Lars Boukharta, Paula Sjödin, Nina Mohell
Publikováno v:
Regulatory Peptides. 163:120-129
Neuropeptide Y (NPY) and peptide YY (PYY) share approximately 70% of their 36 amino acids and bind to the same three human receptor subtypes, Y1, Y2 and Y5, even though these receptors only share approximately 30% sequence identity. Based on our prev
Publikováno v:
Regulatory Peptides. 133:32-40
The NPY receptors belong to the superfamily of G-protein coupled receptors and in mammals this family has five members, named Y1, Y2, Y4, Y5, and Y6. In bony fish, four receptors have been identified, named Ya, Yb, Yc and Y7. Yb and Y7 arose prior to
Autor:
Dan Larhammar, Nina Mohell, Rima Zoorob, Torun Bromée, Robert Fredriksson, Tomas A. Larsson, Erik Salaneck, Paula Sjödin, Timothy Boswell
Publikováno v:
The FEBS journal. 273(9)
The peptides of the neuropeptide Y (NPY) family exert their functions, including regulation of appetite and circadian rhythm, by binding to G-protein coupled receptors. Mammals have five subtypes, named Y1, Y2, Y4, Y5 and Y6, and recently Y7 has been
Publikováno v:
Biochemical Journal. 398:613-613
Interactions of the human NPY (neuropeptide Y) receptor Y1 with the two endogenous agonists NPY and peptide YY and two non-peptide antagonists were investigated using site-directed mutagenesis at 17 positions. The present study was triggered by contr