Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Paula Santos-Otte"'
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-7 (2020)
Membrane proteins are embedded in the lipid bilayer of the plasma membrane and their function in this context is often linked to their specific location and dynamics within the membrane. Here authors report the use of fluorescent magnetic nanoparticl
Externí odkaz:
https://doaj.org/article/3a658df9ef4843eda3115f093781a422
Autor:
Paula Santos-Otte, Hanne Leysen, Jaana van Gastel, Jhana O. Hendrickx, Bronwen Martin, Stuart Maudsley
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 17, Iss , Pp 1265-1277 (2019)
Aging is a complex biological process that is inevitable for nearly all organisms. Aging is the strongest risk factor for development of multiple neurodegenerative disorders, cancer and cardiovascular disorders. Age-related disease conditions are mai
Externí odkaz:
https://doaj.org/article/b817be3f565c41b19aa597b80d1164c2
Autor:
Jhana O. Hendrickx, Jaana van Gastel, Hanne Leysen, Paula Santos-Otte, Richard T. Premont, Bronwen Martin, Stuart Maudsley
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Complex aging-triggered disorders are multifactorial programs that comprise a myriad of alterations in interconnected protein networks over a broad range of tissues. It is evident that rather than being randomly organized events, pathophysiologies th
Externí odkaz:
https://doaj.org/article/f635c04819c3414ea22a3db24130869d
Autor:
Jaana van Gastel, Jhana O. Hendrickx, Hanne Leysen, Paula Santos-Otte, Louis M. Luttrell, Bronwen Martin, Stuart Maudsley
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
G protein coupled receptors (GPCRs) were first characterized as signal transducers that elicit downstream effects through modulation of guanine (G) nucleotide-binding proteins. The pharmacotherapeutic exploitation of this signaling paradigm has creat
Externí odkaz:
https://doaj.org/article/3c68c331949d44138e3e3d685b2bd1aa
Autor:
Hanne Leysen, Jaana van Gastel, Jhana O. Hendrickx, Paula Santos-Otte, Bronwen Martin, Stuart Maudsley
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 10, p 2919 (2018)
G protein-coupled receptors (GPCRs) and their associated proteins represent one of the most diverse cellular signaling systems involved in both physiological and pathophysiological processes. Aging represents perhaps the most complex biological proce
Externí odkaz:
https://doaj.org/article/c44ec3f308ba451a915d8bf2d345744c
Publikováno v:
Nano Letters
Microtubules gliding on motor-functionalized surfaces have been explored for various nanotechnological applications. However, when moving over large distances (several millimeters) and long times (tens of minutes), microtubules are lost due to surfac
Autor:
Hanne Leysen, Stuart Maudsley, Jaana van Gastel, Paula Santos-Otte, Jhana O. Hendrickx, Abdelkrim Azmi, Bronwen Martin
Publikováno v:
Aging (Albany NY)
DNA damage response (DDR) processes, often caused by oxidative stress, are important in aging and -related disorders. We recently showed that G protein-coupled receptor (GPCR) kinase interacting protein 2 (GIT2) plays a key role in both DNA damage an
Autor:
Hanne Leysen, Jhana O. Hendrickx, Paula Santos-Otte, Stuart Maudsley, Jaana van Gastel, Bronwen Martin
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 17, Iss, Pp 1265-1277 (2019)
Computational and Structural Biotechnology Journal, Vol 17, Iss, Pp 1265-1277 (2019)
Aging is a complex biological process that is inevitable for nearly all organisms. Aging is the strongest risk factor for development of multiple neurodegenerative disorders, cancer and cardiovascular disorders. Age-related disease conditions are mai
Autor:
Jaana van Gastel, Hanne Leysen, Stuart Maudsley, Jens Van Turnhout, Bronwen Martin, Abdelkrim Azmi, Jasper Verswyvel, Laura Vangenechten, Paula Santos-Otte
Publikováno v:
The FASEB Journal. 35
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-7 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-7 (2020)
The plasma membrane is the interface through which cells interact with their environment. Membrane proteins are embedded in the lipid bilayer of the plasma membrane and their function in this context is often linked to their specific location and dyn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80a0aeeb5cdbda87e040a20aad78a20f