Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Paula S Samiec"'
Publikováno v:
Toxicological Sciences. 54:52-59
Glutathione S-transferases in the small intestine function in detoxification of electrophilic compounds ingested in foods, dietary supplements, and orally administered drug preparations. Although the required substrate glutathione (GSH) is synthesize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02f6f1da43f6e51427d9c7e231f5b5fa
https://doi.org/10.1093/toxsci/54.1.52
https://doi.org/10.1093/toxsci/54.1.52
Autor:
Jay I. Goodman, Paula S. Samiec
Publikováno v:
Toxicological Sciences. 49:255-262
DNA methylation (DNA-5-methylcytosine [MeC]) plays a key role in regulation of gene expression. Highly methylated genes tend to be silenced whereas hypomethylated genes have an increased potential for expression. One way in which methylation may lead
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d9e2a6d50c69e0be38e16a3d846b500
https://doi.org/10.1093/toxsci/49.2.255
https://doi.org/10.1093/toxsci/49.2.255
Autor:
Paula S Samiec, Joanne L Carlson, Paul Sternberg, Robyn L Reed, Vino C Mody, Lou Ann S. Brown, Dean P. Jones
Publikováno v:
Clinica Chimica Acta. 275:175-184
Literature values for human plasma GSH vary over 10-fold despite the use of apparently valid analytical procedures for GSH measurement. The purpose of this study was to develop a procedure to minimize error in sample collection, processing and storag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11c3f5261c24fb42bbd9c4b2e4d29c11
https://doi.org/10.1016/s0009-8981(98)00089-8
https://doi.org/10.1016/s0009-8981(98)00089-8
Autor:
John W. Eley, Elaine W. Flagg, Paula S Samiec, Lawrence J. Dahm, Ralph J. Coates, Dean P. Jones
Publikováno v:
Free Radicals: from Basic Science to Medicine ISBN: 9783034899147
The intestine is exposed continually to dietary toxicants, and it utilizes GSH and GSH-dependent enzyme systems in detoxication of these agents. Recent studies show that enterocytes take up GSH intact and use it to increase degradation of dietary lip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6c22bece1b0079d40f923960f8370e8
https://doi.org/10.1007/978-3-0348-9116-5_42
https://doi.org/10.1007/978-3-0348-9116-5_42
