Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Paula Sáez-Espinosa"'
Autor:
María José Gómez-Torres, Miranda Hernández-Falcó, Andrea López-Botella, Natalia Huerta-Retamal, Paula Sáez-Espinosa
Publikováno v:
Biomedicines, Vol 11, Iss 11, p 2872 (2023)
IZUMO1 is an acrosome transmembrane protein implicated in the adhesion and fusion of gametes. This study aims to describe the distribution of IZUMO1 in human sperm under different physiological conditions: before capacitation (NCS), at one-hour capac
Externí odkaz:
https://doaj.org/article/c92ccb8c4cb14b5cb74eeb73699a1c34
Specific lectin binding sites during in vitro capacitation and acrosome reaction in boar spermatozoa
Autor:
Laura Robles-Gómez, Leopoldo González-Brusi, Paula Sáez-Espinosa, Natalia Huerta-Retamal, Paula Cots-Rodríguez, Manuel Avilés, María José Gómez-Torres
Publikováno v:
Italian Journal of Animal Science, Vol 20, Iss 1, Pp 372-382 (2021)
Sperm glycocalyx and plasma membrane undergo outstanding modifications during fertilization. However, it is unclear how in vitro capacitation time and acrosome reaction affect the specific location of boar sperm glycoconjugates. This study aimed to i
Externí odkaz:
https://doaj.org/article/0082efcbb7674223ba38e8cba3714282
Publikováno v:
Life, Vol 13, Iss 2, p 364 (2023)
The unique properties of spermatozoa are established through the spermatogenesis and maturation processes concurrently with its epigenome. It is known that damage to epigenetic mechanisms can lead to reproductive problems. However, scientific reviews
Externí odkaz:
https://doaj.org/article/f0c200f5b00947fe8a894a6134d700cb
Autor:
Paula Sáez-Espinosa, Natalia Huerta-Retamal, Laura Robles-Gómez, Manuel Avilés, Jon Aizpurua, Irene Velasco, Alejandro Romero, María José Gómez-Torres
Publikováno v:
Asian Journal of Andrology, Vol 22, Iss 5, Pp 447-453 (2020)
A cascade of dramatic physiological events is linked to the sperm acrosome reaction and binding to the oocyte's zona pellucida during human sperm capacitation. However, structural and functional sperm changes during capacitation currently remain poor
Externí odkaz:
https://doaj.org/article/48665595a5f64fbe857da7476dfef1f2
Autor:
María José Gómez-Torres, Paula Sáez-Espinosa, Paula Manzano-Santiago, Laura Robles-Gómez, Natalia Huerta-Retamal, Jon Aizpurua
Publikováno v:
Biomedicines, Vol 10, Iss 10, p 2553 (2022)
The failures of binding to the oocyte zona pellucida are commonly attributed to defects in the sperm recognition, adhesion, and fusion molecules. SPAM1 (sperm adhesion molecule 1) is a hyaluronidase implicated in the dispersion of the cumulus-oocyte
Externí odkaz:
https://doaj.org/article/88ac9be7691641d596f6e8fdc1cbd6ba
Autor:
Miranda Hernández-Falcó, Paula Sáez-Espinosa, Andrea López-Botella, Jon Aizpurua, María José Gómez-Torres
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 3929 (2022)
Gamete membrane fusion is a critical cellular event in sexual reproduction. In addition, the generation of knockout models has provided a powerful tool for testing the functional relevance of proteins thought to be involved in mammalian fertilization
Externí odkaz:
https://doaj.org/article/39d86c3460a24400aa2fc94fe7cd5cf5
Autor:
Paula Sáez-Espinosa, Laura Robles-Gómez, Leonor Ortega-López, Jon Aizpurua, María José Gómez-Torres
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1729 (2022)
Globozoospermia is a rare and severe type of teratozoospermia characterized by the presence of round-headed, acrosomeless spermatozoa with cytoskeleton defects. Current data support a negative relationship between globozoospermia and intracytoplasmic
Externí odkaz:
https://doaj.org/article/fe1150fab4824c1683980ba445403da7
Autor:
Laura Robles-Gómez, Paula Sáez-Espinosa, Eliana Marina López-Viloria, Andrea López-Botella, Jon Aizpurua, María José Gómez-Torres
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 11947 (2021)
The modification of sperm glycocalyx is an essential process during sperm capacitation. The presence and redistribution of terminal and linked fucose have been described during in vitro capacitation in humans. However, the influence of the capacitati
Externí odkaz:
https://doaj.org/article/2205fd936f90466993c41b7bdfacc835
Autor:
Andrea López-Botella, Irene Velasco, Maribel Acién, Paula Sáez-Espinosa, José-Luis Todolí-Torró, Raquel Sánchez-Romero, María José Gómez-Torres
Publikováno v:
Antioxidants, Vol 10, Iss 9, p 1473 (2021)
Heavy metals are endocrine disruptors which interfere with processes mediated by endogenous hormones of the organism, negatively affecting endocrine functions. Some studies have correlated heavy metal exposure with male infertility. However, the numb
Externí odkaz:
https://doaj.org/article/565e0d289fc54f4194b6a1d35265351e
Autor:
María José Gómez-Torres, Natalia Huerta-Retamal, Laura Robles-Gómez, Paula Sáez-Espinosa, Jon Aizpurua, Manuel Avilés, Alejandro Romero
Publikováno v:
Cells, Vol 10, Iss 2, p 222 (2021)
Capacitation drives sperm biophysical and biochemical changes for sperm-oocyte interactions. It is a well-known fact that the molecular complex arylsulfatase A (ARSA), hyaluronidase sperm adhesion molecule 1 (SPAM1), and heat shock protein 2 (HSPA2)
Externí odkaz:
https://doaj.org/article/dac8f263a7f34e559793189c9b2e2518