Melanocytes in the skin--comparative whole transcriptome analysis of main skin cell types.

Autor: Paula Reemann, Ene Reimann, Sten Ilmjärv, Orm Porosaar, Helgi Silm, Viljar Jaks, Eero Vasar, Külli Kingo, Sulev Kõks

Publikováno v: PLoS ONE, Vol 9, Iss 12, p e115717 (2014)

Melanocytes possess several functions besides a role in pigment synthesis, but detailed characteristics of the cells are still unclear. We used whole transcriptome sequencing (RNA-Seq) to assess differential gene expression of cultivated normal human

Externí odkaz: https://doaj.org/article/8125498e1062450d852cde2b41a00b64

miR-146b Probably Assists miRNA-146a in the Suppression of Keratinocyte Proliferation and Inflammatory Responses in Psoriasis

Autor: Richard C. Trembath, H. Hermann, Alar Aab, Michael Weichenthal, Kristi Abram, Ana Rebane, Lam C. Tsoi, Mark Boldin, Beate Rückert, Ele Prans, Paulina Wawrzyniak, Egon Urgard, Ulrich Mrowietz, Jonathan Barker, Toomas Runnel, Liisi Šahmatova, Julia Maslovskaja, James T. Elder, Eric R. Tkaczyk, Uku Haljasorg, Kai Kisand, Cezmi A. Akdis, Pärt Peterson, Maire Karelson, Nathaniel Magilnick, Elke Rodriguez, Külli Kingo, Hansjörg Baurecht, Paula Reemann, Christian Gieger, Bret Kaldvee, Stephan Weidinger, Andre Franke

Publikováno v: Hermann, H, Runnel, T, Aab, A, Baurecht, H, Rodriguez, E, Magilnick, N, Urgard, E, Šahmatova, L, Prans, E, Maslovskaja, J, Abram, K, Karelson, M, Kaldvee, B, Reemann, P, Haljasorg, U, Rückert, B, Wawrzyniak, P, Weichenthal, M, Mrowietz, U, Franke, A, Gieger, C, Barker, J, Trembath, R, Tsoi, L C, Elder, J T, Tkaczyk, E R, Kisand, K, Peterson, P, Kingo, K, Boldin, M, Weidinger, S, Akdis, C A & Rebane, A 2017, ' miR-146b probably assists miRNA-146a in the suppression of keratinocyte proliferation and inflammatory responses in psoriasis ', Journal of Investigative Dermatology . https://doi.org/10.1016/j.jid.2017.05.012
J. Invest. Dermatol. 137, 1945-1954 (2017)

miR-146a inhibits inflammatory responses in human keratinocytes and in different mouse models of skin inflammation. Little is known about the role of miR-146b in the skin. In this study, we confirmed the increased expression of miR-146a and miR-146b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c3ff4c81f7c8a7bf172571c22a7f6ec
https://doi.org/10.1016/j.jid.2017.05.012

Analysis of the expression profile of CRH–POMC system genes in vitiligo skin biopsies

Autor: Eerik Aunin, Sulev Kõks, Ene Reimann, Eero Vasar, Tiit Salum, Paula Reemann, Kristi Abram, Külli Kingo, Helgi Silm, Maire Karelson

Publikováno v: Journal of Dermatological Science. 60:125-128

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c2490faf40fc86711b5e75623613211
https://doi.org/10.1016/j.jdermsci.2010.08.004

MicroRNA-155 is Dysregulated in the Skin of Patients with Vitiligo and Inhibits Melanogenesis-associated Genes in Melanocytes and Keratinocytes

Autor: Alar Aab, Ana Rebane, Kristi Abram, Maire Pihlap, Stoyan Tankov, H. Hermann, Kai Kisand, Liisi Šahmatova, Maire Karelson, Ele Prans, Külli Kingo, Paula Reemann

Publikováno v: Acta Dermato Venereologica.

Little is known about the functions of microRNAs (miRNAs) in skin pigmentation disorders. The aim of this study was to investigate the expression and potential role of miRNAs in vitiligo. Of 12 studied miRNAs with proven functions in cell proliferati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d18040f0862265af9c7b464e727a39c1
https://doi.org/10.2340/00015555-2394

Expression of Class II Cytokine Genes in Children’s Skin

Autor: Sulev Kõks, Paula Reemann, Kristi Abram, Külli Kingo, Orm Porosaar, Siim Suutre, Maarjaliis Paavo, Ulvi Loite, Ene Reimann, Helgi Silm, Eero Vasar

Publikováno v: Acta Dermato Venereologica

Immune regulation of the skin plays an important role in susceptibility and development of illnesses. The aim of our study was to localise the interleukin (IL)-10 family of cytokines, in children's skin and to determine possible age-related differenc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdd1ef2f0ac137c58e84ac00780ebeb0