Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Paula Raposinho"'
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-14 (2020)
Abstract Background Recently, a new family of 99mTc(I)-tricarbonyl complexes bearing an acridine orange (AO) DNA targeting unit and different linkers between the Auger emitter (99mTc) and the AO moiety was evaluated for Auger therapy. Among them, 99m
Externí odkaz:
https://doaj.org/article/5680275189514e088a79bc5cebe60e27
Autor:
Alice D’Onofrio, Francisco Silva, Lurdes Gano, Paula Raposinho, Célia Fernandes, Arkadiusz Sikora, Monika Wyczółkowska, Renata Mikołajczak, Piotr Garnuszek, António Paulo
Publikováno v:
Pharmaceutics, Vol 14, Iss 12, p 2569 (2022)
Several gastrin-releasing peptide receptor (GRPR) antagonists with improved in vivo behavior have been recently developed and tested in the clinic. However, despite the generally mild side effects of peptide receptor radionuclide therapy (PRRT), toxi
Externí odkaz:
https://doaj.org/article/be3a8061859940269765896c9e48ff68
Autor:
Célia Fernandes, Elisa Palma, Francisco Silva, Ana Belchior, Catarina I. G. Pinto, Joana F. Guerreiro, Hugo M. Botelho, Filipa Mendes, Paula Raposinho, António Paulo
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 7238 (2022)
Although 99mTc is not an ideal Auger electron (AE) emitter for Targeted Radionuclide Therapy (TRT) due to its relatively low Auger electron yield, it can be considered a readily available “model” radionuclide useful to validate the design of new
Externí odkaz:
https://doaj.org/article/aa7fbeed660f4a59a2a048a27598af64
Autor:
Francisco Silva, Alice D’Onofrio, Carolina Mendes, Catarina Pinto, Ana Marques, Maria Paula Cabral Campello, Maria Cristina Oliveira, Paula Raposinho, Ana Belchior, Salvatore Di Maria, Fernanda Marques, Carla Cruz, Josué Carvalho, António Paulo
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 2, p 617 (2022)
Despite some progress, the overall survival of patients with glioblastoma (GBM) remains extremely poor. In this context, there is a pressing need to develop innovative therapy strategies for GBM, namely those based on nanomedicine approaches. Towards
Externí odkaz:
https://doaj.org/article/099133757a3e45babeb6c79feefab992
Autor:
Diogo Figueiredo, Célia Fernandes, Francisco Silva, Elisa Palma, Paula Raposinho, Ana Belchior, Pedro Vaz, António Paulo
Publikováno v:
Molecules, Vol 26, Iss 2, p 441 (2021)
For effective Auger therapy of cancer, the Auger-electron emitters must be delivered to the tumor cells in close proximity to a radiosensitive cellular target. Nuclear DNA is considered the most relevant target of Auger electrons to have augmented ra
Externí odkaz:
https://doaj.org/article/f7bff5e5207f44f1b10a0680c2e9fbc6
Autor:
Elisabetta Gabano, Letícia do Quental, Elena Perin, Francisco Silva, Paula Raposinho, António Paulo, Mauro Ravera
Publikováno v:
Inorganics, Vol 6, Iss 1, p 4 (2017)
New chitosan derivatives modified with (3-carboxypropyl)trimethylammonium chloride (1) and coupled with (OC-6-44)-diammine(4-carboxypropanoato)dichloridoethanolatoplatinum(IV) (2), were synthesized and their preliminary biological evaluation carried
Externí odkaz:
https://doaj.org/article/45990906620346e0ba94276ca1fb9404
Autor:
Célia Fernandes, Joana Santos, Maria Braz, Francisco Silva, Paula Raposinho, Joana Guerreiro, Frederik Cleeren, Irwin Cassells, Filipa Mendes, António Paulo
Publikováno v:
Nuclear Medicine and Biology. :S51-S52
Autor:
Paula Raposinho, Francisco Silva, Alice D’Onofrio, Carolina Mendes, Maria Paula Campello, Maria Cristina Oliveira, Ana Belchior, Fernanda Marques, António Paulo
Publikováno v:
Nuclear Medicine and Biology. :S30
Autor:
Lurdes Gano, Alice D’Onofrio, Francisco Silva, Paula Raposinho, Arkadiusz Sikora, Monika Orzełowska, Renata Mikołajczak, Piotr Garnuszek, António Paulo
Publikováno v:
Nuclear Medicine and Biology. :S30
Autor:
Alice D’Onofrio, Francisco Silva, Lurdes Gano, Paula Raposinho, Arkadiusz Sikora, Monika Orzełowska, Renata Mikołajczak, Piotr Garnuszek, António Paulo
Publikováno v:
Nuclear Medicine and Biology. :S188