Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Paula Potter"'
Autor:
Hayley Farmer, Timothy H Ward, Andrew Taylor, Helen Turner, Nita Fisher, Danielle Shaw, Gordon C Jayson, Mark N. K. Saunders, Nigel K Smith, Caleb Roberts, Sarah Halford, Yvonne Watson, Andrew R Clamp, Laura Horsley, Jeffrey Cummings, Paula Potter, Mark R. Middleton, Caroline Dive, Philip J. Hogg, Geoff J M Parker, Gireesh C Kumaran, Ross A. Little, Jurjees Hasan, Adrian L. Harris, Alison Backen, Gavin Halbert, Martin J Dawson, Jon Smythe
Publikováno v:
Cancer Chemotherapy and Pharmacology. 72:1343-1352
Background: 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO) is a water-soluble mitochondrial toxin that binds to adenine nucleotide translocase in the inner mitochondrial membrane, thereby targeting cell proliferation. This phase 1 study in
Autor:
Sue Francis-McIntyre, Stephen Chew-Graham, John N. Haselden, Frederick C. W. Wu, Catriona McWhirter, Joshua Knowles, Gill Aarons, Ian D. Wilson, Steve O'Hagan, Paula Potter, Gordon C Jayson, Marie Brown, David I. Ellis, Eva Zelena, Paula Thornton, Nitin Purandare, Andrew W. Nicholls, Boben Benjamin, Warwick B. Dunn, Nadine Harding, J. Kennedy Cruickshank, Wanchang Lin, Andy Tseng, David Broadhurst, Catherine L. Winder, Alistair Burns, Catherine Potts, Paul Begley, Martin Pan, Carly Moseley, Royston Goodacre, J. D. Finn, Andrew A. Vaughan, Douglas B. Kell, Mohammed Zubair, Antony Halsall
Publikováno v:
Metabolomics
Dunn, W, Lin, W, Broadhurst, D, Begley, P, Brown, M, Zelena, E, Vaughan, A, Halsall, A, Harding, N, Knowles, J, Francis-McIntyre, S, Tseng, A, Ellis, D, O'Hagan, S, Aarons, G, Benjamin, B, Chew-Graham, S, Moseley, C, Potter, P, Winder, C, Potts, C, Thornton, P, McWhirter, C, Zubair, M, Pan, M, Burns, A, Cruickshank, K, Jayson, G, Purandare, N, Wu, FC, Finn, J, Haselden, JN, Nicholls, AW, Wilson, ID, Goodacre, R & Kell, D 2015, ' Molecular phenotyping of a UK population : defining the human serum metabolome ' Metabolomics, vol. 11, no. 1, pp. 9-26 . https://doi.org/10.1007/s11306-014-0707-1
Dunn, W, Lin, W, Broadhurst, D, Begley, P, Brown, M, Zelena, E, Vaughan, A, Halsall, A, Harding, N, Knowles, J, Francis-McIntyre, S, Tseng, A, Ellis, D, O'Hagan, S, Aarons, G, Benjamin, B, Chew-Graham, S, Moseley, C, Potter, P, Winder, C, Potts, C, Thornton, P, McWhirter, C, Zubair, M, Pan, M, Burns, A, Cruickshank, K, Jayson, G, Purandare, N, Wu, FC, Finn, J, Haselden, JN, Nicholls, AW, Wilson, ID, Goodacre, R & Kell, D 2015, ' Molecular phenotyping of a UK population : defining the human serum metabolome ', Metabolomics, vol. 11, no. 1, pp. 9-26 . https://doi.org/10.1007/s11306-014-0707-1
Dunn, W, Lin, W, Broadhurst, D, Begley, P, Brown, M, Zelena, E, Vaughan, A, Halsall, A, Harding, N, Knowles, J, Francis-McIntyre, S, Tseng, A, Ellis, D, O'Hagan, S, Aarons, G, Benjamin, B, Chew-Graham, S, Moseley, C, Potter, P, Winder, C, Potts, C, Thornton, P, McWhirter, C, Zubair, M, Pan, M, Burns, A, Cruickshank, K, Jayson, G, Purandare, N, Wu, FC, Finn, J, Haselden, JN, Nicholls, AW, Wilson, ID, Goodacre, R & Kell, D 2015, ' Molecular phenotyping of a UK population : defining the human serum metabolome ' Metabolomics, vol. 11, no. 1, pp. 9-26 . https://doi.org/10.1007/s11306-014-0707-1
Dunn, W, Lin, W, Broadhurst, D, Begley, P, Brown, M, Zelena, E, Vaughan, A, Halsall, A, Harding, N, Knowles, J, Francis-McIntyre, S, Tseng, A, Ellis, D, O'Hagan, S, Aarons, G, Benjamin, B, Chew-Graham, S, Moseley, C, Potter, P, Winder, C, Potts, C, Thornton, P, McWhirter, C, Zubair, M, Pan, M, Burns, A, Cruickshank, K, Jayson, G, Purandare, N, Wu, FC, Finn, J, Haselden, JN, Nicholls, AW, Wilson, ID, Goodacre, R & Kell, D 2015, ' Molecular phenotyping of a UK population : defining the human serum metabolome ', Metabolomics, vol. 11, no. 1, pp. 9-26 . https://doi.org/10.1007/s11306-014-0707-1
Phenotyping of 1,200 ‘healthy’ adults from the UK has been performed through the investigation of diverse classes of hydrophilic and lipophilic metabolites present in serum by applying a series of chromatography–mass spectrometry platforms. The