Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Paula Maloberti"'
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 11, Pp 1936-1948 (2011)
Acyl-CoA synthetase 4 (ACSL4) is implicated in fatty acid metabolism with marked preference for arachidonic acid (AA). ACSL4 plays crucial roles in physiological functions such as steroid synthesis and in pathological processes such as tumorigenesis.
Externí odkaz:
https://doaj.org/article/868a03c898eb42aa98f39958dbc51eb3
Autor:
Cecilia Poderoso, Daniela P Converso, Paula Maloberti, Alejandra Duarte, Isabel Neuman, Soledad Galli, Fabiana Cornejo Maciel, Cristina Paz, María C Carreras, Juan J Poderoso, Ernesto J Podestá
Publikováno v:
PLoS ONE, Vol 3, Iss 1, p e1443 (2008)
ERK1/2 is known to be involved in hormone-stimulated steroid synthesis, but its exact roles and the underlying mechanisms remain elusive. Both ERK1/2 phosphorylation and steroidogenesis may be triggered by cAMP/cAMP-dependent protein kinase (PKA)-dep
Externí odkaz:
https://doaj.org/article/7972500005b64f22bf69cc9dc339b6c8
Autor:
Paula Maloberti, María T. Torres, Facundo José Salinas, Natalia Raquel Salvetti, Pablo Lorenzano Menna, Graciela Caroca, Daniel E. Gomez, Ulises Daniel Orlando, María Mercedes Bigi, Hugo Hector Ortega, Jesica Giselle Prada, Ana Fernanda Castillo, Juan B. Rodriguez, Angela Rosario Solano, Melina Andrea Dattilo, Belkis Ester Marelli, Mayra Agustina Ríos Medrano, Ernesto J. Podestá, Sebastián Indo, Sergio H. Szajnman, Héctor R. Contreras
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Acyl-CoA synthetase 4 (ACSL4) is an isoenzyme of the fatty acid ligase-coenzyme-A family taking part in arachidonic acid metabolism and steroidogenesis. ACSL4 is involved in the development of tumor aggressiveness in breast and prostate tumors throug
Autor:
Paula Maloberti, Melina Andrea Dattilo, Ernesto J. Podestá, Yanina Benzo, Ulises Daniel Orlando, Lucía Manuela Herrera, Jesica Giselle Prada, Ana Fernanda Castillo
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Scientific Reports
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Scientific Reports
Acyl-CoA synthetase 4 (ACSL4) overexpression plays a causal role in the aggressiveness of triple negative breast cancer. In turn, a negative correlation has been established between ACSL4 and estrogen receptor alpha (ERα) expression. However, the up
Autor:
Yanina Benzo, Mercedes Lasaga, Cristina Paz, Melina Andrea Dattilo, Lucía Manuela Herrera, Carla Mariana Caruso, Paula Maloberti, Paula Fernanda Lopez, Jesica Giselle Prada, Corina I. García
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 208
Acyl-CoA synthetase 4 (Acsl4), an enzyme involved in arachidonic acid (AA) metabolism, participates in physiological and pathological processes such as steroidogenesis and cancer. The role of Acsl4 in neurons and in nervous system development has als
Autor:
Alejandra Gorostizaga, Juan José López-Costa, Carlos F. Mendez, Cristina Paz, Andrea Acquier, Paula Maloberti, Mercedes Mori Sequeiros García
Publikováno v:
Journal of Cellular Biochemistry. 117:2170-2181
Adrenocorticotropic hormone (ACTH) treatment has been proven to promote paxillin dephosphorylation and increase soluble protein tyrosine phosphatase (PTP) activity in rat adrenal zona fasciculata (ZF). Also, in-gel PTP assays have shown the activatio
Autor:
Silvana I. Nudler, Carlos F. Mendez, Cristina Paz, Mercedes Mori Sequeiros García, Pablo G. Mele, Paula Maloberti, Juan M. Cohen Sabban, Melina Andrea Dattilo
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Heliyon, Vol 6, Iss 3, Pp e03519-(2020)
Heliyon
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Heliyon, Vol 6, Iss 3, Pp e03519-(2020)
Heliyon
MAPK phosphatases (MKP) downregulate the activity of mitogen-activated protein kinases (MAPK), such as ERK1/2, and modulate the processes regulated by these kinases. ERK1/2 participate in a wide range of processes including tissue-specific hormone-st
Autor:
Paula Maloberti, Mayra Agustina Ríos Medrano, Angela R. Solano, Ulises Daniel Orlando, Ana Fernanda Castillo, Ernesto J. Podestá
Publikováno v:
Biochemical pharmacology. 159
Acyl-CoA synthetase-4 (ACSL4) is an enzyme implicated in estrogen receptor α (ERα) negative regulation and hormone therapy resistance in breast cancer. In addition, ACSL4 has been associated to certain types of hormone resistance in prostate cancer
Publikováno v:
Molecular and Cellular Endocrinology. 371:71-78
Hormonal regulation of steroidogenesis involves arachidonic acid (AA) metabolism through the 5-lipoxygenase pathway. One of the products, 5-hydroperoxy-eicosatetraenoic acid (5-HpETE), acts as a modulator of the activity of the steroidogenic acute re
Autor:
Paula Maloberti, Ana Fernanda Castillo, Ernesto J. Podestá, Paula Fernanda Lopez, Ulises D Orl, Angela R. Solano
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Aim: Breast cancer comprises a heterogeneous group of diseases that vary in morphology, biology, behavior and response to therapy. Previous studies have identified an acyl-CoA synthetase 4 (ACSL4) gene-expression pattern correlated with very aggressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14b6e8121392d2ee9085715ebb19de66
https://www.esciencecentral.org/journals/gene-expression-profile-and-signaling-pathways-in-mcf7-breast-cancercells-mediated-by-acylcoa-synthetase-4-overexpression-2329-8936-1000120.php?aid=65696
https://www.esciencecentral.org/journals/gene-expression-profile-and-signaling-pathways-in-mcf7-breast-cancercells-mediated-by-acylcoa-synthetase-4-overexpression-2329-8936-1000120.php?aid=65696