Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Paula M. van Heijningen"'
Autor:
Marjolijn Renard, Bram Trachet, Christophe Casteleyn, Laurence Campens, Pieter Cornillie, Bert Callewaert, Steven Deleye, Bert Vandeghinste, Paula M van Heijningen, Harry Dietz, Filip De Vos, Jeroen Essers, Steven Staelens, Patrick Segers, Bart Loeys, Paul Coucke, Anne De Paepe, Julie De Backer
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89749 (2014)
Loeys-Dietz syndrome (LDS) is an autosomal dominant arterial aneurysm disease belonging to the spectrum of transforming growth factor β (TGFβ)-associated vasculopathies. In its most typical form it is characterized by the presence of hypertelorism,
Externí odkaz:
https://doaj.org/article/b75c363598d6443c995fbd08ab7f6f85
Autor:
Natasja W M Ramnath, Koen M van de Luijtgaarden, Ingrid van der Pluijm, Menno van Nimwegen, Paula M van Heijningen, Sigrid M A Swagemakers, Bibi S van Thiel, Ruziedi Y Ridwan, Nicole van Vliet, Marcel Vermeij, Luuk J A C Hawinkels, Anne de Munck, Oleh Dzyubachyk, Erik Meijering, Peter van der Spek, Robbert Rottier, Hiromi Yanagisawa, Rudi W Hendriks, Roland Kanaar, Ellen V Rouwet, Alex Kleinjan, Jeroen Essers
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106054 (2014)
BackgroundIn this study we set out to investigate the clinically observed relationship between chronic obstructive pulmonary disease (COPD) and aortic aneurysms. We tested the hypothesis that an inherited deficiency of connective tissue might play a
Externí odkaz:
https://doaj.org/article/54e4a897fc8f4940a384b4aa95d8a42b
Autor:
Hiromi Yanagisawa, Gert W. A. van Cappellen, Paula M. van Heijningen, Maria M. Alves, Gert-Jan Kremers, Roland Kanaar, Jeroen Essers, Dieter P. Reinhardt, Nicole van Vliet, Joyce Burger, Heena Kumra, Ingrid van der Pluijm
Publikováno v:
Cellular Signalling, 58, 65-78. Elsevier Inc.
Fibulin-4 is an extracellular matrix (ECM) protein essential for elastogenesis and mutations in this protein lead to aneurysm formation. In this study, we isolated vascular smooth muscle cells (VSMCs) from mice with reduced fibulin-4 protein expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::005dc473f20df19f20e1e6448e5e73e3
https://pure.eur.nl/en/publications/07e5208c-964e-4244-93d7-43b4a1ea37ae
https://pure.eur.nl/en/publications/07e5208c-964e-4244-93d7-43b4a1ea37ae
Autor:
Chiara Milanese, Reinier van der Linden, Jeroen Demmers, Ivo Que, Luuk te Riet, Roland Kanaar, Joyce Burger, Devashish Das, Kees Schoonderwoerd, Elaine C. Davis, Elena Gallo MacFarlane, Erik L. Kaijzel, Marcel Vermeij, Ingrid van der Pluijm, Pier G. Mastroberardino, Arne S. IJpma, Lea Jeanne Ringuette, Hiromi Yanagisawa, Paula M. van Heijningen, Harry C. Dietz, Nicole van Vliet, Jeroen Essers, Willem Sluiter, D. H. W. Dekkers
Publikováno v:
Cardiovascular Research
Cardiovascular Research, 114(13), 1776-1793
Cardiovascular Research, 114(13), 1776-1793. Oxford University Press
Cardiovascular Research, 114(13), 1776-1793. OXFORD UNIV PRESS
Cardiovascular Research, 114(13), 1776-1793
Cardiovascular Research, 114(13), 1776-1793. Oxford University Press
Cardiovascular Research, 114(13), 1776-1793. OXFORD UNIV PRESS
Aim Thoracic aortic aneurysms are a life-threatening condition often diagnosed too late. To discover novel robust biomarkers, we aimed to better understand the molecular mechanisms underlying aneurysm formation.Methods and results In Fibulin-4(R/R) m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::640183c507e732545aaebb83d2b68113
https://doi.org/10.1093/cvr/cvy150
https://doi.org/10.1093/cvr/cvy150
Autor:
Els Moltzer, Luuk te Riet, Sigrid M A Swagemakers, Paula M van Heijningen, Marcel Vermeij, Richard van Veghel, Angelique M Bouhuizen, Joep H M van Esch, Stephanie Lankhorst, Natasja W M Ramnath, Monique C de Waard, Dirk J Duncker, Peter J van der Spek, Ellen V Rouwet, A H Jan Danser, Jeroen Essers
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23411 (2011)
Medial degeneration is a key feature of aneurysm disease and aortic dissection. In a murine aneurysm model we investigated the structural and functional characteristics of aortic wall degeneration in adult fibulin-4 deficient mice and the potential t
Externí odkaz:
https://doaj.org/article/a6d2781360ab45bdb123a75a928f35cd
Autor:
Wim Vos, Franco Fabio Stellari, Sasha Belenkov, Francesca Ravanetti, Jeroen Essers, Yanto Ridwan, Francesca Ruscitti, Antonio Cacchioli, Francisca Ferreira, Paula M. van Heijningen, Cedric Van Holsbeke, Gino Villetti, Alex KleinJan
Publikováno v:
Multidisciplinary Respiratory Medicine, 12:8. BioMed Central Ltd.
Multidisciplinary Respiratory Medicine
Multidisciplinary Respiratory Medicine, Vol 12, Iss 1, Pp 1-10 (2017)
Multidisciplinary Respiratory Medicine
Multidisciplinary Respiratory Medicine, Vol 12, Iss 1, Pp 1-10 (2017)
The intratracheal instillation of bleomycin in mice induces early damage to alveolar epithelial cells and development of inflammation followed by fibrotic tissue changes and represents the most widely used model of pulmonary fibrosis to investigate h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33132253423d68cca67a0343a6922c7a
https://pure.eur.nl/en/publications/c3a3adf5-753a-4e84-8db1-efce379bc616
https://pure.eur.nl/en/publications/c3a3adf5-753a-4e84-8db1-efce379bc616
Autor:
Eric L. Kaijzel, Alan Chan, Natasja W. M. Ramnath, Clemens W.G.M. Löwik, Jouke Dijkstra, Gerben A. Koning, Piotr A. Wielopolski, Marcel Vermeij, Wiggert A. van Cappellen, Monique R. Bernsen, Ivo Que, Jeroen Essers, Lukas J. A. C. Hawinkels, Paula M. van Heijningen
Publikováno v:
Circulation: Cardiovascular Imaging, 3(5), 567-577
Circulation Cardiovascular Imaging, 3(5), 567-577. Lippincott Williams & Wilkins
Circulation Cardiovascular Imaging, 3(5), 567-577. Lippincott Williams & Wilkins
Background— We imaged the protease activity of matrix metalloproteinases (MMPs) upregulated during aneurysm formation, using protease-activatable near-infrared fluorescence probes. We tested whether these protease-activatable sensors can directly r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8c249e441ad011ccc3c6bba223360b3
https://doi.org/10.1161/circimaging.109.933093
https://doi.org/10.1161/circimaging.109.933093
Autor:
Jeroen Essers, Yanto Ridwan, Elza D. van Deel, Luuk te Riet, Els Moltzer, A.H. Jan Danser, Ingrid M. Garrelds, Paula M. van Heijningen, Bibi S. van Thiel, Jan Lukas Robertus, Richard van Veghel, Nicole van Vliet, Marcel Vermeij, Ingrid van der Pluijm
Publikováno v:
Journal of Hypertension, 34(4), 654-665. Lippincott Williams & Wilkins
textabstractAims: Increasing evidence supports a role for the angiotensin II-AT 1 -receptor axis in aneurysm development. Here, we studied whether counteracting this axis via stimulation of AT 2 receptors is beneficial. Such stimulation occurs natura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf5872d9eebfd9ef16cd64db29314bb7
https://pure.eur.nl/en/publications/748ff325-cd90-45da-a1da-b909ab28ae1f
https://pure.eur.nl/en/publications/748ff325-cd90-45da-a1da-b909ab28ae1f
Autor:
Ruziedi Y. Ridwan, Natasja W. M. Ramnath, Jeroen Essers, Erik Meijering, Hiromi Yanagisawa, Roland Kanaar, Marcel Vermeij, Ingrid van der Pluijm, Alex KleinJan, Rudi W. Hendriks, Sigrid M. A. Swagemakers, Luuk J. A. C. Hawinkels, Paula M. van Heijningen, Koen M. van de Luijtgaarden, Ellen V. Rouwet, Robbert J. Rottier, Nicole van Vliet, Bibi S. van Thiel, Peter J. van der Spek, Menno van Nimwegen, Anne de Munck, Oleh Dzyubachyk
Publikováno v:
PLoS One (print), 9(9):e 106054. Public Library of Science
EUR Research Portal
PLoS ONE
PLoS ONE, 9(9)
PLoS ONE, Vol 9, Iss 9, p e106054 (2014)
EUR Research Portal
PLoS ONE
PLoS ONE, 9(9)
PLoS ONE, Vol 9, Iss 9, p e106054 (2014)
BackgroundIn this study we set out to investigate the clinically observed relationship between chronic obstructive pulmonary disease (COPD) and aortic aneurysms. We tested the hypothesis that an inherited deficiency of connective tissue might play a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc711237a68f0595e716d82bf62e57b5
https://hdl.handle.net/1887/103768
https://hdl.handle.net/1887/103768
Autor:
Paul Coucke, Jeroen Essers, Steven Staelens, Harry C. Dietz, Paula M. van Heijningen, Marjolijn Renard, Bert Vandeghinste, Bart Loeys, Julie De Backer, Bert Callewaert, Christophe Casteleyn, Pieter Cornillie, Steven Deleye, Bram Trachet, Anne De Paepe, Filip De Vos, Patrick Segers, Laurence Campens
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89749 (2014)
PLoS One (print), 9(2). Public Library of Science
PLoS ONE
PLOS ONE
PLoS One (print), 9(2). Public Library of Science
PLoS ONE
PLOS ONE
Loeys-Dietz syndrome (LDS) is an autosomal dominant arterial aneurysm disease belonging to the spectrum of transforming growth factor beta (TGF beta)-associated vasculopathies. In its most typical form it is characterized by the presence of hypertelo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e53e6db6cffaac043933838adf58e9dc
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24587008/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24587008/?tool=EBI