Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Paula M. Robison"'
Autor:
Patrick C. May, Paula M. Robison
Publikováno v:
Neuroscience Letters. 152:169-172
Glutamate excitotoxicity is mediated by both N- methyl- d -aspartate (NMDA)-receptor and non-NMDA receptor (α-amino-3-hydroxy-5-methyl-isoxazolepropionate (AMPA)/kainate (KA)) mechanisms but the lack of specific antagonists has limited the character
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4f9fbb0cbc47aff15058e1116b3e9aa
https://doi.org/10.1016/0304-3940(93)90510-r
https://doi.org/10.1016/0304-3940(93)90510-r
Publikováno v:
Neuroscience Letters. 262:219-221
Glutamate excitotoxicity has been implicated in a variety of acute and chronic neurodegenerative diseases but early phase clinical trials with competitive antagonists at both N -methyl- d -aspartate (NMDA)-receptors and α -amino-3-hydroxy-5-methyl-i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a78ae8af5f99779458552c90938a152b
https://doi.org/10.1016/s0304-3940(99)00084-1
https://doi.org/10.1016/s0304-3940(99)00084-1
Autor:
Patrick C. May, Paula M. Robison, Gerald W. Becker, Diane C. Waters, Jennifer S. Small, Bruce D. Gitter, Linda K. Simmons
Publikováno v:
Neurobiology of Aging. 13:605-607
beta A4 peptide (beta AP) accumulates in amyloid plaques of Alzheimer's disease and may contribute to neuronal degeneration. Conflicting observations have been reported regarding the direct in vitro and in vivo neurotoxicity of beta AP. We have asses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93e210cfe2fc0da2389ce2f58bb2fcca
https://doi.org/10.1016/0197-4580(92)90064-5
https://doi.org/10.1016/0197-4580(92)90064-5
Publikováno v:
Brain research. 608(2)
We have studied amyloid precursor protein (APP) expression in rat brain following transient global ischemia. Ischemic damage 24 h after 30 min of four-vessel occlusion (4VO) was limited to the caudate nucleus; hippocampal pyramidal neurons appeared h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef34238a14f9660cbd2989973b15c085
https://pubmed.ncbi.nlm.nih.gov/8495367
https://pubmed.ncbi.nlm.nih.gov/8495367
Autor:
Paula M. Robison, Patrick C. May
Publikováno v:
Journal of neurochemistry. 60(3)
Mechanisms of non-NMDA receptor-mediated excitotoxicity were studied in embryonic rat hippocampal cultures using kainic acid (KA) and alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) as agonists. Under basal culture conditions, overni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c5438418daec0c4afb61eded554426a
https://pubmed.ncbi.nlm.nih.gov/7679725
https://pubmed.ncbi.nlm.nih.gov/7679725
Autor:
Paula M. Robison, James A. Clemens, Barry Smalstig, Kimberly S. Fuson, Diane T. Stephenson, Patrick C. May
Publikováno v:
Brain research. Molecular brain research. 15(1-2)
Sulfated glycoprotein-2 (SGP-2) is emerging as a prominent marker of neurodegeneration in mammalian brain. Regulation of brain SGP-2 was studied in adult male Wistar rats subjected to 30 min of forebrain ischemia by four vessel occlusion. By 3 days a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f672cc312dadbd42c294ded019e38518
https://pubmed.ncbi.nlm.nih.gov/1279348
https://pubmed.ncbi.nlm.nih.gov/1279348