Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Paula M. Martikainen"'
Autor:
Teuvo L.J. Tammela, Jorma Isola, Mirja Ruutu, Markus Mildh, Martti Ala-Opas, Tapio Visakorpi, Anssi Auvinen, Liisa Määttänen, Paula M. Martikainen, Tiina Luukkaala, Marita Laurila
Publikováno v:
International Journal of Cancer. 124:547-552
Prostate cancer aggressiveness was evaluated based on pathologic characterization of cases detected in the Finnish prostate cancer screening trial. The trial population consists of 80,458 men aged 55-67 years. A total of 32,000 men were randomized to
Autor:
Joonas Mikkonen, Hanne Juuti, Minna Kellomäki, Andres Kotsar, Martti Talja, Pertti Törmälä, Paula M. Martikainen, Teuvo L.J. Tammela, Taina Isotalo
Publikováno v:
Journal of Endourology. 22:1065-1070
The biodegradable PLGA (a copolymer of L-lactide and glycolide) urethral stent with a spiral configuration has been used clinically for the prevention of postoperative urinary retention after different types of thermal therapy for benign prostatic hy
Autor:
Martti Talja, Ilkka Uurto, Pertti Törmälä, Joonas Mikkonen, Juha-Pekka Salenius, Teuvo L.J. Tammela, Taina Isotalo, Andres Kotsar, Minna Kellomäki, Paula M. Martikainen
Publikováno v:
Journal of Materials Science: Materials in Medicine. 18:1543-1547
Drug-eluting stents are a recent innovation for endovascular and endourethral purposes. The aim of this study was to assess the biocompatibility of new biodegradable drug-eluting stent materials in vivo. Rods made of SR-PLDLA (self-reinforced poly-96
Autor:
Matti Hakama, Harri Juusela, Liisa Määttänen, Mirja Ruutu, Martti Ala-Opas, Teuvo L.J. Tammela, Anssi Auvinen, U.H. Stenman, Paula M. Martikainen
Publikováno v:
British Journal of Cancer
Specificity constitutes a component of validity for a screening test. The number of false-positive (FP) results has been regarded as one of major shortcomings in prostate cancer screening. We estimated the specificity of serum prostate-specific antig
Autor:
L. Shatkina, Outi R. Saramäki, Robert L. Vessella, Paula M. Martikainen, Tapio Visakorpi, H. E. Mäki, Teuvo L.J. Tammela, W.M. Van Weerden, Andrew C.B. Cato
Publikováno v:
The Journal of Pathology. 212:395-401
BAG-1L (Bcl-2-associated anthanogene 1) has been found to interact with androgen receptor (AR), and has been suggested to be involved in the development of prostate cancer. In order to determine the presence of genetic and/or expression alterations o
Autor:
Merja Bläuer, Heimo Syvälä, Paula M. Martikainen, M C Perttu, Teuvo L.J. Tammela, Heini Huhtala, Pentti Tuohimaa
Publikováno v:
Prostate Cancer and Prostatic Diseases. 9:185-189
Alterations have been demonstrated in ligand and cognate receptor system of the transforming growth factor beta (TGF-beta) pathway in prostate cancer (PC). Still, little is known about changes in the activity of the intracellular Smad cascade of TGF-
Autor:
Marita Laurila, Carlos Santonja, Robert F. Hoedemaeker, Theodorus H. van der Kwast, Stefano Ciatto, Vera Nelen, Fritz H. Schröder, Monique J. Roobol, Liisa Määtänen, Sue Moss, Simonetta Di Lollo, Jonas Hugosson, Carl-Gustaph Pihl, Paula M. Martikainen, I. Neetens
Publikováno v:
International Journal of Cancer, 118(10), 2538-2542. Wiley-Liss Inc.
Screening for prostate cancer using prostate-specific antigen (PSA) tests has led to a stage and grade shift as compared to the pre-PSA era. Effectiveness of screening for prostate cancer should be manifested by a reduction in detection rate of aggre
Publikováno v:
Virchows Archiv. 448:52-58
In this study expression of claudins 1, 3, 4 and 5 were studied in 118 cases of gastric carcinoma and compared with proliferation, apoptosis and E-cadherin expression. Expression of all these claudins could be seen in gastric carcinoma, most prominen
Autor:
Paula M. Martikainen, Tapio Visakorpi, Hanna E. Rauhala, Teemu Tolonen, Teuvo L.J. Tammela, Kati P. Porkka
Publikováno v:
International Journal of Cancer. 117:738-745
Inactivation of tumor suppressor genes through deletion, mutation and epigenetic silencing has been shown to occur in cancer. In our study, we combined DNA demethylation and histone deacetylation inhibition treatments with suppression subtraction hyb
Membranous location of EGFR immunostaining is associated with good prognosis in renal cell carcinoma
Autor:
H. Helin, Pasi Hirvikoski, Jukka Kallio, Teuvo L.J. Tammela, Tiina Luukkaala, P-L Kellokumpu-Lehtinen, Paula M. Martikainen
Publikováno v:
British Journal of Cancer
Epidermal growth factor receptor (EGFR) is a key factor in tumorigenesis. The association between EGFR expression and prognosis in renal cell carcinoma (RCC) is not clear. In our study of 134 RCCs, the cellular location of immunostaining was evaluate