Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Paula M. Gilmore"'
Publikováno v:
Human Immunology. 68:128-134
A KIR2DS4 deletion variant allele, previously identified through killer immunoglobulinlike receptor (KIR) polymerase chain reaction-sequence-specific oligonucleotide probe (PCR-SSOP) typing, was functionally investigated using an in vitro cell line m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ac7df41a0298dddd64e4cb1f66e5ff4
https://doi.org/10.1016/j.humimm.2006.12.007
https://doi.org/10.1016/j.humimm.2006.12.007
Autor:
Jennifer E. Quinn, Paula M. Gilmore, Richard D. Kennedy, Michael Carty, Paul B. Mullan, Denis Paul Harkin, Heather N. Andrews, Nuala McCabe
Publikováno v:
Biochemical Society Transactions. 31:257-262
BRCA1 (breast-cancer susceptibility gene 1) is a tumour suppressor gene that is mutated in the germline of women with a genetic predisposition to breast and ovarian cancer. In this review, we examine the role played by BRCA1 in mediating the cellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d3bf3fce9730739622c5ec266732757
https://doi.org/10.1042/bst0310257
https://doi.org/10.1042/bst0310257
Autor:
Daniel A. Haber, Nuala McCabe, Amy J. Pace, Paul B. Mullan, Heather N. Andrews, Stewart McWilliams, Patrick G. Johnston, Beverly H. Koller, D. Paul Harkin, Jennifer E. Quinn, Paula M. Gilmore, Šárka Šebelová
Publikováno v:
Journal of Biological Chemistry. 277:26225-26232
BRCA1 is a tumor suppressor gene implicated in transcriptional regulation. We have generated cell lines with inducible expression of BRCA1 as a tool to identify downstream targets that may be important mediators of BRCA1 function. Oligonucleotide arr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db037831379704e8b36d9f0d628b19d6
https://doi.org/10.1074/jbc.m201316200
https://doi.org/10.1074/jbc.m201316200
Autor:
D. Paul Harkin, Jennifer E. Quinn, Kwak Eunice L, Kenneth H. Moberg, Daphne W. Bell, Daniel A. Haber, Iswar K. Hariharan, Paula M. Gilmore, Doke C.R. Wahrer, Colin A. Graham
Publikováno v:
Gynecologic oncology. 98(1)
Objective. Archipelago (AGO, also known as hCdc4, Fbw7, or Sel-10) is an F-box containing component of the SCF complex implicated in the ubiquitination and proteolysis of cyclin E and c-Myc, and found to be mutated in 16% of endometrial carcinomas. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a27dad0ab663b5f3bdafac9392210696
https://pubmed.ncbi.nlm.nih.gov/15913747
https://pubmed.ncbi.nlm.nih.gov/15913747
Autor:
Paul B. Mullan, Jennifer E. Quinn, Nuala McCabe, Richard D. Kennedy, Stewart McWilliams, Michael Carty, W. Paul Duprex, Edison T. Liu, Julia J. Gorski, D. Paul Harkin, Patrick G. Johnston, Heather N. Andrews, Paula M. Gilmore
Publikováno v:
Cancer research. 64(12)
BRCA1 has been implicated in a number of cellular processes, including transcriptional regulation, DNA damage repair, cell cycle arrest, and apoptosis. We identified mitogen-activated protein kinase (MAPK) kinase kinase 3 (MEKK3), an upstream regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::096c1824a75420aed6793e19abc39ff5
https://pubmed.ncbi.nlm.nih.gov/15205325
https://pubmed.ncbi.nlm.nih.gov/15205325
Autor:
Jennifer E, Quinn, Richard D, Kennedy, Paul B, Mullan, Paula M, Gilmore, Michael, Carty, Patrick G, Johnston, D Paul, Harkin
Publikováno v:
Cancer research. 63(19)
We have evaluated the role played by BRCA1 in mediating the phenotypic response to a range of chemotherapeutic agents commonly used in cancer treatment. Here we provide evidence that BRCA1 functions as a differential mediator of chemotherapy-induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3e682ddc117ecc34c32c14f094f7a893
https://pubmed.ncbi.nlm.nih.gov/14559807
https://pubmed.ncbi.nlm.nih.gov/14559807
Publikováno v:
Human immunology. 65(6)
A polymerase chain reaction sequence-specific oligonucleotide probe typing method identifying and distinguishing alleles of the KIR2DS4 gene has been established. The system is based on the specific amplification of a region of this gene, followed by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7286b3ff20d9507d2b23ed89230cd18
https://pubmed.ncbi.nlm.nih.gov/15219381
https://pubmed.ncbi.nlm.nih.gov/15219381
Publikováno v:
Human Immunology. 64:S167
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f5da06da99254d49f4ed86065db44ee
https://doi.org/10.1016/j.humimm.2003.08.317
https://doi.org/10.1016/j.humimm.2003.08.317
Autor:
Cathy M McGeough, Rodat T. Cunningham, Clare Mathews, Paula M. Gilmore, Gary Wright, Daniel Berrar, Anthony J. Bjourson
Publikováno v:
Rheumatology International
The identification of patients who will respond to anti-tumor necrosis factor alpha (anti-TNF-α) therapy will improve the efficacy, safety, and economic impact of these agents. We investigated whether killer cell immunoglobulin-like receptor (KIR) g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::395bd220417828e125ddbcc3647886c1