Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Paula M. Gallagher"'
Autor:
Gregory J. Lowe, Noel G. McElvaney, Clifford C. Taggart, Catherine M. Greene, Shane J. O'Neill, Paula M. Gallagher
Publikováno v:
The Journal of Infectious Diseases. 188:769-776
Protease-antiprotease balance in 17 patients with unilateral community-acquired pneumonia (CAP) was characterized (day 6+/-0.8). Levels and activities of alpha-1 antitrypsin (A1AT), secretory leucoprotease inhibitor (SLPI), and neutrophil elastase (N
Autor:
Noel G. McElvaney, Shane J. O'Neill, Tomás P. Carroll, Clifford C. Taggart, Paula M. Gallagher, Catherine M. Greene, Deirdre E. Walsh
Publikováno v:
Journal of Biological Chemistry. 276:35494-35499
Cystic fibrosis is characterized in the lungs by neutrophil-dominated inflammation mediated significantly by neutrophil elastase (NE). Previous work has shown that NE induces interleukin-8 (IL-8) gene expression and protein secretion in bronchial epi
Autor:
Paula M. Gallagher, Kerry Schwichtenberg, Alexander S. Whitehead, Michael Y. Tsai, Pat Ward, E. R. Naughten, Sufin Yap, Naomi Q. Hanson, Michelle Bignell, Min Yuan
Publikováno v:
Molecular Genetics and Metabolism. 65:298-302
We used single-strand conformational polymorphism and nucleotide sequencing to characterize defective cystathionine beta-synthase gene alleles in 18 independent Irish patients with homocystinuria. Six mutations were detected, three of which have been
Autor:
Iwao Teraoka, Paula M. Gallagher-Wetmore, Arnost Reiser, Huifang Zhuang, Jonathan Goodman, Hsiao Yi Shih
Publikováno v:
Macromolecules. 31:1208-1213
An interpretation of the effect of resin molecular weight on the dissolution of Novolak is offered. It is based on Eyring's transition state theory and on the percolation model of Novolak dissolution. The rate-determining step of Novolak dissolution
Autor:
Helga Refsum, Alexander S. Whitehead, Cecilia E. Kim, Anne Berit Guttormsen, Paula M. Gallagher, Leiv Ose, Warren D. Kruger, Michael Y. Tsai, Ivar Følling, Per Magne Ueland
Publikováno v:
Human Molecular Genetics. 6:2213-2221
Cystathionine beta-synthase (CBS) deficiency is an autosomal recessive disorder which results in extremely elevated levels of total plasma homocysteine (tHcy) and high risk of thromboembolic events. About half of all patients diagnosed with CBS defic
Publikováno v:
Advanced Materials. 9:1039-1043
Autor:
Ian D. Graham, Raymond Meleady, Rima Rozen, Alun Evans, Denis C. Shields, Kok Soon Tan, Alexander S. Whitehead, Dorothy McMaster, Paula M. Gallagher
Publikováno v:
Circulation. 94:2154-2158
Background Plasma homocysteine levels are modulated by nutritional and genetic factors, among which is the enzyme methylenetetrahydrofolate reductase (MTHFR). A common defective (thermolabile) variant of this enzyme is causally associated with elevat
Autor:
Val J. Krukonis, Jeffrey T. Koberstein, Claire A. Jalbert, Iskender Yilgor, Paula M. Gallagher
Publikováno v:
Macromolecules. 26:3069-3074
The surface tensions of amine-, hydroxyl-, and methyl-terminated poly(dimethylsiloxane) (PDMS) oligomers with molecular weights ranging from 1000 to 75 000 are measured by pendant drop tensiometry. The surface tension increases with molecular weight
Publikováno v:
The Journal of Supercritical Fluids. 5:130-142
Recrystall ization of cyclotrimethylenetrinitramine (RDX) using gas anti-solvents was investigated. RDX, an extremely sensitive high explosive, is difficult to recrystallize by conventional procedures in a form free of intragranular cavities. For exa
Autor:
Gerard Meachery, Noel G. McElvaney, Shane J. O'Neill, Catherine M. Greene, Deirdre Kelly, Paula M. Gallagher, Clifford C. Taggart, Michael O'Mahony
Publikováno v:
American journal of respiratory and critical care medicine. 172(10)
Sarcoidosis is a granulomatous disease of unknown etiology characterized by a helper T-cell type 1-mediated process. Previously we demonstrated a role for interleukin-18 in sarcoidosis. Here we examine the regulation of interleukin-18 in this conditi