Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Paula M. Chilton"'
Autor:
Paula M. Chilton, Smita S. Ghare, Benjamin T. Charpentier, Scott A. Myers, Aakarsha V. Rao, Joseph F. Petrosino, Kristi L. Hoffman, John C. Greenwell, Neetu Tyagi, Jyotirmaya Behera, Yali Wang, Lucy J. Sloan, JingWen Zhang, Christopher B. Shields, Gregory E. Cooper, Leila Gobejishvili, Scott R. Whittemore, Craig J. McClain, Shirish S. Barve
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Alterations in the gut-microbiome-brain axis are increasingly being recognized to be involved in Alzheimer’s disease (AD) pathogenesis. However, the functional consequences of enteric dysbiosis linking gut microbiota and brain pathology in AD progr
Externí odkaz:
https://doaj.org/article/68fececdccb84cc983088b9ee897f11c
Autor:
Bodduluri Haribabu, Venkatakrishna R. Jala, Alberto Mantovani, Massimo Locati, Sergio Lira, Thomas C. Mitchell, Paula M. Chilton, Shuchismita R. Satpathy, Elangovan Krishnan, Paramahamsa Maturu, Steven Mathis, Sobha R. Bodduluri
The presence of mast cells in some human colorectal cancers is a positive prognostic factor, but the basis for this association is incompletely understood. Here, we found that mice with a heterozygous mutation in the adenomatous polyposis coli gene (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ba8185feaca01381d5ef228fbfe2ac1
https://doi.org/10.1158/2326-6066.c.6549286
https://doi.org/10.1158/2326-6066.c.6549286
Autor:
Bodduluri Haribabu, Venkatakrishna R. Jala, Alberto Mantovani, Massimo Locati, Sergio Lira, Thomas C. Mitchell, Paula M. Chilton, Shuchismita R. Satpathy, Elangovan Krishnan, Paramahamsa Maturu, Steven Mathis, Sobha R. Bodduluri
S1: Unaltered tumor burden in colons of ACKR2-/-ApcMin/+ mice. S2: Delayed onset of tumor development in the small intestine of ACKR2-/-ApcMin/+ mice. S3. Decreased inflammatory markers in the distal intestine tumors of ACKR2-/-ApcMin/+ mice. S4. Ele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f2f416398d1718a7887023d3ba3a209
https://doi.org/10.1158/2326-6066.22540117
https://doi.org/10.1158/2326-6066.22540117
Autor:
Efrain Farias-Cisneros, Paula M Chilton, Michelle D Palazzo, Tuna Ozyurekoglu, Jay B Hoying, Stuart K Williams, Carter Baughman, Christopher M Jones, Christina L Kaufman
Publikováno v:
SAGE Open Medicine, Vol 7 (2019)
Objectives: The goal of this study was to define the parameters of movement of indocyanine green in the upper extremity of normal control and hand transplant recipients. The purpose was to establish a non-invasive method of determining the level of l
Externí odkaz:
https://doaj.org/article/e462fa9ab3124770a0119c52cf81802a
Autor:
Rajesh K. Sharma, Venkatakrishna R. Jala, Sweta Ghosh, Michelle E Smith, Zinal Chheda, Rajbir Singh, Sobha R. Bodduluri, Jun Yan, Bodduluri Haribabu, Steven P. Mathis, Paula M. Chilton, Chris Fleming, Rob Knight
Publikováno v:
International Journal of Cancer. 148:2594-2607
The biological activities of chemokine (C-C motif) ligand 2 (CCL2) are mediated via C-C chemokine receptor-2 (CCR2). Increased CCL2 level is associated with metastasis of many cancers. In this study, we investigated the role of the CCL2/CCR2 axis in
Autor:
Swati Joshi-Barve, Paula M. Chilton, Paula Peyrani, Kendall J. Bryant, Andrea Reyes Vega, Mathew Freiberg, Robert L. Cook, Craig J. McClain, Aakarsha V Rao, Smita Ghare, Shirish Barve
Publikováno v:
J Acquir Immune Defic Syndr
BACKGROUND: Chronic immune activation and CD4(+) T cell depletion are significant pathogenic features of HIV infection. Expression of Fas ligand (FasL), a key mediator of activation-induced cell death in T cells, is elevated in people living with HIV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f4da2c186eed7a98a3a59415d935cee
https://europepmc.org/articles/PMC8384352/
https://europepmc.org/articles/PMC8384352/
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56855 (2013)
Toll like receptor 4 (TLR4) is an important pattern recognition receptor with the ability to drive potent innate immune responses and also to modulate adaptive immune responses needed for long term protection. Activation of TLR4 by its ligands is med
Externí odkaz:
https://doaj.org/article/b55007ab3cd348daa46501a66805f4ab
Autor:
Katlin B. Stivers, Jason E. Beare, Amanda J. LeBlanc, Pascale Alard, Paula M. Chilton, Jacob R. Dale, James B. Hoying
Publikováno v:
Immunology and cell biologyReferences. 98(8)
The metabolically dynamic nature of healthy adipose places this tissue under regular inflammatory stress. A network of adipose-resident anti-inflammatory immune cells modulates and resolves this endogenous inflammation. Previous work in our laborator
Publikováno v:
Frontiers in Immunology, Vol 3 (2012)
The vertebrate immune system exists in equilibrium with the microbial world. The innate immune system recognizes pathogen-associated molecular patterns via a family of Toll-like receptors that activate cells upon detection of potential pathogens. Bec
Externí odkaz:
https://doaj.org/article/a6720bd92499469f9c7af73f52e6b010
Autor:
Mary Proctor, Sarah A. Wilcher, Jino Park, Shin-je Ghim, Joongho Joh, A. B. Jenson, Maryam Zahin, Paula M. Chilton
Publikováno v:
Experimental and Molecular Pathology. 103:181-190
Previous studies of naturally occurring mouse papillomavirus (PV) MmuPV1-induced tumors in B6.Cg-Foxn1nu/nu mice suggest that T cell deficiency is necessary and sufficient for the development of such tumors. To confirm this, MmuPV1-induced tumors wer