Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Paula M Canas"'
Autor:
Daniel eRial, Cristina eLemos, Helena ePinheiro, Joana M Duarte, Francisco Q Gonçalves, Joana Isabel Real, Rui Daniel Prediger, Nélio eGonçalves, Catarina A. Gomes, Paula M Canas, Paula eAgostinho, Rodrigo A Cunha
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 9 (2016)
Recent studies combining pharmacological, behavioral, electrophysiological and molecular approaches indicate that depression results from maladaptive neuroplastic processing occurring in defined frontolimbic circuits responsible for emotional process
Externí odkaz:
https://doaj.org/article/15e34705fce34fb1bbde9075e38970a7
Autor:
Joana E Coelho, Pedro eAlves, Paula M Canas, Jorge S Valadas, Vania L Batalha, Diana G Ferreira, Tatiana eShmidt, Joaquim Alexandre Ribeiro, Michael eBader, Rodrigo A Cunha, Frederico eSimões do Couto, Luisa V Lopes
Publikováno v:
Frontiers in Psychiatry, Vol 5 (2014)
Adenosine A2A receptors (A2AR) are a sub-type of receptors enriched in basal ganglia, activated by the neuromodulator adenosine, which interact with dopamine D2 receptors. Although this reciprocal antagonistic interaction is well established in motor
Externí odkaz:
https://doaj.org/article/6c5182f2b39245c2af7661390804b0d5
Autor:
Hai-Ying Shen, Paula M Canas, Patricia Garcia-Sanz, Jing-Quan Lan, Detlev Boison, Rosario Moratalla, Rodrigo A Cunha, Jiang-Fan Chen
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80902 (2013)
Adenosine A2A receptors (A2AR) are located postsynaptically in striatopallidal GABAergic neurons, antagonizing dopamine D2 receptor functions, and are also located presynaptically at corticostriatal terminals, facilitating glutamate release. To addre
Externí odkaz:
https://doaj.org/article/7f71e037f8274c1082d7da34a1bce050
Autor:
Ana P. Simões, Marina A. M. Portes, Cátia R. Lopes, Felipe Vanz, Vanessa S. Lourenço, Anna Pliássova, Ingride L. Gaspar, Henrique B. Silva, Ângelo R. Tomé, Paula M. Canas, Rui D. Prediger, Rodrigo A. Cunha
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Fear learning is essential to survival, but traumatic events may lead to abnormal fear consolidation and overgeneralization, triggering fear responses in safe environments, as occurs in post-traumatic stress disorder (PTSD). Adenosine A2A re
Externí odkaz:
https://doaj.org/article/3834a2837f16481986b09c5d0cbaafe9
Autor:
Cátia R. Lopes, António C. Silva, Henrique B. Silva, Paula M. Canas, Paula Agostinho, Rodrigo A. Cunha, João Pedro Lopes
Publikováno v:
Biomolecules, Vol 13, Iss 8, p 1173 (2023)
The intracerebroventricular (icv) injection of amyloid peptides (Aβ) models Alzheimer’s disease (AD) in mice, as typified by the onset within 15 days of deficits of memory and of hippocampal long-term potentiation (LTP) that are prevented by the b
Externí odkaz:
https://doaj.org/article/9889209a01ac4ec1a0d7451a1a94d22a
Autor:
Cátia R. Lopes, Andreia Oliveira, Ingride Gaspar, Matilde S. Rodrigues, Joana Santos, Eszter Szabó, Henrique B. Silva, Ângelo R. Tomé, Paula M. Canas, Paula Agostinho, Rui A. Carvalho, Rodrigo A. Cunha, Ana Patrícia Simões, João Pedro Lopes, Samira G. Ferreira
Publikováno v:
Biomolecules, Vol 13, Iss 1, p 106 (2023)
Adenosine receptors mainly control synaptic function, and excessive activation of adenosine receptors may worsen the onset of many neurological disorders. Accordingly, the regular intake of moderate doses of caffeine antagonizes adenosine receptors a
Externí odkaz:
https://doaj.org/article/c1dfbb01209e4e63a8978f837859d8ba
Adenosine A2A receptors blockade attenuates dexamethasone-induced alterations in cultured astrocytes
Autor:
Daniela Madeira, Liliana Dias, Patrícia Santos, Rodrigo A. Cunha, Paula Agostinho, Paula M. Canas
Publikováno v:
Purinergic Signalling. 18:199-204
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f75851b2c681ad2e085f9ef0cfe89f88
https://doi.org/10.1007/s11302-022-09864-4
https://doi.org/10.1007/s11302-022-09864-4
Autor:
Patrícia Santos, Daniela Madeira, Paula Agostinho, Paula M. Canas, Rodrigo A. Cunha, Liliana Dias
Publikováno v:
Molecular Neurobiology. 58:6232-6248
Increasing evidence implicates astrocytes and the associated purinergic modulation in Alzheimer's disease (AD), characterized by cognitive deficits involving the extracellular amyloid-β peptides (Aβ) accumulation. Aβ can affect astrocytic gliotran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ef51b7d53e0345ae46c203e88248544
https://doi.org/10.1007/s12035-021-02538-z
https://doi.org/10.1007/s12035-021-02538-z
Autor:
Brígida R. Pinho, Ana I. Duarte, Paula M. Canas, Paula I. Moreira, Michael P. Murphy, Jorge M.A. Oliveira
Publikováno v:
Free Radical Biology and Medicine. 198:S5-S6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9623cf360b1c990e2c69a4be810f7e2
https://doi.org/10.1016/j.freeradbiomed.2022.12.030
https://doi.org/10.1016/j.freeradbiomed.2022.12.030