Zobrazeno 1 - 10
of 151
pro vyhledávání: '"Paula M, O'Connor"'
Autor:
Rocio Sanchez-Gallardo, Paula M. O’Connor, Ian J. O’Neill, Brian McDonnell, Ciaran Lee, Rebecca L. Moore, Fionnuala M. McAuliffe, Paul D. Cotter, Douwe van Sinderen
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Bacteriocins are broad or narrow-spectrum antimicrobial compounds that have received significant scientific attention due to their potential to treat infections caused by antibiotic-resistant pathogenic bacteria. The genome of Bifidobacterium pseudoc
Externí odkaz:
https://doaj.org/article/ae577354e2314282907f25466435ad2f
Autor:
Michelle O’Connor, Paula M. O’Connor, David Hourigan, Ellen Murray, Felipe Miceli de Farias, Des Field, Colin Hill, R. Paul Ross
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
IntroductionAntimicrobial-resistant pathogens present an ongoing threat to human and animal health, with deaths linked to antimicrobial resistance (AMR) predicted to increase annually. While the misuse and overuse of antibiotics in humans undoubtedly
Externí odkaz:
https://doaj.org/article/24a0b5ad9f684ecc9cbe3b52ae88ef5a
Autor:
Natalia S. Ríos Colombo, Mariana Perez-Ibarreche, Lorraine A. Draper, Paula M. O’Connor, Des Field, R. Paul Ross, Colin Hill
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Bacteriocins are antimicrobial peptides that have been studied for decades as food bio-preservatives or as alternatives to antibiotics. They also have potential as modulators of the gut microbiome, which has been linked to human health. However, it i
Externí odkaz:
https://doaj.org/article/7c8c3dc84b904866928d13a184eac822
Autor:
Catherine O’Reilly, Ghjuvan M. Grimaud, Mairéad Coakley, Paula M. O’Connor, Harsh Mathur, Veronica L. Peterson, Ciara M. O’Donovan, Peadar G. Lawlor, Paul D. Cotter, Catherine Stanton, Mary C. Rea, Colin Hill, R. Paul Ross
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Nisin is a broad spectrum bacteriocin used extensively as a food preservative that was identified in Lactococcus lactis nearly a century ago. We show that orally-ingested nisin survives transit through the porcine gastrointestinal tract inta
Externí odkaz:
https://doaj.org/article/c093ba8175f84cbda8fecad55b6d5579
Autor:
Ellen Twomey, Paula M. O’Connor, Aidan Coffey, Maija Kiste, Caitriona M. Guinane, Colin Hill, Des Field, Máire Begley
Publikováno v:
Antibiotics, Vol 13, Iss 4, p 338 (2024)
Staphylococcus aureus is frequently highlighted as a priority for novel drug research due to its pathogenicity and ability to develop antibiotic resistance. Coagulase-negative staphylococci (CoNS) are resident flora of the skin and nares. Previous st
Externí odkaz:
https://doaj.org/article/1dfc46258aa1412a8bed95e4eec6fbe6
Autor:
Garreth W. Lawrence, Niamh McCarthy, Calum J. Walsh, Tais M. Kunyoshi, Elaine M. Lawton, Paula M. O’Connor, Máire Begley, Paul D. Cotter, Caitriona M. Guinane
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
The gut microbiome is a vast reservoir of microbes, some of which produce antimicrobial peptides called bacteriocins that may inhibit specific bacteria associated with disease. Fusobacterium nucleatum is an emerging human bacterial pathogen associate
Externí odkaz:
https://doaj.org/article/7038674fa77840058b18465755ebd624
Autor:
Taís M. Kuniyoshi, Paula M. O’Connor, Elaine Lawton, Dinesh Thapa, Beatriz Mesa-Pereira, Sara Abulu, Colin Hill, R. Paul Ross, Ricardo P. S. Oliveira, Paul D. Cotter
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
Pediocin PA-1 is a class IIa bacteriocin that is particularly effective against the foodborne pathogen Listeria monocytogenes. The loss of activity of PA-1 pediocin due to methionine oxidation is one of the challenges that limit the wider application
Externí odkaz:
https://doaj.org/article/e4fe0f09b56f466598e24ccecf64a5a7
Autor:
Daragh Hill, Paula M. O’Connor, Eric Altermann, Li Day, Colin Hill, Catherine Stanton, R. Paul Ross
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Abstract Streptococcus gallolyticus LL009 produces gallocin D, a narrow spectrum two component bacteriocin with potent activity against vancomycin-resistant enterococci. Gallocin D is distinct from gallocin A, a separate two component bacteriocin pro
Externí odkaz:
https://doaj.org/article/5a7ab2021620431b8b09b3f9a2ed97e4
Autor:
Ivan Sugrue, Daragh Hill, Paula M. O’Connor, Li Day, Catherine Stanton, Colin Hill, R. Paul Ross
Publikováno v:
Microorganisms, Vol 11, Iss 2, p 427 (2023)
Nisin A, the prototypical lantibiotic, is an antimicrobial peptide currently utilised as a food preservative, with potential for therapeutic applications. Here, we describe nisin E, a novel nisin variant produced by two Streptococcus equinus strains,
Externí odkaz:
https://doaj.org/article/13ccd1bca2cd473485b2c27d5de70000
Autor:
Patthanasak Rungsirivanich, Elvina Parlindungan, Paula M. O’Connor, Des Field, Jennifer Mahony, Narumol Thongwai, Douwe van Sinderen
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Bacillus velezensis ML122-2 is an antimicrobial-producing strain isolated from the leaf of Assam tea or Miang [Camellia sinensis var. assamica (J.W.Mast.) Kitam.]. The cell-free supernatant (CFS) of strain ML122-2 exhibits a broad-spectrum antimicrob
Externí odkaz:
https://doaj.org/article/fa87c892e8f642a5988fcbe15dbd3bdb